The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
LHY and CCA1 Are Partially Redundant Genes Required to Maintain Circadian Rhythms in Arabidopsis
Open accessAbstract
Several genes are known to regulate circadian rhythms in Arabidopsis, but the identity of the central oscillator has not been established. LHY and CCA1 are related MYB-like transcription factors proposed to be closely involved. Here we demonstrate that, as shown previously for CCA1, inactivation of LHY shortens the period of circadian rhythms in gene expression and leaf movements. By constructing lhy cca1-1 double mutants, we show that LHY and CCA1 are partially redundant and essential for the maintenance of circadian rhythms in constant light. Under light/dark cycles the lhy cca1-1 plants show dramatically earlier phases of expression of GI and TOC1, genes associated with the generation of circadian rhythms and the promotion of LHY and CCA1 expression. We conclude that LHY and CCA1 appear to be negative regulatory elements required for central oscillator function.
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Citations
Cites
Analysis of the genome sequence of the flowering plant Arabidopsis thaliana
Initiative, T. A. G. (2000) · Nature · doi:10.1038/35048692 · Cited by 9,301
Molecular Bases for Circadian Clocks
Dunlap, J. C. (1999) · Cell · doi:10.1016/s0092-8674(00)80566-8 · Cited by 2,900
Nonredundant roles of the mPer1 and mPer2 genes in the mammalian circadian clock.
Zheng, B., Albrecht, U., Kaasik, K., Sage, M., Lu, W., Vaishnav, S., Li, Q., Sun, Z. S., Eichele, G., Bradley, A., et al. (2001) · Cell · doi:10.1016/s0092-8674(01)00380-4 · Cited by 900
Cited by
Yanhui, C., Xiaoyuan, Y., Kun, H., Meihua, L., Jigang, L., Zhaofeng, G., Zhiqiang, L., Yunfei, Z., Xiaoxiao, W., Xiaoming, Q., et al. (2006) · Plant Molecular Biology · doi:10.1007/s11103-005-2910-y · Cited by 992
The clock gene circuit in Arabidopsis includes a repressilator with additional feedback loops
Pokhilko, A., Fernández, A. P., Edwards, K. D., Southern, M. M., Halliday, K. J., & Millar, A. J. (2012) · Molecular Systems Biology · doi:10.1038/msb.2012.6 · Cited by 409
Living by the calendar: how plants know when to flower
Yanovsky, M. J., & Kay, S. A. (2003) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1077 · Cited by 317
A Genomic Analysis of the Shade Avoidance Response in Arabidopsis
Devlin, P. F., Yanovsky, M. J., & Kay, S. A. (2003) · Plant Physiology · doi:10.1104/pp.103.034397 · Cited by 275
BRANCHED1 Promotes Axillary Bud Dormancy in Response to Shade in Arabidopsis
González-Grandío, E., Poza-Carrión, C., Sorzano, C. O. S., & Cubas, P. (2013) · The Plant Cell · doi:10.1105/tpc.112.108480 · Cited by 272
Metadata
- Authors
- Mizoguchi, T., Wheatley, K., Hanzawa, Y., Wright, L., Mizoguchi, M., Song, H.-R., Carré, I. A., & Coupland, G.
- Venue
- Developmental Cell
- Publisher
- Elsevier BV
- Published
- 2002-05
- Volume
- 2
- Issue
- 5
- Pages
- 629-641
- ISSN
- 1534-5807 (ISSN-L)
- OpenAlex
- W1969482758
- Cited by
- 638
- References
- 3
- FWCI
- 33.94
- Type
- journal article
- Language
- en
- Open access
- bronze
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- The paper
- Mizoguchi, T., Wheatley, K., Hanzawa, Y., Wright, L., Mizoguchi, M., Song, H.-R., Carré, I. A., & Coupland, G. (2002). LHY and CCA1 Are Partially Redundant Genes Required to Maintain Circadian Rhythms in Arabidopsis. Developmental Cell. https://doi.org/10.1016/s1534-5807(02)00170-3
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