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Cited by 745

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Tuberculosis-associated immune reconstitution inflammatory syndrome: case definitions for use in resource-limited settings

Open access
Meintjes, Graeme, Lawn, Stephen D, Scano, Fabio, Maartens, Gary, French, Martyn A, Worodria, William, Elliott, Julian H, Murdoch, David, Wilkinson, Robert J, Seyler, Catherine, John, Laurence, van der Loeff, Maarten Schim, Reiss, Peter, Lynen, Lut, Janoff, Edward N, Gilks, Charles, Colebunders, Robert·2008·The Lancet Infectious Diseases

Abstract

The immune reconstitution inflammatory syndrome (IRIS) has emerged as an important early complication of antiretroviral therapy (ART) in resource-limited settings, especially in patients with tuberculosis. However, there are no consensus case definitions for IRIS or tuberculosis-associated IRIS. Moreover, previously proposed case definitions are not readily applicable in settings where laboratory resources are limited. As a result, existing studies on tuberculosis-associated IRIS have used a variety of non-standardised general case definitions. To rectify this problem, around 100 researchers, including microbiologists, immunologists, clinicians, epidemiologists, clinical trialists, and public-health specialists from 16 countries met in Kampala, Uganda, in November, 2006. At this meeting, consensus case definitions for paradoxical tuberculosis-associated IRIS, ART-associated tuberculosis, and unmasking tuberculosis-associated IRIS were derived, which can be used in high-income and resource-limited settings. It is envisaged that these definitions could be used by clinicians and researchers in a variety of settings to promote standardisation and comparability of data.

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Crossref · 10.1016/s1473-3099(08)70184-1

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Metadata

Authors
Meintjes, G., Lawn, S. D., Scano, F., Maartens, G., French, M. A., Worodria, W., Elliott, J. H., Murdoch, D., Wilkinson, R. J., Seyler, C., John, L., van der Loeff, M. S., Reiss, P., Lynen, L., Janoff, E. N., Gilks, C., & Colebunders, R.
Venue
The Lancet Infectious Diseases
Publisher
Elsevier BV
Published
2008-08
Volume
8
Issue
8
Pages
516-523
ISSN
1473-3099 (ISSN-L)
OpenAlex
W2120074558
Cited by
745
References
2
FWCI
54.95
Type
journal article
Language
en
Open access
green

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