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Cited by 379Alcohol Consumption and Health EffectsGastrointestinal motility and disordersGut microbiota and health

The DOI matches its Crossref record; 82 of the 83 references it cites were found in a registry or an index.

Effect of alcohol consumption on the gut.

Bode, Christiane, Christian Bode, J·2003·Best Practice & Research Clinical Gastroenterology
DOI 10.1016/s1521-6918(03)00034-9
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Abstract

Consumption of large quantities of alcoholic beverages leads to disturbances in the intestinal absorption of nutrients including several vitamins. The inhibition of the absorption of sodium and water caused by alcohol contributes to the tendency in alcoholics to develop diarrhoea. Excessive alcohol consumption (even a single episode) can result in duodenal erosions and bleeding and mucosal injury in the upper jejunum. An increased prevalence for bacterial overgrowth in the small intestine may contribute to functional and/or morphological abnormalities of this part of the gut and also to non-specific abdominal complaints in alcoholics. The mucosal damage caused by alcohol increases the permeability of the gut to macromolecules. This facilitates the translocation of endotoxin and other bacterial toxins from the gut lumen to the portal blood, thereby increasing the liver's exposure to these toxins and, consequently, the risk of liver injury. The results of recent experimental studies support the assumption that alcohol significantly modulates the mucosal immune system of the gut.

Overview

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Crossref · 10.1016/s1521-6918(03)00034-9

Cites

82 of 82 references verified0 citation errors · 0 not checkable

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Citations

Cites

Show all 83 references

Research works printed but not linked: 1

  1. Beck, 1988, Evidence for the involment of 5-lipoxygenase products in the ethanol-induced intestinal plasma protein loss, American Journal of Physiology, 254, 483

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Metadata

Authors
Bode, C., & Christian Bode, J.
Affiliations
University of Hohenheim (DE)
Corresponding author
Bode, Christiane
Venue
Best Practice & Research Clinical Gastroenterology
Publisher
Elsevier BV
Published
2003-08
Volume
17
Issue
4
Pages
575-592
ISSN
1521-6918 (ISSN-L)
DOI
10.1016/s1521-6918(03)00034-9
OpenAlex
W2144658154
Cited by
379
References
83
Citations by year
2026: 7 · 2025: 20 · 2024: 16 · 2023: 20 · 2022: 25 · 2021: 27 · 2020: 16 · 2019: 24 · 2018: 13 · 2017: 17 · 2016: 21 · 2015: 20 · 2014: 20 · 2013: 14 · 2012: 18
FWCI
1.56
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Best Practice & Research Clinical Gastroenterology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
  • Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
Keywords
alcohol consumption, intestine, intestinal absorption, vitamin absorption, diarrhea, duodenal erosions, mucosal injury, bacterial overgrowth, small intestine, intestinal permeability, endotoxin translocation, liver injury, mucosal immune system, alcoholism
MeSH terms
Alcohol Drinking, Ethanol, Alcoholic Beverages, Alcoholism, Animals, Gastrointestinal Motility, Humans, Intestinal Absorption, Intestinal Mucosa, Permeability, Malnutrition

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