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Cited by 130Asthma and respiratory diseasesChronic Obstructive Pulmonary Disease (COPD) ResearchOccupational exposure and asthma

The DOI matches its Crossref record; 64 of the 65 references it cites were found in a registry or an index.

Impact of depressive symptoms on adult asthma outcomes

Eisner, Mark D., Katz, Patricia P., Lactao, Gretchen, Iribarren, Carlos·2005·Annals of Allergy, Asthma & Immunology
DOI 10.1016/s1081-1206(10)61135-0
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Abstract

Background Psychological disorders, including depression, are common in adults with asthma. Although depression is treatable, its impact on longitudinal asthma outcomes is not clear.Objective To elucidate the impact of depressive symptoms on patient-centered outcomes and emergency health care use in adults with asthma.Methods We conducted a prospective cohort study of 743 adults with asthma who were recruited after hospitalization for asthma. Depressive symptoms were defined as having a score of 16 or more on the Center for Epidemiologic Studies Depression Scale. We examined the impact of depressive symptoms on patient-centered outcomes (validated severity-of-asthma score, Marks Asthma Quality of Life Questionnaire, and 12-Item Short-Form Health Survey physical component summary score) and on future emergency health care use for asthma ascertained from computerized databases.Results The prevalence of depressive symptoms was 18% (95% confidence interval [CI], 15%-21%) among adults with asthma. Depressive symptoms were associated with greater severity-of-asthma scores after controlling for age, sex, race/ ethnicity, educational attainment, and cigarette smoking (mean score increment, 2.6 points; 95% CI, 1.8-3.4 points). Furthermore, depressive symptoms were associated with poorer asthma-specific quality of life (mean score increment, 19.9 points; 95% CI, 17.7-22.1 points) and poorer physical health status (mean score decrement, 3.7 points; 95% CI, 1.5-5.8 points). Depressive symptoms were associated with a greater longitudinal risk of hospitalization for asthma (hazard ratio, 1.34; 95% CI, 0.98-1.84). After controlling for differences in preventive care for asthma, the relationship was stronger (hazard ratio, 1.45; 95% CI, 1.05-2.0).Conclusion Depressive symptoms are common in adults with asthma and are associated with poorer health outcomes, including greater asthma severity and risk of hospitalization for asthma.

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Crossref · 10.1016/s1081-1206(10)61135-0

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Research works printed but not linked: 3

  1. Mannino, 1998, Surveillance for asthma-United States, 1960–1995, MMWR Morb Mortal Wkly Rep, 47, 1
  2. Eisner, 2002, Intensive care unit admission for asthma: a marker of severe disease [abstract], Am J Respir Crit Care Med, 165, A121
  3. Cigarette smoking among adults-United States, 1997, 1999, MMWR Morb Mortal Wkly Rep, 48, 993

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Metadata

Authors
Eisner, M. D., Katz, P. P., Lactao, G., & Iribarren, C.
Affiliations
  • University of California, San Francisco (US)
  • Kaiser Permanente (US)
Corresponding author
Eisner, Mark D.
ORCID
Venue
Annals of Allergy, Asthma & Immunology
Publisher
Elsevier BV
Published
2005-05
Volume
94
Issue
5
Pages
566-574
ISSN
1081-1206 (ISSN-L)
DOI
10.1016/s1081-1206(10)61135-0
OpenAlex
W2039110930
Cited by
130
References
65
Citations by year
2025: 3 · 2024: 3 · 2023: 2 · 2022: 7 · 2021: 2 · 2020: 4 · 2019: 5 · 2018: 9 · 2017: 6 · 2016: 7 · 2015: 6 · 2014: 3 · 2013: 6 · 2012: 13
FWCI
5.42
Type
journal article
Language
en
Open access
closed
Licence
Locations
  • Annals of Allergy Asthma & Immunology (publishedVersion)
  • PubMed (publishedVersion)
Funders
National Heart, Lung, and Blood Institute (K23HL004201, K23 HL-04201)
Topics
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Asthma and respiratory diseases
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Occupational exposure and asthma
Keywords
depressive symptoms, depression, asthma, asthma severity, asthma-specific quality of life, physical health status, emergency department visits, asthma hospitalization, patient-centered outcomes, psychological comorbidity
MeSH terms
Adult, Asthma, California, Depression, Female, Health Status, Hospitalization, Humans, Male, Prospective Studies, Quality of Life, Surveys and Questionnaires, Risk Factors, Cohort Studies, Prevalence

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