P1/HC-Pro, a Viral Suppressor of RNA Silencing, Interferes with Arabidopsis Development and miRNA Function
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In Arabidopsis, suppression of RNA silencing, which shares a common pathway with miRNA processing, results in developmental defects.
“In Arabidopsis, suppression of RNA silencing, which shares a common pathway with miRNA processing, results in developmental defects (Kasschau et al. 2003).”
From A microRNA array reveals extensive regulation of microRNAs during brain development (2003) · cites this paper as Kasschau et al. 2003
The Results and Discussion report that Arabidopsis plants expressing the RNA-silencing suppressor P1/HC-Pro developed severe abnormalities. They also show interference with miRNA-guided activity, but locate it downstream of miRNA processing; the claim’s description of a common pathway with miRNA processing is therefore more specific than the paper establishes. (LLM, conf=0.82)
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Wightman, B., Ha, I., & Ruvkun, G. (1993) · Cell · doi:10.1016/0092-8674(93)90530-4 · Cited by 4,292 · see citing works
Genes involved in organ separation in Arabidopsis: an analysis of the cup-shaped cotyledon mutant.
Aida, M., Ishida, T., Fukaki, H., Fujisawa, H., & Tasaka, M. (1997) · The Plant Cell · doi:10.1105/tpc.9.6.841 · Cited by 1,486 · see citing works
Di Laurenzio, L., Wysocka-Diller, J., Malamy, J. E., Pysh, L., Helariutta, Y., Freshour, G., Hahn, M. G., Feldmann, K. A., & Benfey, P. N. (1996) · Cell · doi:10.1016/s0092-8674(00)80115-4 · Cited by 1,124 · see citing works
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Research works printed but not linked: 51
- [2]2. Ambros, V. microRNAstiny regulators with great potential Cell. 2001; 107:823-826 Full Text Full Text (PDF) Scopus (1521) PubMed Google Scholar
- [3]3. Anandalakshmi, R. ∙ Pruss, G.J. ∙ Ge, X. ... A viral suppressor of gene silencing in plants Proc. Natl. Acad. Sci. USA. 1998; 95:13079-13084 Crossref Scopus (728) PubMed Google Scholar
- [4]4. Bernstein, E. ∙ Caudy, A.A. ∙ Hammond, S.M. ... Role for a bidentate ribonuclease in the initiation step of RNA interference Nature. 2001; 409:363-366 Crossref Scopus (3958) PubMed Google Scholar
- [5]5. Brigneti, G. ∙ Voinnet, O. ∙ Wan-Xiang, L. ... Viral pathogenicity determinants are suppressors of transgene silencing EMBO J. 1998; 17:6739-6746 Crossref Scopus (936) PubMed Google Scholar
- [6]6. Cardon, G. ∙ Hohmann, S. ∙ Klein, J. ... Molecular characterization of the Arabidopsis SBP-box genes Gene. 1999; 237:91-104 Crossref Scopus (335) PubMed Google Scholar
- [7]7. Carrington, J.C. ∙ Freed, D.D. ∙ Oh, C.-S. Expression of potyviral polyproteins in transgenic plants reveals three proteolytic activities required for complete processing EMBO J. 1990; 9:1347-1353 PubMed Google Scholar
- [8]8. Clough, S.J. ∙ Bent, A.F. Floral dipa simplified method for Agrobacterium-mediated transformation of Arabidopsis thaliana Plant J. 1998; 16:735-743 Crossref PubMed Google Scholar
- [9]9. Dalmay, T. ∙ Hamilton, A. ∙ Rudd, S. ... An RNA-dependent RNA polymerase gene in Arabidopsis is required for posttranscriptional gene silencing mediated by a transgene but not by a virus Cell. 2000; 101:543-553 Full Text Full Text (PDF) Scopus (879) PubMed Google Scholar
- [11]11. Elbashir, S.M. ∙ Lendeckel, W. ∙ Tuschl, T. RNA interference is mediated by 21- and 22-nucleotide RNAs Genes Dev. 2001; 15:188-200 Crossref Scopus (2778) PubMed Google Scholar
- [12]12. Feinberg, A.P. ∙ Vogelstein, B. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity Anal. Biochem. 1983; 257:8569-8572 Google Scholar
- [13]13. Golden, T.A. ∙ Schauer, S.E. ∙ Lang, J.D. ... Short integuments1/suspensor1/carpel factory, a Dicer homolog, is a maternal effect gene required for embryo development in Arabidopsis Plant Physiol. 2002; 130:808-822 Crossref Scopus (141) PubMed Google Scholar
- [14]14. Grishok, A. ∙ Pasquinelli, A.E. ∙ Conte, D. ... Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing Cell. 2001; 106:23-34 Full Text Full Text (PDF) Scopus (1578) PubMed Google Scholar
- [15]15. Hamilton, A.J. ∙ Baulcombe, D.C. A species of small antisense RNA in posttranscriptional gene silencing in plants Science. 1999; 286:950-952 Crossref Scopus (2422) PubMed Google Scholar
- [16]16. Hammond, S.M. ∙ Bernstein, E. ∙ Beach, D. ... An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells Nature. 2000; 404:293-296 Crossref Scopus (2491) PubMed Google Scholar
- [17]17. Hannon, G.J. RNA interference Nature. 2002; 418:244-251 Crossref Scopus (3651) PubMed Google Scholar
- [18]18. Helariutta, Y. ∙ Fukaki, H. ∙ Wysocka-Diller, J. ... The SHORT-ROOT gene controls radial patterning of the Arabidopsis root through radial signaling Cell. 2000; 101:555-567 Full Text Full Text (PDF) Scopus (880) PubMed Google Scholar
- [19]19. Hull, R. Matthews' Plant Virology.Academic Press, San Diego, 2001 Google Scholar
- [20]20. Hutvágner, G. ∙ McLachlan, J. ∙ Pasquinelli, A.E. ... A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA Science. 2001; 293:834-838 Crossref Scopus (2258) PubMed Google Scholar
- [21]21. Hutvágner, G. ∙ Zamore, P.D. A microRNA in a multiple-turnover RNAi enzyme complex Science. 2002; 297:2056-2059 Crossref Scopus (1700) PubMed Google Scholar
- [22]22. Jacobsen, S.E. ∙ Running, M.P. ∙ Meyerowitz, E.M. Disruption of an RNA helicase/RNAse III gene in Arabidopsis causes unregulated cell division in floral meristems Development. 1999; 126:5231-5243 PubMed Google Scholar
- [23]23. Johansen, L.K. ∙ Carrington, J.C. Silencing on the spotinduction and suppression of RNA silencing in the Agrobacterium-mediated transient expression system Plant Physiol. 2001; 126:930-938 Crossref Scopus (432) PubMed Google Scholar
- [24]24. Jones, J.D. ∙ Shlumukov, L. ∙ Carland, F. ... Effective vectors for transformation, expression of heterologous genes, and assaying transposon excision in transgenic plants Transgenic Res. 1992; 1:285-297 Crossref Scopus (268) PubMed Google Scholar
- [25]25. Kasschau, K.D. ∙ Carrington, J.C. A counterdefensive strategy of plant virusessuppression of posttranscriptional gene silencing Cell. 1998; 95:461-470 Full Text Full Text (PDF) Scopus (690) PubMed Google Scholar
- [26]26. Kasschau, K.D. ∙ Carrington, J.C. Long-distance movement and replication maintenance functions correlate with silencing suppression activity of potyviral HC-Pro Virology. 2001; 285:71-81 Crossref Scopus (171) PubMed Google Scholar
- [27]27. Ketting, R.F. ∙ Fischer, S.E. ∙ Bernstein, E. ... Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans Genes Dev. 2001; 15:2654-2659 Crossref Scopus (1505) PubMed Google Scholar
- [28]28. Lang, J.D. ∙ Ray, S. ∙ Ray, A. sin1, a mutation affecting female fertility in Arabidopsis, interacts with mod1, its recessive modifier Genetics. 1994; 137:1101-1110 PubMed Google Scholar
- [29]29. Lellis, A.D. ∙ Kasschau, K.D. ∙ Whitham, S.A. ... Loss-of-susceptibility mutants of Arabidopsis thaliana reveal an essential role for eIF(iso)4E during potyvirus infection Curr. Biol. 2002; 12:1046-1051 Full Text Full Text (PDF) Scopus (328) PubMed Google Scholar
- [30]30. Liscum, E. ∙ Reed, J.W. Genetics of AUX/IAA and ARF action in plant growth and development Plant Mol. Biol. 2002; 49:387-400 Crossref Scopus (669) PubMed Google Scholar
- [31]31. Liu, H. ∙ Reavy, B. ∙ Swanson, M. ... Functional replacement of the tobacco rattle virus cysteine-rich protein by pathogenicity proteins from unrelated plant viruses Virology. 2002; 298:232-239 Crossref Scopus (64) PubMed Google Scholar
- [32]32. Llave, C. ∙ Kasschau, K.D. ∙ Rector, M.A. ... Endogenous and silencing-associated small RNAs in plants Plant Cell. 2002; 14:1605-1619 Crossref Scopus (795) PubMed Google Scholar
- [33]33. Llave, C. ∙ Xie, Z. ∙ Kasschau, K.D. ... Cleavage of Scarecrow-like mRNA targets is directed by a class of Arabidopsis miRNA Science. 2002; 297:2053-2056 Crossref Scopus (1360) PubMed Google Scholar
- [34]34. Mallory, A.C. ∙ Reinhart, B.J. ∙ Bartel, D. ... A viral suppressor of RNA silencing differentially regulates the accumulation of short interfering RNAs and micro-RNAs in tobacco Proc. Natl. Acad. Sci. USA. 2002; 99:15228-15233 Crossref Scopus (209) PubMed Google Scholar
- [35]35. Mourrain, P. ∙ Beclin, C. ∙ Elmayan, T. ... Arabidopsis SGS2 and SGS3 genes are required for posttranscriptional gene silencing and natural virus resistance Cell. 2000; 101:533-542 Full Text Full Text (PDF) Scopus (900) PubMed Google Scholar
- [36]36. Olsen, P.H. ∙ Ambros, V. The lin-4 regulatory RNA controls developmental timing in Caenorhabditis elegans by blocking LIN-14 protein synthesis after the initiation of translation Dev. Biol. 1999; 216:671-680 Crossref Scopus (972) PubMed Google Scholar
- [37]37. Park, W. ∙ Li, J. ∙ Song, R. ... CARPEL FACTORY, a Dicer homolog, and HEN1, a novel protein, act in microRNA metabolism in Arabidopsis thaliana Curr. Biol. 2002; 12:1484-1495 Full Text Full Text (PDF) Scopus (1037) PubMed Google Scholar
- [38]38. Pasquinelli, A.E. ∙ Ruvkun, G. Control of developmental timing by microRNAs and their targets Annu. Rev. Cell Dev. Biol. 2002; 18:495-513 Crossref Scopus (293) PubMed Google Scholar
- [39]39. Qiu, W. ∙ Park, J.W. ∙ Scholthof, H.B. Tombusvirus P19-mediated suppression of virus-induced gene silencing is controlled by genetic and dosage features that influence pathogenicity Mol. Plant Microbe Interact. 2002; 15:269-280 Crossref Scopus (146) PubMed Google Scholar
- [40]40. Ray, A. ∙ Lang, J.D. ∙ Golden, T. ... SHORT INTEGUMENTS1 (SIN1), a gene required for ovule development in Arabidopsis, also controls flowering time Development. 1996; 122:2631-2638 PubMed Google Scholar
- [41]41. Ray, S. ∙ Golden, T. ∙ Ray, A. Maternal effects of the short integuments1 mutation on embryo development Dev. Biol. 1996; 180:365-369 Crossref Scopus (89) PubMed Google Scholar
- [42]42. Reichmann, J.L. ∙ Meyerowitz, E.M. The AP2/EREBP family of plant transcription factors Biol. Chem. 1998; 379:633-646 PubMed Google Scholar
- [43]43. Reinhart, B.J. ∙ Weinstein, E.G. ∙ Rhoades, M.W. ... MicroRNAs in plants Genes Dev. 2002; 16:1616-1626 Crossref Scopus (1835) PubMed Google Scholar
- [44]44. Restrepo, M.A. ∙ Freed, D.D. ∙ Carrington, J.C. Nuclear transport of plant potyviral proteins Plant Cell. 1990; 2:987-998 PubMed Google Scholar
- [45]45. Rhoades, M.W. ∙ Reinhart, B.J. ∙ Lim, L.P. ... Prediction of plant microRNA targets Cell. 2002; 110:513-520 Full Text Full Text (PDF) Scopus (1891) PubMed Google Scholar
- [46]46. Robinson-Beers, K. ∙ Pruitt, R.E. ∙ Gasser, C.S. Ovule development in wild-type Arabidopsis and two female sterile mutants Plant Cell. 1992; 4:1237-1250 PubMed Google Scholar
- [47]47. Schauer, S.E. ∙ Jaconsen, S.E. ∙ Meinke, D.W. ... DICER-LIKE1blind men and elephants in arabidopsis development Trends Plant Sci. 2002; 7:487-491 Full Text Full Text (PDF) Scopus (412) PubMed Google Scholar
- [48]48. Schwartz, B.W. ∙ Yeung, E.C. ∙ Meinke, D.W. Disruption of morphogenesis and transformation of the suspensor in abnormal suspensor mutants of Arabidopsis Dev. Biol. 1994; 120:3235-3245 Google Scholar
- [49]49. Silverstone, A.L. ∙ Ciampaglio, C.N. ∙ Sun, T. The Arabidopsis RGA gene encodes a transcriptional regulator repressing the gibberellin signal transduction pathway Plant Cell. 1998; 10:155-169 PubMed Google Scholar
- [50]50. Tang, G. ∙ Reinhart, B.J. ∙ Bartel, D.P. ... A biochemical framework for RNA silencing in plants Genes Dev. 2003; 17:49-63 Crossref Scopus (827) PubMed Google Scholar
- [51]51. Vance, V. ∙ Vaucheret, H. RNA silencing in plants—defense and counterdefense Science. 2001; 292:2277-2280 Crossref Scopus (526) PubMed Google Scholar
- [52]52. Voinnet, O. ∙ Lederer, C. ∙ Baulcombe, D.C. A viral movement protein prevents spread of the gene silencing signal in Nicotiana benthamiana Cell. 2000; 103:157-167 Full Text Full Text (PDF) Scopus (555) PubMed Google Scholar
- [53]53. Voinnet, O. ∙ Pinto, V.M. ∙ Baulcombe, D.C. Suppression of gene silencinga general strategy used by diverse DNA and RNA viruses of plants Proc. Natl. Acad. Sci. USA. 1999; 96:14147-14152 Crossref Scopus (865) PubMed Google Scholar
Cited by
Sorted by citations
Specific effects of microRNAs on the plant transcriptome
Schwab, R., Palatnik, J. F., Riester, M., Schommer, C., Schmid, M., & Weigel, D. (2005) · Developmental Cell · doi:10.1016/j.devcel.2005.01.018 · Cited by 1,467 · see citing works
A microRNA array reveals extensive regulation of microRNAs during brain development
KRICHEVSKY, A. M., KING, K. S., DONAHUE, C. P., KHRAPKO, K., & KOSIK, K. S. (2003) · RNA · doi:10.1261/rna.5980303 · Cited by 1,040 · see citing works
- Authors
- Kasschau, K. D., Xie, Z., Allen, E., Llave, C., Chapman, E. J., Krizan, K. A., & Carrington, J. C.
- Venue
- Developmental Cell
- Publisher
- Elsevier BV
- Published
- 2003-02
- Volume
- 4
- Issue
- 2
- Pages
- 205-217
- ISSN
- 1534-5807
- Cited by
- 817
- References
- 3
- Language
- en
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