The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Clinical epidemiology of the global expansion of Klebsiella pneumoniae carbapenemases
Open accessAbstract
Klebsiella pneumoniae carbapenemases (KPCs) were originally identified in the USA in 1996. Since then, these versatile β-lactamases have spread internationally among Gram-negative bacteria, especially K pneumoniae, although their precise epidemiology is diverse across countries and regions. The mortality described among patients infected with organisms positive for KPC is high, perhaps as a result of the limited antibiotic options remaining (often colistin, tigecycline, or aminoglycosides). Triple drug combinations using colistin, tigecycline, and imipenem have recently been associated with improved survival among patients with bacteraemia. In this Review, we summarise the epidemiology of KPCs across continents, and discuss issues around detection, present antibiotic options and those in development, treatment outcome and mortality, and infection control. In view of the limitations of present treatments and the paucity of new drugs in the pipeline, infection control must be our primary defence for now.
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Yigit, H., Queenan, A. M., Anderson, G. J., Domenech-Sanchez, A., Biddle, J. W., Steward, C. D., Alberti, S., Bush, K., & Tenover, F. C. (2001) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.45.4.1151-1161.2001 · Cited by 1,639
Snitkin, E. S., Zelazny, A. M., Thomas, P. J., Stock, F., Program, N. C. S., Henderson, D. K., Palmore, T. N., & Segre, J. A. (2012) · Science Translational Medicine · doi:10.1126/scitranslmed.3004129 · Cited by 863
Cited by
Portsmouth, S., van Veenhuyzen, D., Echols, R., Machida, M., Ferreira, J. C. A., Ariyasu, M., Tenke, P., & Nagata, T. D. (2018) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(18)30554-1 · Cited by 420
WSES/GAIS/SIS-E/WSIS/AAST global clinical pathways for patients with intra-abdominal infections
Sartelli, M., Coccolini, F., Kluger, Y., Agastra, E., Abu-Zidan, F. M., Abbas, A. E. S., Ansaloni, L., Adesunkanmi, A. K., Atanasov, B., Augustin, G., et al. (2021) · World Journal of Emergency Surgery · doi:10.1186/s13017-021-00387-8 · Cited by 207
Antimicrobial-associated harm in critical care: a narrative review
Arulkumaran, N., Routledge, M., Schlebusch, S., Lipman, J., & Conway Morris, A. (2020) · Intensive Care Medicine · doi:10.1007/s00134-020-05929-3 · Cited by 175
Thabit, A. K., Crandon, J. L., & Nicolau, D. P. (2015) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656566.2015.993381 · Cited by 160
Klebba, P. E., Newton, S. M. C., Six, D. A., Kumar, A., Yang, T., Nairn, B. L., Munger, C., & Chakravorty, S. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.0c01005 · Cited by 150
Metadata
- Authors
- Munoz-Price, L. S., Poirel, L., Bonomo, R. A., Schwaber, M. J., Daikos, G. L., Cormican, M., Cornaglia, G., Garau, J., Gniadkowski, M., Hayden, M. K., Kumarasamy, K., Livermore, D. M., Maya, J. J., Nordmann, P., Patel, J. B., Paterson, D. L., Pitout, J., Villegas, M. V., Wang, H., Woodford, N., & Quinn, J. P.
- Venue
- The Lancet Infectious Diseases
- Publisher
- Elsevier BV
- Published
- 2013-09
- Volume
- 13
- Issue
- 9
- Pages
- 785-796
- ISSN
- 1473-3099 (ISSN-L)
- OpenAlex
- W2145111808
- Cited by
- 1,627
- References
- 2
- FWCI
- 54.09
- Type
- journal article
- Language
- en
- Open access
- green
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- Munoz-Price, L. S., Poirel, L., Bonomo, R. A., Schwaber, M. J., Daikos, G. L., Cormican, M., Cornaglia, G., Garau, J., Gniadkowski, M., Hayden, M. K., Kumarasamy, K., Livermore, D. M., Maya, J. J., Nordmann, P., Patel, J. B., Paterson, D. L., Pitout, J., Villegas, M. V., Wang, H., . . . Quinn, J. P. (2013). Clinical epidemiology of the global expansion of Klebsiella pneumoniae carbapenemases. The Lancet Infectious Diseases. https://doi.org/10.1016/s1473-3099(13)70190-7
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
