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Cited by 129Marine Toxins and Detection MethodsMarine Plankton and BiogeochemistryAquatic Ecosystems and Phytoplankton Dynamics

The DOI matches its Crossref record; 43 of the 50 references it cites were found in a registry or an index.

Domoic acid: a fascinating marine toxin

Open access
Mos, Lizzy·2001·Environmental Toxicology and Pharmacology
DOI 10.1016/s1382-6689(00)00065-x
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Abstract

There are indications that toxic algal blooms are increasing because of pollution of coastal waters and worldwide shipping. This mini-review deals with the marine biotoxin domoic acid, also known as amnesic shellfish poison, and its main producing pennate diatom genus Pseudo-nitzschia (Bacillariophyceae). Besides contamination of seafood, these organisms have also been involved in human and marine wildlife mortality. The article aims to give an overview of all biological and environmental factors that should be considered when trying to evaluate a possible increase in toxic blooms of Pseudo-nitzschia spp. Pseudo-nitzschia blooms characteristically occur in a low light regime, at a time when the temperature is falling and at a wide range of salinities. Laboratory studies have shown that the production of domoic acid, a water-soluble amino acid, is related to silicon, phosphorus, nitrogen and trace metal (mainly iron) availability. Domoic acid has no known function in defence or primary metabolism; a role in excretion of excess photosynthetic energy or as a binding ligand for trace metals is suggested. The variability in domoic acid production by different Pseudo-nitzschia spp., or the presence of toxic and non-toxic strains of the same species, cannot be explained. The conclusion is drawn that an increase in toxic blooms of Pseudo-nitzschia spp. might be possible, especially because of the expected increase in nutrient availability from pollution and desert dust. Global warming may have an influence as well by lengthening the growth period for Pseudo-nitzschia, enlarging their global distribution and increasing the dust load through desertification.

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43 of 43 references verified0 citation errors · 0 not checkable

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Research works printed but not linked: 10

  1. Ajani, P., Lee, R., Pritchard, T, M. Krogh, 2000. Phytoplankton dynamics at a long-term coastal station off Sydney, Autralia. Proceedings of the Ninth Conference on Harmful Algal Blooms, Tasmania, abstract.
  2. Bates, S.S., Hiltz, M.F., C. Léger, 1999. Domoic acid toxicity of large new cells of Pseudo-nitzschia multiseries resulting from sexual production. In: Martin, J.L., K. Haya (Eds.), Proceedings of the Sixth Canadian Workshop on Harmful Marine Algae, pp. 21–26.
  3. Bates, S.S., Léger, C., Satchwell, M., G.L. Boyer, 2000. The effects of iron on domoic acid production by Pseudo-nitzschia multiseries. In: Hallegraeff, G.M. (Ed.), Proceedings of the Ninth Conference on Harmful Algal Blooms, Tasmania.
  4. Dahlsup, E., Aune, T., Tangen, K., 2000. Shellfish toxicity in Norway — experiences from regular monitoring, 1992–1999. In: Hallegraeff, G.M. (Ed.), Proceedings of the Ninth Conference on Harmful Algal Blooms, Tasmania.
  5. Hatfield, 1995, The fate of domoic acid in Dungeness crab (Cancer magister) as a function of processing, Journal of Shellfish Research, 14, 359
  6. Jak, R., 1998, Toxicant induced changes in zooplankton communities and consequences for phytoplankton development. Ph.D. Thesis, Amsterdam.
  7. Montresor, M., Sarno, D., Zingone, A., 2000. Can we peacefully live together with harmful phytoplankton? The case of the Gulf of Naples. Proceedings of the Ninth Conference on Harmful Algal Blooms, Tasmania, abstract.
  8. Prescott, L.M., Harley, J.P., Klein, D.A., 1996. Microbiology. Third edition, McGraw-Hill. New York, New York.
  9. Smith, 1990, Variation in domoic acid levels in Nitzschia species: implications for monitoring programs, Bulletin of the Aquaculture Association of Canada, 90-4, 27
  10. Wekell, 1994, The occurrence of domoic acid in razor clams (Siliqua patula), Dungeness crab (Cancer magister), and anchovies (Engraulis mordax), Journal of Shellfish Research, 13, 587

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Metadata

Authors
Mos, L.
Affiliations
Wageningen University & Research (NL)
Corresponding author
Mos, Lizzy
Venue
Environmental Toxicology and Pharmacology
Publisher
Elsevier BV
Published
2001-01
Volume
9
Issue
3
Pages
79-85
ISSN
1382-6689 (ISSN-L)
DOI
10.1016/s1382-6689(00)00065-x
OpenAlex
W2134695443
Cited by
129
References
50
Citations by year
2026: 2 · 2025: 2 · 2024: 1 · 2023: 4 · 2022: 7 · 2021: 4 · 2020: 4 · 2019: 4 · 2018: 9 · 2017: 7 · 2016: 5 · 2015: 10 · 2014: 8 · 2013: 6 · 2012: 6
FWCI
3.40
Type
journal article
Language
en
Open access
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Environmental Toxicology and Pharmacology (publishedVersion)
  • PubMed (publishedVersion)
  • Socio-Environmental Systems Modeling (acceptedVersion)
  • Data Archiving and Networked Services (DANS) (submittedVersion)
Topics
  • Physical Sciences › Environmental Science › Environmental Chemistry › Marine Toxins and Detection Methods
  • Physical Sciences › Earth and Planetary Sciences › Oceanography › Marine Plankton and Biogeochemistry
  • Physical Sciences › Environmental Science › Environmental Chemistry › Aquatic Ecosystems and Phytoplankton Dynamics
Keywords
domoic acid, Pseudo-nitzschia, harmful algal blooms, marine biotoxins, silicon limitation, trace metal availability, iron, nutrient availability, seafood contamination, desert dust, global warming, climate change

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