Cited by 486Parkinson's Disease Mechanisms and TreatmentsDementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

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Advances in progressive supranuclear palsy: new diagnostic criteria, biomarkers, and therapeutic approaches

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Boxer, Adam L, Yu, Jin-Tai, Golbe, Lawrence I, Litvan, Irene, Lang, Anthony E, Höglinger, Günter U·2017·The Lancet Neurology

DOI 10.1016/s1474-4422(17)30157-6PMC PMC5802400

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Abstract

Progressive supranuclear palsy (PSP), previously believed to be a common cause of atypical parkinsonism, is now recognised as a range of motor and behavioural syndromes that are associated with a characteristic 4-repeat tau neuropathology. New research criteria that recognise early presentations of PSP and operationalise diagnosis of the full spectrum of clinical phenotypes have been reported. The Movement Disorders Society PSP diagnostic criteria include syndromes with few or mild symptoms that are suggestive of underlying PSP pathology and could provide an opportunity for earlier therapeutic interventions in the future. These criteria also include definitions for variant PSP syndromes with different patterns of movement, language, or behavioural features than have been conclusively associated with PSP pathology. Data from new diagnostic biomarkers can be combined with the clinical features of disease to increase the specificity of the new criteria for underlying PSP pathology. Because PSP is associated with tau protein abnormalities, there is growing interest in clinical trials of new tau-directed therapies. These therapies are hypothesised to have disease-modifying effects by reducing the concentration of toxic forms of tau in the brain or by compensating for loss of tau function. Since tau pathology is also central to Alzheimer's disease and chronic traumatic encephalopathy, a successful tau therapeutic for PSP might inform treatment of other neurodegenerative diseases.

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Gnörich, J. S., Kusche‐Palenga, J., Kling, A., Dehsarvi, A., Bronte, A., Frontzkowski, L. K., Zatcepin, A., Zaganjori, M., Schöberl, F., Roemer, S. N., et al. (2026) · Molecular Neurodegeneration · doi:10.1186/s13024-026-00997-3
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Authors: Boxer, A. L., Yu, J.-T., Golbe, L. I., Litvan, I., Lang, A. E., & Höglinger, G. U.
Affiliations: University of California, San Francisco (US)
Qingdao University (CN)
Rutgers, The State University of New Jersey (US)
University of California San Diego (US)
University of Toronto (CA)
German Center for Neurodegenerative Diseases (DE)
Corresponding author: Boxer, Adam L
ORCID: Boxer, Adam L
Yu, Jin-Tai
Golbe, Lawrence I
Litvan, Irene
Lang, Anthony E
Höglinger, Günter U
Venue: The Lancet Neurology
Publisher: Elsevier BV
Published: 2017-07
Volume: 16
Issue: 7
Pages: 552-563
ISSN: 1474-4422 (ISSN-L)
DOI: 10.1016/s1474-4422(17)30157-6
PMC: PMC5802400
OpenAlex: W2625168757
Cited by: 485
References: 105
Citations by year: 2026: 45 · 2025: 52 · 2024: 59 · 2023: 42 · 2022: 57 · 2021: 56 · 2020: 62 · 2019: 61 · 2018: 43 · 2017: 7
FWCI: 6.28
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: The Lancet Neurology (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
eScholarship (California Digital Library) (submittedVersion)
mediaTUM – the media and publications repository of the Technical University Munich (Technical University Munich) (submittedVersion)
DZNE Pub (submittedVersion)
Funders: Deutsche Forschungsgemeinschaft (HO2402/6‐2)
National Institutes of Health
National Institute on Aging (P50AG005131, U01AG045390, R01AG038791, P01AG019724)
National Heart, Lung, and Blood Institute (T35HL007491)
National Institute of Neurological Disorders and Stroke (U01NS086659, U54NS092089)
Topics: Health Sciences › Medicine › Clinical Neurology › Parkinson's Disease Mechanisms and Treatments
Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Alzheimer's disease research and treatments
Keywords: progressive supranuclear palsy, diagnostic criteria, tau pathology, 4-repeat tau, biomarkers, atypical parkinsonism, disease-modifying therapy, neurodegenerative diseases, Alzheimer's disease, chronic traumatic encephalopathy
MeSH terms: Humans, Supranuclear Palsy, Progressive, Biomarkers

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Advances in progressive supranuclear palsy: new diagnostic criteria, biomarkers, and therapeutic approaches

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