Understanding the multiple functions of Nramp1

Cloning and characterization of a mammalian proton-coupled metal-ion transporter

Gunshin, H., Mackenzie, B., Berger, U. V., Gunshin, Y., Romero, M. F., Boron, W. F., Nussberger, S., Gollan, J. L., & Hediger, M. A. (1997) · Nature · doi:10.1038/41343 · Cited by 3,166

Lack of Acidification in Mycobacterium Phagosomes Produced by Exclusion of the Vesicular Proton-ATPase

Sturgill-Koszycki, S., Schlesinger, P. H., Chakraborty, P., Haddix, P. L., Collins, H. L., Fok, A. K., Allen, R. D., Gluck, S. L., Heuser, J., & Russell, D. G. (1994) · Science · doi:10.1126/science.8303277 · Cited by 1,302

Microcytic anaemia mice have a mutation in Nramp2, a candidate iron transporter gene

Fleming, M. D., Trenor, C. C., Su, M. A., Foernzler, D., Beier, D. R., Dietrich, W. F., & Andrews, N. C. (1997) · Nature Genetics · doi:10.1038/ng0897-383 · Cited by 1,159

Natural resistance to infection with intracellular parasites: isolation of a candidate for Bcg

Vidal, S. M., Malo, D., Vogan, K., Skamene, E., & Gros, P. (1993) · Cell · doi:10.1016/0092-8674(93)90135-d · Cited by 1,104

Nramp 2 is mutated in the anemic Belgrade ( b ) rat: Evidence of a role for Nramp2 in endosomal iron transport

Fleming, M. D., Romano, M. A., Su, M. A., Garrick, L. M., Garrick, M. D., & Andrews, N. C. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.3.1148 · Cited by 936

Variations in the NRAMP1 Gene and Susceptibility to Tuberculosis in West Africans

Bellamy, R., Ruwende, C., Corrah, T., McAdam, K. P. W. J., Whittle, H. C., & Hill, A. V. S. (1998) · New England Journal of Medicine · doi:10.1056/nejm199803053381002 · Cited by 738

The Ity/Lsh/Bcg locus: natural resistance to infection with intracellular parasites is abrogated by disruption of the Nramp1 gene

Vidal, S., Tremblay, M. L., Govoni, G., Gauthier, S., Sebastiani, G., Malo, D., Skamene, E., Olivier, M., Jothy, S., & Gros, P. (1995) · The Journal of experimental medicine · doi:10.1084/jem.182.3.655 · Cited by 603

Natural Resistance to Infection with Intracellular Pathogens: The Nramp1 Protein Is Recruited to the Membrane of the Phagosome

Gruenheid, S., Pinner, E., Desjardins, M., & Gros, P. (1997) · The Journal of Experimental Medicine · doi:10.1084/jem.185.4.717 · Cited by 428

Nramp2 is mutated in the anemic Belgrade (b) rat : evidence of a role for Nramp2 in endosomal iron transport

Flemming (1998) · Medical Entomology and Zoology · Cited by 412

Mycobacterium‐containing phagosomes are accessible to early endosomes and reflect a transitional state in normal phagosome biogenesis.

Sturgill‐Koszycki, S., Schaible, U. E., & Russell, D. G. (1996) · The EMBO Journal · doi:10.1002/j.1460-2075.1996.tb01088.x · Cited by 356

Burkholderia pseudomallei Evades Nramp1 (Slc11a1)- and NADPH Oxidase-Mediated Killing in Macrophages and Exhibits Nramp1-Dependent Virulence Gene Expression

Muangsombut, V., Withatanung, P., Srinon, V., Chantratita, N., Stevens, M. P., Blackwell, J. M., & Korbsrisate, S. (2017) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2017.00350 · Cited by 9

The functional SLC11A1 gene polymorphisms are associated with sarcoidosis in Turkish population

Akçakaya, P., Azeroglu, B., Even, I., Ateş, Ö., Türker, H., Öngen, G., & Topal-Sarikaya, A. (2011) · Molecular Biology Reports · doi:10.1007/s11033-011-1297-x · Cited by 9

Characterization of the NRAMP1 (SLC11A1) gene in the horse (Equus caballus L.)

Matiašovic, J., Kubı́čková, S., Musilová, P., Rubeš, J., & Hořín, P. (2002) · European Journal of Immunogenetics · doi:10.1046/j.1365-2370.2002.00348.x · Cited by 8

Efficient cadmium uptake and accumulation in pokeweed (Phytolacca americana L.) associated with its potential for phytoremediation of cadmium-polluted soils

Xia, Y., Yang, F., Hu, L., Ji, H., & Shao, J. F. (2025) · Plant and Soil · doi:10.1007/s11104-025-07401-x · Cited by 8

SLC11A1 Polymorphisms Are Associated with the Risk of Chronic Obstructive Pulmonary Disease in a Korean Population

Kim, E. J., Kim, K. M., Park, S. H., Kim, J. S., Lee, W. K., Ick, S., Kim, C. H., Kang, Y. M., Han, S. B., Jung, T. H., et al. (2008) · Biochemical Genetics · doi:10.1007/s10528-008-9166-6 · Cited by 8

Positive selection in the SLC11A1 gene in the family Equidae

Bayerová, Z., Jánová, E., Matiašovic, J., Orlando, L., & Hořín, P. (2016) · Immunogenetics · doi:10.1007/s00251-016-0905-2 · Cited by 7

Manganese and Nutritional Immunity

Juttukonda, L. J., & Skaar, E. P. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-802168-2.00031-2 · Cited by 9

Epigenetic regulation of SLC11a1 gene in horses infected with cyathostomins

Pires, V. D. S., Ganzella, F. A. D. O., Minozzo, G. A., de Castro, L. L. D., Moncada, A. D. B., Klassen, G., Ramos, E. A. D. S., & Molento, M. B. (2021) · Gene Reports · doi:10.1016/j.genrep.2021.101410 · Cited by 7

Altered expression of the iron transporter Nramp1 (Slc11a1) during fetal development of the retinal pigment epithelium in microphthalmia-associated transcription factor Mitfmi and Mitfvitiligo mouse mutants

Waes, J. G., Smith, L., Waes, M. V., Wilberding, J., Eudy, J. D., Bauer, L. K., & Maddox, J. R. (2007) · Experimental Eye Research · doi:10.1016/j.exer.2007.11.015 · Cited by 7

Genetic Variations Analysis and Characterization of the Fifth Intron of Porcine NRAMP1 Gene

Yan, X.-H., Ren, J. T., Ai, H., Ding, N., Gao, J., Guo, Y., Chen, C. Y., Ma, J. W., Shu, Q., & Huang, L. (2004) · Asian-Australasian Journal of Animal Sciences · doi:10.5713/ajas.2004.1183 · Cited by 7

Divalent metal transporter-related protein restricts animals to marine habitats

Sassa, M., Takagi, T., Kinjo, A., Yoshioka, Y., Zayasu, Y., Shinzato, C., Kanda, S., Murakami‐Sugihara, N., Shirai, K., & Inoue, K. (2021) · Communications Biology · doi:10.1038/s42003-021-01984-8 · Cited by 5

Comparison of Natural Resistance-Associated Macrophage Protein (NRAMP)1 Expression between Cows with High and Low Milk Somatic Cells Counts

Joo, Y. S., Moon, J.-S., Fox, L. K., Suh, G., Kwon, N.-H., Kim, S. H., & Park, Y. H. (2003) · Asian-Australasian Journal of Animal Sciences · doi:10.5713/ajas.2003.1830 · Cited by 6

Slc11a1 (formerly Nramp1) polymorphisms and susceptibility to post‐transplant lymphoproliferative disease following pediatric liver transplantation

Barshes, N. R., Lee, T. R., Goss, J. A., Goodpastor, S. E., Huls, M. H., Rooney, C. M., Karpen, S. J., & Wyllie, S. (2006) · Transplant Infectious Disease · doi:10.1111/j.1399-3062.2006.00139.x · Cited by 6

Role of Iron Metabolism in Multiple Sclerosis

Kotze, M. J., de Villiers, J. N. P., Zaahl, M. G., & Robson, K. (2003) · WORLD SCIENTIFIC eBooks · doi:10.1142/9789812796691_0016 · Cited by 6

Analysis of SLC11A1 gene expression in healthy water buffalo (Bubalus bubalis) blood cells using qPCR

Crisà, A., MATTEIS, G. D., Scatà, M. C., & Moioli, B. (2013) · Genetics and Molecular Research · doi:10.4238/2013.december.19.15 · Cited by 5

Association between rheumatoid arthritis and genetic variants of natural resistance‐associated macrophage protein 1 gene: A meta‐analysis

Wang, H., Yuan, F., Dai, Z., Wang, B., & Dong-qing, Y. (2018) · International Journal of Rheumatic Diseases · doi:10.1111/1756-185x.13366 · Cited by 5

Iron

Weiß, G. (2004) · Humana Press eBooks · doi:10.1007/978-1-59259-652-2_11 · Cited by 4

Natural resistance-associated macrophage protein-1 gene polymorphisms and genetic susceptibility to pulmonary tuberculosis in sudanese patients

Hamdan, H. Z., Yousif, Y. O. E., & Dosogi, W. A. A. (2021) · Bulletin of the Academy of Sciences of Moldova Medical Sciences · doi:10.52692/1857-0011.2021.1-69.14 · Cited by 3

Molecular characterization of the NRAMP1 gene in buffalo

MATTEIS, G. D., Napolitano, F., Scatà, M. C., Crisà, A., Catillo, G., Signorelli, F., Pacelli, C., & Moioli, M. (2009) · Italian Journal of Animal Science · doi:10.4081/ijas.2009.s2.72 · Cited by 3

Polimorfismos do gene NRAMP1 em indivíduos com reações hansênicas, atendidos em dois Centros de Referência no Recife, nordeste do Brasil NRAMP1 gene polymorphisms in individuals with leprosy reactions attended at two reference centers in Recife, northeastern Brazil

de Almeida, M. R., Teixeira, G., Silva, N. L., Ramos, A. D. L., Hatagima, A., & Magalhães, V. (2010) · Cited by 3

Genotipificación de la región 3´UTR del gen Nramp1, en ganado Holstein y en criollo Hartón del Valle

Bravo, E. T., & Llanos, Y. V. (2016) · Revista Colombiana de Ciencias Pecuarias · doi:10.17533/udea.rccp.324097 · Cited by 2

Molecular regulation of iron homeostasis and resistance to infection in alcoholics

Potter, B. J. (2002) · Frontiers in bioscience · doi:10.2741/a848 · Cited by 2

Linkage of Pteridine Metabolism to Iron Homeostasis

Weiß, G. (2004) · Pteridines · doi:10.1515/pteridines.2004.15.3.120 · Cited by 1

T178 deletion impairs intermolecular interaction of the peptide Nramp1(164–191)

Xue, R., Wang, S., Qi, H., Song, Y., Xiao, S., & Li, F. (2009) · Journal of Peptide Science · doi:10.1002/psc.1128 · Cited by 1

NRAMP1 Gene Polymorphism and Susceptibility to Cutaneous Leishmaniasis in Iraq

Alomashi, G. B. A., & Khudhur, H. R. (2017) · Nano Biomedicine and Engineering · doi:10.5101/nbe.v9i4.p333-336 · Cited by 1

Molecular Cloning and Functional Characterization of the 5′ Regulatory Region of the SLC11A1 Gene from Yaks

Chong, Y., Wang, L., Wang, B., Gao, Z., Lu, Y., Deng, W., & Xi, D. (2023) · Animals · doi:10.3390/ani13233615 · Cited by 1

An Exhaustive Structural Scrutiny and Initial Functional Appraisal of the Yak SLC11A1 Gene

Wang, L., Wang, B., Gao, Z., LU, Y., Deng, W., Xi, D., & Chong, Y. (2024) · Russian Journal of Genetics · doi:10.1134/s102279542404015x · Cited by 1

Investigations of genetic polymorphisms related to Behcet\s disease in Turkish population

Oğuz, E., Demiryürek, A. T., Alaşehirli, B., & Onat, A. M. (2013) · Gaziantep medical journal · doi:10.5455/gmj-30-47080 · Cited by 1

Effect of NRAMP1 Gene Polymorphism on levels off (TNF- and #945;1and IL-1beta) cytokines in Cutaneous Leishmaniasis patients in Iraq

Khudhur, H. R., & Alomashi, G. B. A. (2018) · Journal of Immunology and Clinical Microbiology · doi:10.5455/jicm.30.20180422 · Cited by 1

Molecular regulation of iron homeostasis and resistance to infection in alcoholics

Barry, J. P. (2002) · Frontiers in bioscience · doi:10.2741/potter · Cited by 1

Mycobacterium tuberculosis-specific T-cell responses in latent infection and active disease

Schuck, S. D. (2009) · edoc Publication server (Humboldt University of Berlin) · doi:10.18452/15916

Variation of Interleukin-8 (IL-8) Receptor Gene Based on Single Strand Conformation Polymorphism (SSCP) in Indonesian Friesian Holstein Dairy Cattle

Winaya, A., & Rahayu, I. (2010) · UMM Institutional Repository (University of Maine at Machias)

Identification and Association of Bovine CXCR2 Single Nucleotide Polymorphisms with Clinical and Subclinical Mastitis in Holstein and Jersey Cattle

Youngerman, S. M. (2004)

Participação do gene Slc11a1 na modulação da resposta imune na artrite induzida por pristane em camundongos selecionados para resposta inflamatória aguda.

Corrêa, M. A. (2015) · doi:10.11606/t.42.2015.tde-10062015-093513

Development of in vitro models to study the rapid extraintestinal dissemination of salmonella.

Gopinath, A. (2020) · ThinkIR: The University of Louisville's Institutional Repository (University of Louisville) · doi:10.18297/etd/3381

DNA Delivery with Attenuated Intracellular Bacteria

Fensterle, J., & Kaufmann, S. H. E. (2003) · Springer eBooks · doi:10.1007/978-1-4615-0105-3_15

Nramp1 phagocyte intracellular metal withdrawal defense

Cellier, M. F., Courville, P., & Campion, C. (2007) · Microbes and Infection · doi:10.1016/j.micinf.2007.09.006 · Cited by 203

Nramp1

Gruenheid, S., Skamene, E., & Gros, P. (1999) · Advances in cellular and molecular biology of membranes and organelles · doi:10.1016/s1874-5172(99)80039-x · Cited by 3

Divalent-metal transport by NRAMP proteins at the interface of host–pathogen interactions

Forbes, J. R., & Gros, P. (2001) · Trends in Microbiology · doi:10.1016/s0966-842x(01)02098-4 · Cited by 424

Induction of Nramp2 in activated mouse macrophages is dissociated from regulation of the Nramp1, classical inflammatory genes, and genes involved in iron metabolism

Wardrop, S. L., Wells, C. A., Ravasi, T., Hume, D. A., & Richardson, D. R. (2002) · Journal of Leukocyte Biology · doi:10.1189/jlb.71.1.99 · Cited by 19

SLC11 family of H + -coupled metal-ion transporters NRAMP1 and DMT1

Mackenzie, B., & Hediger, M. A. (2004) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-003-1141-9 · Cited by 127