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Particle sizes of infectious aerosols: implications for infection control
Open accessAbstract
The global pandemic of COVID-19 has been associated with infections and deaths among health-care workers. This Viewpoint of infectious aerosols is intended to inform appropriate infection control measures to protect health-care workers. Studies of cough aerosols and of exhaled breath from patients with various respiratory infections have shown striking similarities in aerosol size distributions, with a predominance of pathogens in small particles (<5 μm). These are immediately respirable, suggesting the need for personal respiratory protection (respirators) for individuals in close proximity to patients with potentially virulent pathogens. There is no evidence that some pathogens are carried only in large droplets. Surgical masks might offer some respiratory protection from inhalation of infectious aerosols, but not as much as respirators. However, surgical masks worn by patients reduce exposures to infectious aerosols to health-care workers and other individuals. The variability of infectious aerosol production, with some so-called super-emitters producing much higher amounts of infectious aerosol than most, might help to explain the epidemiology of super-spreading. Airborne infection control measures are indicated for potentially lethal respiratory pathogens such as severe acute respiratory syndrome coronavirus 2.
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“Both measured airborne bacteria size distributions in Figure 1 [49,50] span approximately da = 1–10 µm”
From Comparative Mask Protection against Inhaling Wildfire Smoke, Allergenic Bioaerosols, and Infectious Particles (2022) · cites this paper as [49]
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Metadata
- Authors
- Fennelly, K. P.
- Affiliations
- National Institutes of Health (US)
- Corresponding author
- Fennelly, Kevin P
- ORCID
- Fennelly, Kevin P
- Venue
- The Lancet Respiratory Medicine
- Publisher
- Elsevier BV
- Published
- 2020-09
- Volume
- 8
- Issue
- 9
- Pages
- 914-924
- ISSN
- 2213-2600 (ISSN-L)
- PMC
- PMC7380927
- OpenAlex
- W3044072752
- Cited by
- 621
- References
- 145
- Citations by year
- 2026: 42 · 2025: 58 · 2024: 83 · 2023: 75 · 2022: 119 · 2021: 185 · 2020: 59
- FWCI
- 15.48
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- The Lancet Respiratory Medicine (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- reponame:Expeditio Repositorio Institucional UJTL
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Infection Control and Ventilation
- Health Sciences › Dentistry › General Dentistry › Dental Research and COVID-19
- Physical Sciences › Environmental Science › Global and Planetary Change › COVID-19 impact on air quality
- Keywords
- infectious aerosols, aerosol particle size, infection control, healthcare workers, COVID-19 pandemic, SARS-CoV-2, respiratory protection, respirators, surgical masks, cough aerosols, exhaled breath, super-emitters, superspreading, airborne transmission, respiratory pathogens
- MeSH terms
- Betacoronavirus, COVID-19, SARS-CoV-2, Aerosols, Health Personnel, Humans, Particle Size, Pneumonia, Viral, Infection Control, Infectious Disease Transmission, Patient-to-Professional, Coronavirus Infections, Inhalation Exposure, Pandemics
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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