The DOI matches its Crossref record; 78 of the 78 references it cites were found in a registry or an index.
Antidiabetic effects of Momordica charantia (bitter melon) and its medicinal potency
Open accessAbstract
Diabetes mellitus is among the most common disorder in developed and developing countries, and the disease is increasing rapidly in most parts of the world. It has been estimated that up to one-third of patients with diabetes mellitus use some form of complementary and alternative medicine. One plant that has received the most attention for its anti-diabetic properties is bitter melon, Momordica charantia (M. charantia), commonly referred to as bitter gourd, karela and balsam pear. Its fruit is also used for the treatment of diabetes and related conditions amongst the indigenous populations of Asia, South America, India and East Africa. Abundant pre-clinical studies have documented in the anti-diabetic and hypoglycaemic effects of M. charantia through various postulated mechanisms. However, clinical trial data with human subjects are limited and flawed by poor study design and low statistical power. The present review is an attempt to highlight the antidiabetic activity as well as phytochemical and pharmacological reports on M. charantia and calls for better-designed clinical trials to further elucidate its possible therapeutic effects on diabetes.
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Cites
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Cited by
An update on natural compounds in the remedy of diabetes mellitus: A systematic review
Choudhury, H., Pandey, M., Hua, C. K., Mun, C. S., Jing, J. K., Kong, L., Ern, L. Y., Ashraf, N. A., Kit, S. W., Yee, T. S., et al. (2018) · Journal of Traditional and Complementary Medicine · doi:10.1016/j.jtcme.2017.08.012 · Cited by 455
The Role of Momordica charantia in Resisting Obesity
Fan, M., Kim, E.-K., Choi, Y.-J., Tang, Y., & Moon, S.-H. (2019) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph16183251 · Cited by 65
Evaluation of acute and sub-chronic toxicity of bitter melon seed extract in Wistar rats
Chung, W.-Y., Jadhav, S., Hsu, P.-K., & Kuan, C.-M. (2022) · Toxicology Reports · doi:10.1016/j.toxrep.2022.04.024 · Cited by 19
Metadata
- Authors
- Joseph, B., & Jini, D.
- Venue
- Asian Pacific Journal of Tropical Disease
- Publisher
- Elsevier BV
- Published
- 2013-04
- Volume
- 3
- Issue
- 2
- Pages
- 93-102
- ISSN
- 2222-1808 (ISSN-L)
- OpenAlex
- W2077055057
- Cited by
- 511
- References
- 78
- FWCI
- 14.15
- Type
- journal article
- Language
- en
- Open access
- diamond
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- Joseph, B., & Jini, D. (2013). Antidiabetic effects of Momordica charantia (bitter melon) and its medicinal potency. Asian Pacific Journal of Tropical Disease. https://doi.org/10.1016/s2222-1808(13)60052-3
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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