Cited by 105Climate Change and Health ImpactsHealth, Environment, Cognitive AgingAir Quality and Health Impacts

Climate change and disorders of the nervous system

Open access
Sisodiya, Sanjay M, Gulcebi, Medine I, Fortunato, Francesco, Mills, James D, Haynes, Ethan, Bramon, Elvira, Chadwick, Paul, Ciccarelli, Olga +16 more·2024·The Lancet Neurology

Abstract

Anthropogenic climate change is affecting people's health, including those with neurological and psychiatric diseases. Currently, making inferences about the effect of climate change on neurological and psychiatric diseases is challenging because of an overall sparsity of data, differing study methods, paucity of detail regarding disease subtypes, little consideration of the effect of individual and population genetics, and widely differing geographical locations with the potential for regional influences. However, evidence suggests that the incidence, prevalence, and severity of many nervous system conditions (eg, stroke, neurological infections, and some mental health disorders) can be affected by climate change. The data show broad and complex adverse effects, especially of temperature extremes to which people are unaccustomed and wide diurnal temperature fluctuations. Protective measures might be possible through local forecasting. Few studies project the future effects of climate change on brain health, hindering policy developments. Robust studies on the threats from changing climate for people who have, or are at risk of developing, disorders of the nervous system are urgently needed.

Integrity signals

Registry

Crossref · 10.1016/s1474-4422(24)00087-5

Cites

135 of 135 references verified0 citation errors · 0 not checkable

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  • Heatwaves increase the risk of adverse pregnancy and birth outcomes and exacerbate adverse neurological conditions.

    “They also increase the risk of adverse pregnancy and birth outcomes and exacerbate adverse neurological conditions”
  • Because of degenerate systems and the lack of stationarity in our world, it is most difficult to achieve standards of reliability in exactly those circumstances in which it is most critical for public policy or decision-making.

    “Unfortunately, because of degenerate systems and the lack of stationarity in our world, it is most difficult to achieve standards of reliability in exactly those circumstances in which it is most critical for public policy or decision-making [72,73].”

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Authors
Sisodiya, S. M., Gulcebi, M. I., Fortunato, F., Mills, J. D., Haynes, E., Bramon, E., Chadwick, P., Ciccarelli, O., David, A. S., De Meyer, K., Fox, N. C., Davan Wetton, J., Koltzenburg, M., Kullmann, D. M., Kurian, M. A., Manji, H., Maslin, M. A., Matharu, M., Montgomery, H., Romanello, M., Werring, D. J., Zhang, L., Friston, K. J., & Hanna, M. G.
Affiliations
  • UCL Queen Square Institute of Neurology (GB)
  • University College London (GB)
  • UCL Biomedical Research Centre (GB)
  • UK Dementia Research Institute (GB)
  • National Hospital for Neurology and Neurosurgery (GB)
  • University of Copenhagen (DK)
  • Wellcome Centre for Human Neuroimaging (GB)
Corresponding author
Sisodiya, Sanjay M
Venue
The Lancet Neurology
Publisher
Elsevier BV
Published
2024-06
Volume
23
Issue
6
Pages
636-648
ISSN
1474-4422 (ISSN-L)
OpenAlex
W4396915267
Cited by
105
References
136
Citations by year
2026: 40 · 2025: 51 · 2024: 14
FWCI
4.51
Type
journal article
Language
en
Open access
Locations
  • The Lancet Neurology (publishedVersion)
  • PubMed (publishedVersion)
  • UCL Discovery (University College London) (submittedVersion)
Funders
  • Wellcome Trust
  • MRC
  • Epilepsy Society
Topics
  • Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Climate Change and Health Impacts
  • Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Health, Environment, Cognitive Aging
  • Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Air Quality and Health Impacts
Keywords
climate change, neurological disorders, mental illness, temperature extremes, diurnal temperature range, stroke, neurological infections, mental health, climate change adaptation
MeSH terms
Humans, Nervous System Diseases, Climate Change

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