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DRUG-INDUCED LIVER DISEASE

Zimmerman, Hyman J.·2000·Clinics in Liver Disease
DOI 10.1016/s1089-3261(05)70097-0
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Abstract

Drug-induced liver disease may account for between 10% and 50% of adult patients with elevated enzymes, especially in patients over age 50 years. It accounts for nearly 25% of patients with fulminant hepatic failure. Liver injury can be cytotoxic, cholestatic, or mixed. A variety of systemic manifestations can accompany drug-induced hepatotoxicity. Drug-induced liver disease can mimic autoimmune hepatitis or it can evolve to cirrhosis. It can also mimic veno-occulusive disorders. The plethora of herbal and traditional agents currently ingested by many people should always be considered in any patient with abnormal hepatic biochemistry.

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Research works printed but not linked: 43

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Metadata

Authors
Zimmerman, H. J.
Venue
Clinics in Liver Disease
Publisher
Elsevier BV
Published
2000-02
Volume
4
Issue
1
Pages
73-96
ISSN
1089-3261
DOI
10.1016/s1089-3261(05)70097-0
Cited by
186
References
0
Language
en
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)

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