Etiology of Liver Cirrhosis in Mexico
Open accessAbstract
BACKGROUND: In the last decades it has been suggested that the main cause of liver cirrhosis in Mexico is alcohol. Currently in Western countries hepatitis C virus stage liver disease and liver transplantation. In Mexico, we have no data relative to the etiology of liver cirrhosis. The aim of this study was to investigate the main causes of liver cirrhosis in Mexico. METHODS: Eight hospitals located in different areas of the country were invited to participate in this study. Those hospitals provide health care to different social classes of the country. The inclusion criteria were the presence of either an histological or a clinical and biochemical diagnosis of liver cirrhosis. RESULTS: A total 1,486 cases were included in this study. The etiology of liver cirrhosis was alcohol in 587 (39.5%), HCV 544 (36.6%), cryptogenic 154 (10.4%), PBC 84 (5.7%), HBV 75 (5.0%) and other 42 (2.8%). There was no statistical difference between alcohol and HCV. CONCLUSIONS: We conclude that the main causes of liver cirrhosis in Mexico are alcohol and HCV.
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Heavy alcohol consumption is likely to be the main cause of liver cirrhosis in most parts of Latin America.
“Heavy alcohol consumption is likely to be the main cause of liver cirrhosis in most parts of Latin America [20,70–72] (Figure 2, Additional file 6: Table S6).”
From Liver cirrhosis mortality in 187 countries between 1980 and 2010: a systematic analysis (2014) · cites this paper as [72]
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- Authors
- Méndez-Sánchez, N., Aguilar-Ramírez, J. R., Reyes, A., Dehesa, M., Juárez, A., Castañeda, B., Sánchez-Avila, F., Poo, J. L., Guevara González, L., Lizardi, J., Valdovinos, M. A., Uribe, M., Contreras, A. M., Tirado, P., Aguirre, J., Rivera-Benítez, C., Santiago-Santiago, R., Bosques-Padilla, F., Muñoz, L., Guerrero, A., Ramos, M., Rodríguez-Hernández, H., & Jacobo-Karam, J.
- Affiliations
- Centro Medico Nacional Siglo XXI (MX)
- Hospital General de México (MX)
- Venue
- Annals of Hepatology
- Publisher
- Elsevier BV
- Published
- 2004-01
- Volume
- 3
- Issue
- 1
- Pages
- 30-33
- ISSN
- 1665-2681 (ISSN-L)
- OpenAlex
- W2140177922
- Cited by
- 106
- References
- 30
- Citations by year
- 2026: 3 · 2025: 2 · 2023: 4 · 2022: 5 · 2021: 6 · 2020: 4 · 2019: 4 · 2018: 4 · 2017: 4 · 2016: 4 · 2015: 6 · 2014: 4 · 2013: 3 · 2012: 1
- FWCI
- 5.38
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Annals of Hepatology (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Health Sciences › Medicine › Hepatology › Liver Disease and Transplantation
- Health Sciences › Medicine › Hepatology › Liver Diseases and Immunity
- Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
- Keywords
- liver cirrhosis, etiology, alcoholic liver disease, hepatitis C virus, cryptogenic cirrhosis, primary biliary cirrhosis, hepatitis B virus, Mexico
- MeSH terms
- Adolescent, Adult, Aged, Aged, 80 and over, Alcoholism, Child, Cross-Sectional Studies, Female, Hepatitis B, Hepatitis C, Humans, Liver Cirrhosis, Male, Mexico, Middle Aged, Prospective Studies, Age Distribution
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