The DOI matches its Crossref record; 22 of the 22 references it cites were found in a registry or an index.
Burden and centralised treatment in Europe of rare tumours: results of RARECAREnet—a population-based study
Open accessAbstract
Background Rare cancers pose challenges for diagnosis, treatments, and clinical decision making. Information about rare cancers is scant. The RARECARE project defined rare cancers as those with an annual incidence of less than six per 100 000 people in European Union (EU). We updated the estimates of the burden of rare cancers in Europe, their time trends in incidence and survival, and provide information about centralisation of treatments in seven European countries.Methods We analysed data from 94 cancer registries for more than 2 million rare cancer diagnoses, to estimate European incidence and survival in 2000-07 and the corresponding time trends during 1995-2007. Incidence was calculated as the number of new cases divided by the corresponding total person-years in the population. 5-year relative survival was calculated by the Ederer-2 method. Seven registries (Belgium, Bulgaria, Finland, Ireland, the Netherlands, Slovenia, and the Navarra region in Spain) provided additional data for hospitals treating about 220 000 cases diagnosed in 2000-07. We also calculated hospital volume admission as the number of treatments provided by each hospital rare cancer group sharing the same referral pattern.Findings Rare cancers accounted for 24% of all cancers diagnosed in the EU during 2000-07. The overall incidence rose annually by 0.5% (99·8% CI 0·3-0·8). 5-year relative survival for all rare cancers was 48·5% (95% CI 48·4 to 48·6), compared with 63·4% (95% CI 63·3 to 63·4) for all common cancers. 5-year relative survival increased (overall 2·9%, 95% CI 2·7 to 3·2), from 1999-2001 to 2007-09, and for most rare cancers, with the largest increases for haematological tumours and sarcomas. The amount of centralisation of rare cancer treatment varied widely between cancers and between countries. The Netherlands and Slovenia had the highest treatment volumes.Interpretation Our study benefits from the largest pool of population-based registries to estimate incidence and survival of about 200 rare cancers. Incidence trends can be explained by changes in known risk factors, improved diagnosis, and registration problems. Survival could be improved by early diagnosis, new treatments, and improved case management. The centralisation of treatment could be improved in the seven European countries we studied.Funding The European Commission (Chafea).
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“However, translating the capabilities of current patch-based foundation models to address patient- and slide-level clinical challenges still remains complex due to the immense scale of gigapixel WSIs, compounded by the small size of patient cohorts in real-world evidence39–42, especially for rare diseases with limited training data43–45.”
From A multimodal whole-slide foundation model for pathology (2025) · cites this paper as [43]
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
International Classification of Diseases for Oncology
National Cancer Institute (2020) · Definitions · doi:10.32388/1bjeus · Cited by 3,810
Angelis, R. D., Sant, M., Coleman, M. P., Francisci, S., Baili, P., Pierannunzio, D., Trama, A., Visser, O. J., Brenner, H., Ardanáz, E., et al. (2013) · The Lancet Oncology · doi:10.1016/s1470-2045(13)70546-1 · Cited by 1,888
Self-citationWorldwide Thyroid-Cancer Epidemic? The Increasing Impact of Overdiagnosis
Vaccarella, S., Franceschi, S., Bray, F., Wild, C. P., Plummer, M., & Dal Maso, L. (2016) · New England Journal of Medicine · doi:10.1056/nejmp1604412 · Cited by 1,145
Rare cancers are not so rare: The rare cancer burden in Europe
Gatta, G., van der Zwan, J. M., Casali, P. G., Siesling, S., Tos, A. P. D., Kunkler, I. H., Otter, R., Licitra, L. F., Mallone, S., Tavilla, A., et al. (2011) · European Journal of Cancer · doi:10.1016/j.ejca.2011.08.008 · Cited by 813
Self-citationHuman papillomavirus related head and neck cancer survival: A systematic review and meta-analysis
O’Rorke, M. A., Ellison, M. V., Murray, L., Moran, M., James, J. A., & Anderson, L. A. (2012) · Oral Oncology · doi:10.1016/j.oraloncology.2012.06.019 · Cited by 422
Self-citationHeck, J. E., Berthiller, J., Vaccarella, S., Winn, D. M., Smith, E., Shangina, O., Schwartz, S. M., Purdue, M. P., Pilarska, A., Eluf‐Neto, J., et al. (2009) · International Journal of Epidemiology · doi:10.1093/ije/dyp350 · Cited by 385
Recent changes in the epidemiology of head and neck cancer
Curado, M. P., & Hashibe, M. (2009) · Current Opinion in Oncology · doi:10.1097/cco.0b013e32832a68ca · Cited by 354
Kantarjian, H. M., O'Brien, S. M., Jabbour, E. J., Garcia‐Manero, G., Quintás‐Cardama, A., Shan, J., Rios, M. B., Ravandi, F., Faderl, S. H., Kadia, T. M., et al. (2012) · Blood · doi:10.1182/blood-2011-08-358135 · Cited by 335
Sant, M., Minicozzi, P., Mounier, M., Anderson, L. A., Brenner, H., Holleczek, B., Marcos‐Gragera, R., Maynadié, M., Monnereau, A., Osca‐Gelis, G., et al. (2014) · The Lancet Oncology · doi:10.1016/s1470-2045(14)70282-7 · Cited by 292
Self-citationLepage, C., Capocaccia, R., Hackl, M., Lemmens, V., Molina‐Montes, E., Pierannunzio, D., Sant, M., Trama, A., Faivre, J., Hackl, M., et al. (2015) · European Journal of Cancer · doi:10.1016/j.ejca.2015.07.034 · Cited by 149
Self-citation
Research works printed but not linked: 1
- Ederer, 1961, The relative survival: a statistical methodology, Natl Cancer Inst Monogr, 6, 101
Cited by
Sorted by citations
Items 201–300 of 517
Management of recurrent retroperitoneal sarcomas
Siew, C. C. H., Cardona, K., & van Houdt, W. J. (2022) · European Journal of Surgical Oncology · doi:10.1016/j.ejso.2022.06.008 · Cited by 8
van Oss, A., Duijts, S. F. A., van Laarhoven, H. W. M., Kuip, E. J. M., Raijmakers, N. J. H., & Brom, L. (2023) · Journal of Cancer Survivorship · doi:10.1007/s11764-022-01323-8 · Cited by 8
Challenges and opportunities in rare cancer research in China
Xue, J., & Lyu, Q. (2023) · Science China Life Sciences · doi:10.1007/s11427-023-2422-x · Cited by 8
Pestana, R. C., David, B. B. L., de Camargo, V. P., Munhoz, R. R., de Mello, C. A. L., Donna, M. L. G., Varas, J. C. H., Zapata, M., Martins, C. L. C., Chacon, M. R., et al. (2024) · The Lancet Regional Health - Americas · doi:10.1016/j.lana.2023.100671 · Cited by 8
Progress in histology specific treatments in soft tissue sarcoma
Redaelli, S., Merlini, A., Khan, M. U., & Gronchi, A. (2024) · Expert Review of Anticancer Therapy · doi:10.1080/14737140.2024.2384584 · Cited by 8
Epidemiology of malignant brain tumors in Genova, Italy. 1993–2017
Fròsina, G., Casella, C., Puppo, A., Marani, E., Campanella, D., Boni, L., & Fontana, V. (2024) · Scientific Reports · doi:10.1038/s41598-024-79170-z · Cited by 8
Self-citationDrug repurposing for cancer therapy—an introduction
Pantziarka, P., Meheus, L., Rombauts, K., Vandeborne, L., & Bouche, G. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-819668-7.00001-4 · Cited by 9
Chiappetta, M., Lococo, F., Sassorossi, C., Aigner, C., Plönes, T., Raemdonck, D. E. V., Vanluyten, C., Schil, P. E. V., Agrafiotis, A. C., Guerrera, F., et al. (2024) · Annals of Surgical Oncology · doi:10.1245/s10434-024-15194-z · Cited by 8
Pathological discrepancies in the diagnosis of thymic epithelial tumors: the Tallinn-Lyon experience
Oselin, K., Girard, N., Lepik, K., Adamson-Raieste, A., Vanakesa, T., Almre, I., Leismann, T., & Chalabreysse, L. (2019) · Journal of Thoracic Disease · doi:10.21037/jtd.2018.12.123 · Cited by 8
Targeted Therapies in Rare Brain Tumours
Bruno, F., Pellerino, A., Bertero, L., Soffietti, R., & Rudà, R. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22157949 · Cited by 8
Lipplaa, A., van der Wal, R. J. P., Krol, A. D. G., Peul, W. C., Bovée, J. V. M. G., & Gelderblom, H. A. J. (2024) · Cancer Epidemiology · doi:10.1016/j.canep.2024.102527 · Cited by 7
Prognosis and tumor microenvironment in pseudohypoxic pheochromocytoma/paraganglioma
Ohmoto, A., Shigematsu, Y., Saito, R., Dobashi, A., Fujiwara, Y., Togashi, Y., Yonese, J., Inamura, K., & Takahashi, S. (2024) · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin · doi:10.1007/s00428-024-04009-x · Cited by 7
Mata-Martínez, P., Celada, L., Cueto, F. J., María, G. S. D. S., Fernández, J., Terrón‐Arcos, V., Valdés, N., Moreira, V. G., Toro, M., López‐Collazo, E., et al. (2025) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-025-03337-3 · Cited by 7
Soleimani, M., Ghazisaeedi, M., Ayyoubzadeh, S. M., & Jalilvand, A. (2025) · Archives of Public Health · doi:10.1186/s13690-025-01584-6 · Cited by 8
The Role of Positron Emission Tomography Imaging in Primary Bone Tumours: A Narrative Review
Hassan, S., Suvarna, R., Uldin, H., Hussein, M. A. M., & Botchu, R. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14082624 · Cited by 7
Aigner, F., Siegel, R., Werner, R. N., Eßer, S., Oette, M., Weyandt, G. H., Kahlke, V., Saeed, A., Turina, M., Mosthaf, F., et al. (2021) · coloproctology · doi:10.1007/s00053-021-00530-8 · Cited by 7
Radiotherapy in the management of rare gastrointestinal cancers: A systematic review
Bellefkih, F. Z., Benchakroun, N., Lalya, I., Amaoui, B., Kacemi, H. E., Acharki, A., Hfid, M. E., Mazghi, A. E., Chekrine, T., Bouchbika, Z., et al. (2023) · Cancer/Radiothérapie · doi:10.1016/j.canrad.2023.06.010 · Cited by 7
Cercato, M. C., Onesti, C. E., Vari, S., Maggi, G., Faltyn, W., Ceddia, S., Terrenato, I., Scarinci, V., Servoli, F., Cenci, C., et al. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12237218 · Cited by 7
Hussein, M. A. M., Gupta, H., Ahuja, A., & Thaker, S. (2024) · Clinical Radiology · doi:10.1016/j.crad.2024.08.023 · Cited by 7
Global, regional, and national burden of soft tissue and extraosseous sarcomas from 1990 to 2021
Chen, C., Wang, C., Li, S., Zheng, X., & Yang, Y. (2024) · Preventive Medicine Reports · doi:10.1016/j.pmedr.2024.102903 · Cited by 7
Siegel, R., Werner, R. N., Koswig, S., Gaskins, M. D., Rödel, C. M., & Aigner, F. (2021) · Deutsches Ärzteblatt international · doi:10.3238/arztebl.m2021.0027 · Cited by 7
Lived experience of people with adrenocortical carcinoma and associated adrenal insufficiency
Yeoh, P., Czuber‐Dochan, W., Aylwin, S. J. B., & Sturt, J. A. (2022) · Endocrinology Diabetes & Metabolism · doi:10.1002/edm2.341 · Cited by 7
Bernatz, S., Böth, I., Ackermann, J., Burck, I., Mahmoudi, S., Lenga, L., Martin, S. S., Scholtz, J., Koch, V., Grünewald, L. D., et al. (2023) · BMC Medical Imaging · doi:10.1186/s12880-023-01034-1 · Cited by 7
Aldehyde Dehydrogenase, a Therapeutic Target in Chordoma: Analysis in 3D Cellular Models
Locquet, M.-A., Dechaume, A.-L., BERCHARD, P., Abbes, L., Pissaloux, D., Tirode, F., Ramos, I., Bedoucha, J., Valantin, J., Karanian, M., et al. (2021) · Cells · doi:10.3390/cells10020399 · Cited by 7
The loop between inflammation and late systemic toxicity in head and neck cancer survivors
Mascagni, I., & Bossi, P. (2025) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2025.104781 · Cited by 6
Thymic epithelial tumors: what’s new and what’s next?
Imbimbo, M., Salfi, G., Borgeaud, M., Ottaviano, M., Froesch, P., Bouchaab, H., Cafarotti, S., & Addeo, A. (2025) · ESMO rare cancers. · doi:10.1016/j.esmorc.2025.100024 · Cited by 6
Renner, M., Oleś, M., Paramasivam, N., Heilig, C. E., Schneider, A., Modugno, C., Herremans, C., Hüllein, J., Hutter, B., Erkut, C., et al. (2026) · Nature Communications · doi:10.1038/s41467-026-71636-0 · Cited by 6
Patel, S. P., Othus, M. K. D., Chae, Y. K., Azenkot, T., Alviz, C., Threlkel, S. A., Haymaker, C., STREICHER, H. Z., Magner, C. M., Chen, H. X., et al. (2026) · Annals of Oncology · doi:10.1016/j.annonc.2026.04.004 · Cited by 6
A Successful Chemoembolization of a Retroperitoneal Soft Tissue Sarcoma: A Case Report
Filho, W. J. D., Uchiyama, A. A. T., da Silva, C. M., Lopes, L. M. D., Baccarin, A. L. D. C., Fina, B. D., dos Santos, R. V., & Galastri, F. L. (2021) · Case Reports in Oncology · doi:10.1159/000520381 · Cited by 6
EU Country Cancer Profile: Slovenia 2023
OECD (2023) · Country cancer profiles · doi:10.1787/cd631ba0-en · Cited by 6
Sugiyama, H., Konda, M., Saika, K., & Matsuda, T. (2024) · Cancer Science · doi:10.1111/cas.16176 · Cited by 6
Liu, W., Zou, B., Tang, M., Li, X., Huang, M., Chen, W., & Miao, C. (2022) · Annals of Translational Medicine · doi:10.21037/atm-22-4222 · Cited by 6
Yanagisawa, N., Matsuoka, M., Onodera, T., Iwasaki, K., Hamasaki, M., Ebata, T., Hosokawa, Y., Kondo, E., & Iwasaki, N. (2024) · Journal of Orthopaedics · doi:10.1016/j.jor.2024.03.017 · Cited by 6
Epidemiologie ausgewählter endokriner Tumoren in Deutschland
Kraywinkel, K. (2018) · Der Onkologe · doi:10.1007/s00761-018-0333-z · Cited by 6
Incidence of rare cancers in the city of São Paulo, Brazil
Bustamante-Teixeira, M. T., Latorre, M. D. R. D. O., Guerra, M. R., Tanaka, L. F., Botta, L., Trama, A., & Gatta, G. (2019) · Tumori Journal · doi:10.1177/0300891618821039 · Cited by 6
Self-citationCommunication strategies for rare cancers: a systematic review protocol
Bell, C., Kerr, K., Moore, K., McShane, C. M., Anderson, L. A., McKnight, A. J., & McAneney, H. (2019) · Systematic Reviews · doi:10.1186/s13643-019-1017-5 · Cited by 6
Self-citationRare cancers of unknown etiology: lessons learned from a European multi-center case–control study
Lynge, E., Kærlev, L., Olsen, J., Sabroe, S., Afonso, N., Ahrens, W., Eriksson, M., Merletti, F., Morales-Suarez-Varelas, M., Stengrēvics, A., et al. (2020) · European Journal of Epidemiology · doi:10.1007/s10654-020-00663-y · Cited by 6
Lauri, A., Fasano, G., Venditti, M., Dallapiccola, B., & Tartaglia, M. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.642235 · Cited by 7
Rare cancers and cancer of unknown primary: Here's what you should know!
Duijts, S. F. A., & van der Zwan, J. M. (2021) · European Journal of Cancer Care · doi:10.1111/ecc.13508 · Cited by 6
Trends in practice patterns and outcomes: A decade of sarcoma care in the United States
Song, Y., Ecker, B. L., Tang, R. B., Maggino, L., Roses, R. E., DeMatteo, R. P., Fraker, D. L., & Karakousis, G. C. (2019) · Surgical Oncology · doi:10.1016/j.suronc.2019.05.018 · Cited by 6
Werner, R. N., Gaskins, M. D., Dressler, C., Nast, A., Schaefer, C., Aigner, F., & Siegel, R. (2020) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2020.09.026 · Cited by 6
Salmerón, D., Botta, L., Martı́nez, J. M., Trama, A., Gatta, G., Borràs, J. M., Capocaccia, R., Clèries, R., & for the Information Network on Rare Cancers (RARECARENet) Working Group (2021) · American Journal of Epidemiology · doi:10.1093/aje/kwab262 · Cited by 6
Self-citationMalignant pleural mesothelioma: new guidelines make us stronger for defeating this disease
Remón, J., Hendriks, L. E. L., & Bironzo, P. (2021) · Annals of Oncology · doi:10.1016/j.annonc.2021.11.019 · Cited by 6
Retegui, G., Etxeberria, J., & Ugarte, M. D. (2024) · Environmental and Ecological Statistics · doi:10.1007/s10651-024-00630-w · Cited by 5
Oestreich, L., Mumm, F., Pichler, T., Boukovala, M. A., Colonna, V., Gioia, D. D., Fey, T., Heinemann, V., Hinneburg, J., Lühnen, J., et al. (2025) · European Journal of Cancer · doi:10.1016/j.ejca.2025.115602 · Cited by 5
Retroperitoneal and Mesenteric Liposarcomas
Siew, C. C. H., Apte, S. S., Baia, M., Gyorki, D. E., Ford, S., & van Houdt, W. J. (2022) · Surgical Oncology Clinics of North America · doi:10.1016/j.soc.2022.03.005 · Cited by 5
Soft Tissue Reconstruction of the Posterior Trunk after Tumor Excision: A Surgical Algorithm
Innocenti, M., Mori, F., Pedrini, F. A., Salmaso, L., Gennaro, A., & Sassu, P. (2023) · Cancers · doi:10.3390/cancers15041214 · Cited by 5
Ahmed, S., Wedekind, M. F., Rivero, J. D., Raygada, M. J., Lockridge, R., Glod, J. W., Flowers, C., Thomas, B., Bernstein, D. B., Kapustina, O. B., et al. (2023) · Cancer Research Communications · doi:10.1158/2767-9764.crc-23-0247 · Cited by 5
Sinonasal cancer incidence in Lombardy, Italy, 2008–20
Consonni, D., Stoppa, G., Binazzi, A., Dallari, B., Stella, S., Rugarli, S., Trobbiani, C., Biggeri, A., Catelan, D., & Mensi, C. (2024) · Occupational Medicine · doi:10.1093/occmed/kqae034 · Cited by 5
Weadick, C. S., Goggin, C., Keogh, R. J., Murphy, J., Feeley, L., Bennett, M. W., O’Reilly, S., Redmond, H. P., Kelly, J., O’Mahony, D., et al. (2024) · World Journal of Oncology · doi:10.14740/wjon1863 · Cited by 5
Nachtsheim, L., Möller, L., Oesterling, F., Kajueter, H., Stang, A., Hieggelke, L., Abing, H., Sharma, J. S., Klußmann, J. P., Mayer, M., et al. (2024) · Cancer Epidemiology · doi:10.1016/j.canep.2024.102684 · Cited by 5
Kostadinov, K. R., Iskrov, G. G., Мусурлиева, Н., & Stefanov, R. S. (2025) · Journal of Cancer Policy · doi:10.1016/j.jcpo.2025.100570 · Cited by 5
Landscape of ultra-rare sarcomas: a nationwide study for epidemiology and prognosis
Shimada, E., Nakagawa, M., Endo, M., Yokoyama, N., Nabeshima, A., Fujiwara, T., Kawai, A., & Nakashima, Y. (2025) · ESMO Open · doi:10.1016/j.esmoop.2025.105097 · Cited by 5
RareNet: a deep learning model for rare cancer diagnosis
Shao, D., Addagudi, S., Cowles, J., Jain, A., D'Souza, L., Gore, S., & Azad, R. K. (2025) · Scientific Reports · doi:10.1038/s41598-025-08829-y · Cited by 5
Calì, C., Amodio, R., Fabiano, S., Gatta, G., Maule, M. M., Perotti, V., Savoia, F., Sessa, M., Tittarelli, A., Mazzucco, W., et al. (2025) · Cancer Epidemiology · doi:10.1016/j.canep.2025.102895 · Cited by 5
Self-citationParikh, K., Hendriks, L. E. L., Bironzo, P., & Remón, J. (2021) · Cancer Treatment Reviews · doi:10.1016/j.ctrv.2021.102250 · Cited by 5
Alcántara-Quintana, L. E., López-Mendoza, C. M., Rodríguez‐Aguilar, M., Medellín-Castillo, N. A., Mizaikoff, B., Flores‐Ramírez, R., Galván-Romero, V. S., & de León-Martínez, L. D. (2022) · Analytical Chemistry · doi:10.1021/acs.analchem.2c02439 · Cited by 5
Prades, J., Trama, A., Casali, P. G., Emile, J., Gaspar, N., Janavičius, R., Jančiauskienė, R., Karjalainen, S., Kopečková, K., Pylkkänen, L. H., et al. (2022) · European Journal of Public Health · doi:10.1093/eurpub/ckac166 · Cited by 5
Self-citationVaamonde-Martín, R. J., Ballesta-Ruíz, M., Sánchez-Gil, A., Fernández, J. Á., Martínez‐Barba, E., Martínez-García, J., Gatta, G., & Chirlaque, M. (2023) · Cancers · doi:10.3390/cancers15112994 · Cited by 5
Self-citationSağnıç, S., Karadağ, C., Tuncer, H. A., Doğan, S., & Şimşek, T. (2023) · Journal of Turkish Society of Obstetric and Gynecology · doi:10.4274/tjod.galenos.2023.98036 · Cited by 5
Hinneburg, J., Zacher, S., Berger‐Höger, B., Berger, K., Kratzer, V., Steckelberg, A., Lühnen, J., & TARGET Group (2023) · JMIR Research Protocols · doi:10.2196/49731 · Cited by 5
Proposal for a New Classification of Rare Cancers Adopting Updated Histological Tumor Types
Rikitake, R., Yatabe, Y., Yamamoto, Y., Shimoi, T., Iwata, S., Goto, Y., Mizushima, Y., Kawai, A., & Higashi, T. (2025) · Pathology International · doi:10.1111/pin.70021 · Cited by 5
Nicolai, N., Biasoni, D., Catanzaro, M. A., Colecchia, M., Trama, A., Hackl, M., Eycken, E. V., Henau, K., Dimitrova, N., Šekerija, M., et al. (2018) · European Journal of Surgical Oncology · doi:10.1016/j.ejso.2018.02.006 · Cited by 5
Self-citationClinical performance in ERN eUROGEN for penile, testicular, adrenal and soft tissue cancers
Ashley, S. L., Shilhan, D., Battye, M., Meyer, C. P., Mancini, M., Ayres, B. E., Muneer, A., Albersen, M., Feitz, W., Langenhuijsen, J. F., et al. (2021) · European Journal of Surgical Oncology · doi:10.1016/j.ejso.2021.11.014 · Cited by 5
Druggable gene alterations in Japanese patients with rare malignancy
Ohmoto, A., Hayashi, N., Fukada, I., Yamazaki, M., Yunokawa, M., Kasuga, A., Shinozaki, E., Ueki, A., Tonooka, A., Takeuchi, K., et al. (2022) · Neoplasia · doi:10.1016/j.neo.2022.100834 · Cited by 5
Barber, P. R., Mustapha, R., Flores‐Borja, F., Alfano, G., Ng, K., Weitsman, G. E., Dolcetti, L., Suwaidan, A. A., Wong, F., Vicencio, J. M., et al. (2022) · eLife · doi:10.7554/elife.73288 · Cited by 5
Rare tumors: a blue ocean of investigation
Wang, S., Ma, P., Jiang, N., Jiang, Y., Yu, Y., Fang, Y., Miao, H., Huang, H., Tang, Q., Cui, D., et al. (2023) · Frontiers of Medicine · doi:10.1007/s11684-023-0984-z · Cited by 5
Career and Financial Situation of Patients Diagnosed with Soft Tissue Sarcomas
Laros, N., Sungu-Winkler, K. T., Gutermuth, S., Wartenberg, M., Hohenberger, P., Seifart, U., & Kasper, B. (2020) · Oncology Research and Treatment · doi:10.1159/000509518 · Cited by 5
Necchi, A., Vullo, S. L., Secondino, S., Rosti, G., Badoglio, M., Giannatempo, P., Raggi, D., Lanza, F., Chabannon, C., Bonini, C., et al. (2018) · Bone Marrow Transplantation · doi:10.1038/s41409-017-0079-z · Cited by 5
The Burden of Rare Cancers in North America.
Hofer, B. M., Weir, H. K., Eckstrand, A., Musonda, K. L., & Sherman, R. (2023) · PubMed Central · Cited by 4
Padilla, C. S., de Heus, E., Reuvers, M. J. P., Schrieks, M., Engelen, V., Grünhagen, D. J., Tesselaar, M. E. T., van der Graaf, W. T. A., Duijts, S. F. A., & Husson, O. (2024) · Supportive Care in Cancer · doi:10.1007/s00520-024-08998-y · Cited by 4
Bone sarcomas and cancer predisposition syndromes
Tlemsani, C., Bougeard, G., Gauthier‐Villars, M., Denizeau, P., Winter, S., Michot, C., Baujat, G., Paillerets, B. B., de Beaumais, T. A., Rouchaud, A., et al. (2025) · Bulletin du Cancer · doi:10.1016/j.bulcan.2024.10.014 · Cited by 4
Sánchez, H. M., Cañete, A., Mateos, D. S., Benavent, N., Fernández, J., Robles, A. S., Martin, C., Vázquez, J. G., Salom, M., Macián, A. M., et al. (2025) · Pediatric Radiology · doi:10.1007/s00247-025-06410-3 · Cited by 4
Zhao, X., Lin, H., Zeng, B., Zhou, R., Ma, L., Liu, B., Shan, Q., & Wu, T. (2026) · Frontiers in Oncology · doi:10.3389/fonc.2025.1686356 · Cited by 4
Precision oncology in rare tumors: Have the orphans been adopted?
Mechahougui, H., Friedlaender, A., Görgülü, K., Tsantoulis, P. K., Illert, A. L., Subbiah, V., Wahida, A., & Kurzrock, R. (2026) · Med · doi:10.1016/j.medj.2025.100958 · Cited by 4
Bazzocchi, A., Guglielmi, G., & Gómez, M. P. A. (2023) · Magnetic Resonance Imaging Clinics of North America · doi:10.1016/j.mric.2023.01.004 · Cited by 4
Prognostic factors of sarcomas occurring in bone and joint: A SEER based study
Zhou, H., He, S., Zhang, D., Wang, J., Yang, X., Jiao, J., Xu, W., Yang, J. M., & Xiao, J. (2023) · Medicine · doi:10.1097/md.0000000000034231 · Cited by 4
Killian, M. E., Barry, T., Larsen, C., & Alsidawi, S. (2023) · European Heart Journal - Case Reports · doi:10.1093/ehjcr/ytad546 · Cited by 4
Current prospects of hereditary adrenal tumors: towards better clinical management
Ohmoto, A., Hayashi, N., Takahashi, S., & Ueki, A. (2024) · Hereditary Cancer in Clinical Practice · doi:10.1186/s13053-024-00276-6 · Cited by 4
Wen, W., Zhao, S., Jiang, Y., Ou, C., Guo, C., Jia, Z., Li, J., Huang, Y., Xu, H., Pu, P., et al. (2024) · Genetics in Medicine Open · doi:10.1016/j.gimo.2024.101899 · Cited by 4
Rare tumor list provide vast opportunities for novel drug development in China
Zheng, R., Wang, S., Zhao, G., Wei, W., & Li, N. (2024) · 中国科学通报：英文版 · doi:10.1016/j.scib.2024.11.017 · Cited by 4
Trama, A., Cuccaro, F., Damiani, D., Bernasconi, A., Panzuto, F., Fazio, N., Carone, S., Monaco, M. G. B. L., Bruni, R., Caldarella, A., et al. (2025) · Tumori Journal · doi:10.1177/03008916251317128 · Cited by 4
Self-citationPrognostic gene expression signatures for HPV-negative head and neck squamous cell carcinoma
Cavalieri, S., Brakenhoff, R. H., Leemans, C. R., Hoebers, F. J. P., Poli, T., Scheckenbach, K., Iacovelli, N. A., Franceschini, M., Orlandi, E. M., Licitra, L. F., et al. (2025) · Radiotherapy and Oncology · doi:10.1016/j.radonc.2025.110900 · Cited by 4
Liontos, M., Kastritis, E., Markellos, C., Migkou, M., Eleftherakis-Papaiakovou, E., Koutsoukos, K., Gavriatopoulou, M., Zagouri, F., Ψαλτοπούλου, Θ., Terpos, E., et al. (2021) · Cancers · doi:10.3390/cancers13040763 · Cited by 4
Maître, E., & Troussard, X. (2022) · ONCOLOGIE · doi:10.32604/oncologie.2022.021490 · Cited by 4
Self-citationBarcellini, A., Dominoni, M., Gardella, B., Mangili, G., & Orlandi, E. M. (2022) · International Journal of Gynecological Cancer · doi:10.1136/ijgc-2022-003686 · Cited by 4
van Kooten, J. P., de Gooijer, C. J., von der Thüsen, J. H., Brandt‐Kerkhof, A. R. M., Albers, A. G. J., Lahaye, M. J., Monkhorst, K., Burgers, J. A., Aerts, J. G. J. V., Verhoef, C. K., et al. (2022) · European Journal of Surgical Oncology · doi:10.1016/j.ejso.2022.10.003 · Cited by 4
Thoenissen, P., Najafi, R., Sader, R., & Ghanaati, S. (2023) · Journal of Cranio-Maxillofacial Surgery · doi:10.1016/j.jcms.2023.12.002 · Cited by 4
Essouma, M., Soh, D. M., Temgoua, M. N., Gobina, R. M., Nono, A., Atenguena, E., Mahamat, M., & Ashuntantang, G. E. (2019) · Journal of Medical Case Reports · doi:10.1186/s13256-019-2225-2 · Cited by 4
Liu, Y., Pan, M., Lu, T., Li, Y., Yu, D., Wang, Z., & Hu, G. (2022) · Journal of Oncology · doi:10.1155/2022/1205353 · Cited by 4
Tahara, S., de Faria, F. C. C., Sarchet, P., Calore, F., Sharick, J. T., Leight, J. L., Casadei, L., & Pollock, R. E. (2023) · Human Cell · doi:10.1007/s13577-023-00865-y · Cited by 4
What could be a cancer mission objective if we join our forces in the fight against cancer?
Philip, T. O., Karjalainen, S., Lorenzo, F. D., Apostolidis, K., Lombardo, C., Nilbert, M. C., Lacombe, D., Poortmans, P. M., Albreht, T., Kearns, P. R., et al. (2019) · Tumori Journal · doi:10.1177/0300891619886351 · Cited by 4
Analkarzinom, L., Aigner, F., Werner, R. N., & Siegel, R. (2021) · coloproctology · doi:10.1007/s00053-021-00522-8 · Cited by 4
Challenges of diagnosing rare cancers in primary care
Moore, S. F., Abel, G., & Mounce, L. T. A. (2024) · British Journal of General Practice · doi:10.3399/bjgp24x738789 · Cited by 4
de Heus, E., Duijts, S. F. A., van der Zwan, J. M., van Herpen, C. M. L., Merkx, M. A. W., Rutherford, M. J., & Soerjomataram, I. (2024) · Cancer Epidemiology · doi:10.1016/j.canep.2024.102706 · Cited by 3
Weber, M., Fuchs, D., Pöschel, A., Beebe, E., Garajovà, Z., Jarosch, A., Kunz, L., Wolski, W., Opitz, L., Guscetti, F., et al. (2024) · Neoplasia · doi:10.1016/j.neo.2024.101104 · Cited by 3
Pluta, P., Giza, A., Kolenda, M., Fendler, W. M., Braun, M., Chudobiński, C., Chałubińska‐Fendler, J., Araszkiewicz, M., Loga, K., Lembas, L., et al. (2020) · Archives of Medical Science · doi:10.5114/aoms.2020.100637 · Cited by 3
Measuring the impact of rare diseases in Tasmania, Australia
Scanlon, P., Ridler, G., Say, G., Kellett, M., Charlesworth, J., Neil, A. L., Dickinson, J. L., Burdon, K. P., Jose, M., & Wallis, M. (2024) · Orphanet Journal of Rare Diseases · doi:10.1186/s13023-024-03343-2 · Cited by 3
Benvenuti, G., Marzi, S., Vidiri, A., Baldi, J., Ceddia, S., Riva, F., Covello, R., Terrenato, I., & Anelli, V. (2024) · La radiologia medica · doi:10.1007/s11547-024-01921-9 · Cited by 3
Li, J., Jiang, N., Zhang, J., Sun, W., Wang, Z., Sun, L., & Wang, X. (2025) · European Journal of Radiology · doi:10.1016/j.ejrad.2024.111912 · Cited by 3
Metadata
- Authors
- Gatta, G., Capocaccia, R., Botta, L., Mallone, S., De Angelis, R., Ardanaz, E., Comber, H., Dimitrova, N., Leinonen, M. K., Siesling, S., van der Zwan, J. M., Van Eycken, L., Visser, O., Žakelj, M. P., Anderson, L. A., Bella, F., Kaire, I., Otter, R., Stiller, C. A., Trama, A., Hackl, M., Henau, K., Van Damme, N., Valerianova, Z., Sekerija, M., Dušek, L., Mägi, M., Paapsi, K., Malila, N., Velten, M., Troussard, X., Bouvier, V., Guizard, A.-V., Bouvier, A.-M., Arveux, P., Maynadié, M., Woronoff, A.-S., Robaszkiewicz, M., Baldi, I., Monnereau, A., Tretarre, B., Colonna, M., Molinié, F., Bara, S., Schvartz, C., Lapôtre-Ledoux, B., Grosclaude, P., Stabenow, R., Luttmann, S., Nennecke, A., Engel, J., SchubertFritschle, G., Heidrich, J., Holleczek, B., Jónasson, J. G., Clough-Gorr, K., Mazzoleni, G., Giacomin, A., Sardo, A. S., Barchielli, A., Serraino, D., Collarile, P., Pannozzo, F., Ricci, P., Autelitano, M., Spagnoli, G., Fusco, M., Usala, M., Vitale, F., Michiara, M., Tumino, R., Mangone, L., Falcini, F., Ferretti, S., Filiberti, R. A., Marani, E., Caiazzo, A. L., Iannelli, A., Sensi, F., Piffer, S., Gentilini, M., Madeddu, A., Colanino, A. Z., Maspero, S., Candela, P., Stracci, F., Tagliabue, G., Rugge, M., Baili, P., Minicozzi, P., Sant, M., Tereanu, C., Francisci, S., Tavilla, A., Pierannunzio, D., Rossi, S., Santaquilani, M., Knijn, A., Pildava, S., Smailyte, G., Calleja, N., Agius, D., Johannesen, T. B., Rachtan, J., Gózdz, S., Blaszczyk, J., Kepska, K., Lacerda, G. F. D., Bento, M. J., Miranda, A., Diba, C. S., Žagar, T., Almar, E., Larrañaga, N., Munain, A. L. D., Torrella-Ramos, A., García, J. M. D., Marcos-Gragera, R., Sanchez, M. J., Navarro, C., Salmeron, D., Moreno-Iribas, C., Galceran, J., Carulla, M., Mousavi, M., Bouchardy, C., Ess, S. M., Bordoni, A., Konzelmann, I., Rashbass, J., Gavin, A., Brewster, D. H., Huws, D. W., Ho, V. K., & Benhamou, E.
- Affiliations
- Fondazione IRCCS Istituto Nazionale dei Tumori (IT)
- Istituto Superiore di Sanità (IT)
- National Cancer Registry (IE)
- Finnish Cancer Registry (FI)
- Netherlands Comprehensive Cancer Organisation (NL)
- Institute of Oncology Ljubljana (SI)
- Queen's University Belfast (GB)
- Policlinico Universitario di Catania (IT)
- Institut Scientifique de Santé Publique (BE)
- Public Health England (GB)
- Instituto de Salud Pública de Navarra (ES)
- Corresponding author
- Gatta, Gemma
- ORCID
- Gatta, Gemma
- Capocaccia, Riccardo
- Botta, Laura
- Mallone, Sandra
- Comber, Harry
- Dimitrova, Nadya
- Leinonen, Maarit K
- Siesling, Sabine
- Visser, Otto
- Anderson, Lesley A
- Stiller, Charles A
- Trama, Annalisa
- Dušek, Ladislav
- Mägi, Margit
- Paapsi, Keiu
- Malila, Nea
- Troussard, Xavier
- Guizard, Anne-Valérie
- Bouvier, Anne-Marie
- Arveux, Patrick
- Maynadié, Marc
- Woronoff, Anne-Sophie
- Robaszkiewicz, Michel
- Baldi, Isabelle
- Monnereau, Alain
- Colonna, Marc
- Molinié, Florence
- Grosclaude, Pascale
- Luttmann, Sabine
- Nennecke, Alice
- Mazzoleni, Guido
- Serraino, Diego
- Vitale, Francesco
- Tumino, Rosario
- Falcini, Fabio
- Ferretti, Stefano
- Filiberti, Rosa Angela
- Piffer, Silvano
- Tagliabue, Giovanna
- Rugge, Massimo
- Baili, Paolo
- Minicozzi, Pamela
- Sant, Milena
- Francisci, Silvia
- Tavilla, Andrea
- Pierannunzio, Daniela
- Rossi, Silvia
- Santaquilani, Mariano
- Knijn, Arnold
- Pildava, Santa
- Calleja, Neville
- Rachtan, Jadwiga
- Miranda, Ana
- Žagar, Tina
- Almar, Enrique
- Larrañaga, Nerea
- García, José María Díaz
- Navarro, Carmen
- Bouchardy, Christine
- Ess, Silvia M.
- Gavin, Anna
- Brewster, David H
- Huws, Dyfed Wyn
- Ho, Vincent KY
- Venue
- The Lancet Oncology
- Publisher
- Elsevier BV
- Published
- 2017-08
- Volume
- 18
- Issue
- 8
- Pages
- 1022-1039
- ISSN
- 1470-2045 (ISSN-L)
- OpenAlex
- W2729284305
- Cited by
- 516
- References
- 22
- Citations by year
- 2026: 60 · 2025: 82 · 2024: 81 · 2023: 71 · 2022: 64 · 2021: 52 · 2020: 47 · 2019: 27 · 2018: 24 · 2017: 6
- FWCI
- 12.46
- Type
- journal article
- Language
- en
- Update notices
- erratum (2017-08-01)
- Open access
- bronze
- doi.org
- Locations
- The Lancet Oncology (publishedVersion)
- PubMed (publishedVersion)
- OAR@UM (University of Malta) (submittedVersion, other-oa)
- HAL (submittedVersion)
- Nova Science Publishers (Nova Science Publishers, Inc.) (submittedVersion)
- Research Portal (Queen's University Belfast) (submittedVersion, other-oa)
- Institutional Research Information System University of Ferrara (University of Ferrara) (submittedVersion, cc-by)
- Padua Research Archive (University of Padova) (submittedVersion)
- Funders
- European Commission through the Consumers, Health, Agriculture and Food Executive Agency (Grant No. 2000111201)
- Topics
- Health Sciences › Medicine › Oncology › Global Cancer Incidence and Screening
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advances in Oncology and Radiotherapy
- Health Sciences › Medicine › Oncology › COVID-19 and healthcare impacts
- Keywords
- rare tumor, cancer incidence, cancer survival, cancer registry, incidence trends, sarcoma, Europe, referral patterns, healthcare resource allocation, cancer care costs
- MeSH terms
- Cancer Care Facilities, Delivery of Health Care, Europe, Female, Hospitalization, Humans, Male, Neoplasms, Registries, Incidence, Survival Rate, Rare Diseases
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
