CoChat
Sign Up
Cited by 101Infective Endocarditis Diagnosis and ManagementStreptococcal Infections and TreatmentsCardiac Valve Diseases and Treatments

Staphylococcus lugdunensis Infective Endocarditis: A Literature Review and Analysis of Risk Factors

Open access
Liu, Po-Yen, Huang, Yung-Feng, Tang, Chia-Wan, Chen, Ying-Yao, Hsieh, Kai-Sheng, Ger, Luo-Ping, Chen, Yao-Shen, Liu, Yung-Ching·2010·Journal of Microbiology, Immunology and Infection
DOI 10.1016/s1684-1182(10)60074-6
Open this paper in CoChat — free accountOpen PDF

Abstract

Background/purpose Infective endocarditis caused by Staphylococcus lugdunensis is a rare disease. Since its first description in 1988, there have only been a few reports of this disease and the causative organism. These publications were primarily case reports and brief case series. We conducted a literature review to identify the nature of the disease and its risk factors.Methods We retrospectively reviewed the cases reported between 1988 and 2008 by searching the relevant literature using the keywords "endocarditis" and "Staphylococcus lugdunensis" in the Medline database. All cases included met the definition of the modified Duke criteria.Results For the period 1988-2008, 67 cases from 27 articles were reviewed. The mean age of individuals was 53.9 years. Left-sided valvular endocarditis represented 52 (82.5%) of cases and native-valve endocarditis was evident in 48 (78.7%) of cases. A large proportion (82%) of 50 S. lugdunensis strains were susceptible to penicillin. Valve replacement operations were performed in 42 (66.7%) patients and the mortality rate was 38.8%. Univariate analysis showed a higher mortality rate in patients aged more than 50 years, those treated before 1995, those treated with antibiotics alone, and those with growth not detected by echocardiography. Medical treatment alone was the independent risk factor for mortality by multivariate analysis.Conclusion S. lugdunensis endocarditis led to substantial morbidity and mortality. Detailed microbiological identification, echocardiography evaluation, and valve replacement may improve the clinical outcome of individuals with S. lugdunensis endocarditis.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1016/s1684-1182(10)60074-6

Cites

45 of 45 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

Research works printed but not linked: 2

  1. [11]11. Shuttleworth R, Colby WD. Staphylococcus lugdunensis endocardi- tis. J Clin Microbiol 1992;30:1948-52.
  2. [18]18. Farrag N, Lee P, Gunney R, Viagappan GM. Staphylococcus lugdunensis endocarditis. Postgrad Med J 2001;77:259-60.

Cited by

Sorted by citations

Related

Authors
Liu, P.-Y., Huang, Y.-F., Tang, C.-W., Chen, Y.-Y., Hsieh, K.-S., Ger, L.-P., Chen, Y.-S., & Liu, Y.-C.
Affiliations
  • Kaohsiung Veterans General Hospital (TW)
  • Taipei Medical University-Shuang Ho Hospital (TW)
Corresponding author
Huang, Yung-Feng
ORCID
Venue
Journal of Microbiology, Immunology and Infection
Publisher
Elsevier BV
Published
2010-12
Volume
43
Issue
6
Pages
478-484
ISSN
1684-1182 (ISSN-L)
DOI
10.1016/s1684-1182(10)60074-6
OpenAlex
W2053855237
Semantic Scholar
d814d1189e3b99b4a9138daf40a6f0a085ea0339
Cited by
101
References
45
Citations by year
2026: 3 · 2025: 5 · 2024: 7 · 2023: 8 · 2022: 12 · 2021: 9 · 2020: 6 · 2019: 6 · 2018: 7 · 2017: 3 · 2016: 7 · 2015: 4 · 2014: 9 · 2013: 4 · 2012: 3
FWCI
3.46
Type
journal article
Language
en
Open access
Licence
Locations
  • Journal of Microbiology Immunology and Infection (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Epidemiology › Infective Endocarditis Diagnosis and Management
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Streptococcal Infections and Treatments
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Valve Diseases and Treatments
Keywords
Staphylococcus lugdunensis, infective endocarditis, risk factors, mortality, native valve endocarditis, penicillin susceptibility, valve replacement, echocardiographic detection, antibiotic therapy, modified Duke criteria
MeSH terms
Adolescent, Adult, Aged, Aged, 80 and over, Anti-Bacterial Agents, Child, Echocardiography, Endocarditis, Bacterial, Female, Humans, Male, Middle Aged, Prognosis, Risk Factors, Staphylococcal Infections, Young Adult, Staphylococcus lugdunensis

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review