The DOI matches its Crossref record; 83 of the 86 references it cites were found in a registry or an index.
Target cells in vaginal HIV transmission
Open accessAbstract
Understanding the mechanisms of HIV transmission to women will be crucial to the development of effective strategies to curb this epidemic. Current data suggest that HIV has at least two routes to penetrate the vaginal epithelium and reach lymphoid tissues, trans-epithelial migration of infected Langerhans cells or virus penetration into the lamina propria through loss of epithelial integrity resulting in direct infection of lymphocytes, dendritic cells and macrophages.
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“APCs, such as DCs and macrophages, are the first targets of HIV-1 and HTLV-1 during transmission via sexual routes and breastfeeding [56,57,58,59].”
From HIV-1 and HTLV-1 Transmission Modes: Mechanisms and Importance for Virus Spread (2022) · cites this paper as [56]
Citations
Cites
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CC CKR5: A RANTES, MIP-1α, MIP-1β Receptor as a Fusion Cofactor for Macrophage-Tropic HIV-1
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Research works printed but not linked: 1
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Cited by
Sorted by citations
The role of sexually transmitted diseases in HIV transmission
Galvin, S., & Cohen, M. S. (2004) · Nature Reviews Microbiology · doi:10.1038/nrmicro794 · Cited by 782
Targeting early infection to prevent HIV-1 mucosal transmission
Haase, A. T. (2010) · Nature · doi:10.1038/nature08757 · Cited by 591
Semen-Derived Amyloid Fibrils Drastically Enhance HIV Infection
Münch, J., Rücker, E., Ständker, L., Adermann, K., Goffinet, C., Schindler, M., Wildum, S., Chinnadurai, R., Rajan, D., Specht, A., et al. (2007) · Cell · doi:10.1016/j.cell.2007.10.014 · Cited by 544
Inhibiting sexual transmission of HIV-1 infection
Shattock, R. J., & Moore, J. P. (2003) · Nature Reviews Microbiology · doi:10.1038/nrmicro729 · Cited by 506
Self-citationMoore, J. P., Kitchen, S. G., Pugach, P., & Zack, J. A. (2004) · AIDS Research and Human Retroviruses · doi:10.1089/088922204322749567 · Cited by 492
Metadata
- Authors
- Miller, C. J., & Shattock, R. J.
- Affiliations
- University of California, Davis (US)
- St George's, University of London (GB)
- Corresponding author
- Miller, Christopher J.
- Venue
- Microbes and Infection
- Publisher
- Elsevier BV
- Published
- 2003-01
- Volume
- 5
- Issue
- 1
- Pages
- 59-67
- ISSN
- 1286-4579 (ISSN-L)
- OpenAlex
- W2028603136
- Cited by
- 220
- References
- 86
- Citations by year
- 2024: 1 · 2023: 2 · 2022: 1 · 2021: 6 · 2020: 2 · 2019: 6 · 2018: 8 · 2017: 4 · 2016: 7 · 2015: 10 · 2014: 22 · 2013: 9 · 2012: 13
- FWCI
- 2.22
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Microbes and Infection (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Rockefeller Foundation
- Topics
- Life Sciences › Immunology and Microbiology › Virology › HIV Research and Treatment
- Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
- Life Sciences › Immunology and Microbiology › Microbiology › Reproductive tract infections research
- Keywords
- HIV transmission, target cells, vaginal epithelium, Langerhans cells, lamina propria, lymphoid tissue, dendritic cells, macrophages, epithelial barrier integrity, women
- MeSH terms
- Animals, Epithelium, Female, HIV, Humans, Immunologic Factors, Macaca, Vagina, Simian Immunodeficiency Virus, HIV Infections, Simian Acquired Immunodeficiency Syndrome
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