The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Genetic susceptibility to infectious diseases: big is beautiful, but will bigger be even better?
Open accessAbstract
Genetic epidemiology, including twin studies, provides robust evidence that genetic variation in human populations contributes to susceptibility to infectious disease. One of the major limitations of studies that attempt to identify the genes and mechanisms that underlie this susceptibility has been lack of power caused by small sample size. With the development of novel technologies, burgeoning information on the human genome, the HapMap project, and human genetic diversity, we are at the beginning of a new era in the study of the genetics of complex diseases. This review looks afresh at the epidemiological evidence that supports a role for genetics in susceptibility to infectious disease, examines the somewhat limited achievements to date, and discusses current advances in methodology and technology that will potentially lead to translational data in the future.
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Cites
Complement factor H polymorphism in age-related macular degeneration
Klein, R. J., Zeiss, C., Chew, E. Y., Tsai, J.-Y., Sackler, R. S., Haynes, C., Henning, A. K., SanGiovanni, J. P., Mane, S. M., Mayne, S. T., et al. (2005) · Science · doi:10.1126/science.1109557 · Cited by 4,492
Complement factor H polymorphism and age-related macular degeneration
Edwards, A. O., Ritter, R., Abel, K. J., Manning, A., Panhuysen, C., & Farrer, L. A. (2005) · Science · doi:10.1126/science.1110189 · Cited by 2,449
Complement factor H variant increases the risk of age-related macular degeneration
Haines, J. L., Hauser, M. A., Schmidt, S., Scott, W. K., Olson, L. M., Gallins, P., Spencer, K. L., Kwan, S. Y., Noureddine, M., Gilbert, J. R., et al. (2005) · Science · doi:10.1126/science.1110359 · Cited by 2,424
Detecting recent positive selection in the human genome from haplotype structure
Sabeti, P. C., Reich, D. E., Higgins, J. M., Levine, H. Z. P., Richter, D. J., Schaffner, S. F., Gabriel, S. B., Platko, J. V., Patterson, N. J., McDonald, G. J., et al. (2002) · Nature · doi:10.1038/nature01140 · Cited by 2,106
A comprehensive review of genetic association studies
Hirschhorn, J. N., Lohmueller, K., Byrne, E., & Hirschhorn, K. (2002) · Genetics in Medicine · doi:10.1097/00125817-200203000-00002 · Cited by 1,674
Skol, A. D., Scott, L. J., Abecasis, G. R., & Boehnke, M. (2006) · Nature Genetics · doi:10.1038/ng1706 · Cited by 1,286
The effects of human population structure on large genetic association studies
Marchini, J., Cardon, L. R., Phillips, M. S., & Donnelly, P. (2004) · Nature Genetics · doi:10.1038/ng1337 · Cited by 869
Global Patterns of Linkage Disequilibrium at the CD4 Locus and Modern Human Origins
Tishkoff, S. A., Dietzsch, E., Speed, W., Pakstis, A. J., Kidd, J. R., Cheung, K., Bonné-Tamir, B., Santachiara-Benerecetti, A. S., Moral, P., Krings, M., et al. (1996) · Science · doi:10.1126/science.271.5254.1380 · Cited by 587
Understanding the multiple functions of Nramp1
Blackwell, J. M., Searle, S., Goswami, T., & Miller, E. N. (2000) · Microbes and Infection · doi:10.1016/s1286-4579(00)00295-1 · Cited by 136
Self-citation
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Yolken, R. H., & Torrey, E. F. (2008) · Molecular Psychiatry · doi:10.1038/mp.2008.5 · Cited by 329
Genetic susceptibility to periodontitis
Laine, M. L., Crielaard, W., & Loos, B. G. (2012) · Periodontology 2000 · doi:10.1111/j.1600-0757.2011.00415.x · Cited by 271
Li, X., Yang, Y., Zhou, F., Zhang, Y., Lu, H., Jin, Q., & Gao, L. (2011) · PLoS ONE · doi:10.1371/journal.pone.0015831 · Cited by 126
Role of immunogenetics in the outcome of HCMV infection: implications for ageing
Aiello, A., Accardi, G., Candore, G., Caruso, C., Colomba, C., Di Bona, D., Duro, G., Gambino, C. M., Ligotti, M. E., & Pandey, J. P. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20030685 · Cited by 38
Metadata
- Authors
- Burgner, D., Jamieson, S. E., & Blackwell, J. M.
- Venue
- The Lancet Infectious Diseases
- Publisher
- Elsevier BV
- Published
- 2006-10
- Volume
- 6
- Issue
- 10
- Pages
- 653-663
- ISSN
- 1473-3099 (ISSN-L)
- OpenAlex
- W2142073962
- Cited by
- 226
- References
- 9
- FWCI
- 6.01
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Burgner, D., Jamieson, S. E., & Blackwell, J. M. (2006). Genetic susceptibility to infectious diseases: big is beautiful, but will bigger be even better? The Lancet Infectious Diseases. https://doi.org/10.1016/s1473-3099(06)70601-6
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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