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Cited by 55Gastrointestinal motility and disordersClinical Nutrition and GastroenterologyEnhanced Recovery After Surgery

Nutritional approaches for gastroparesis

Limketkai, Berkeley N, LeBrett, Wendi, Lin, Lisa, Shah, Neha D·2020·The Lancet Gastroenterology & Hepatology
DOI 10.1016/s2468-1253(20)30078-9
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Abstract

Patients with gastroparesis often have signs and symptoms including nausea, vomiting, epigastric discomfort, and early satiety, thus leading to inadequate food intake and a high risk of malnutrition. There is a considerable scarcity of data about nutritional strategies for gastroparesis, and current practices rely on extrapolated evidence. Some approaches include the modification of food composition, food consistency, and food volume in the context of delayed gastric emptying. If the patient is unable to consume adequate calories through a solid food diet, stepwise nutritional interventions could include the use of liquid meals, oral nutrition supplements, enteral nutrition, and parenteral nutrition. This Review discusses the role, rationale, and current evidence of diverse nutritional interventions in the management of gastroparesis.

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Crossref · 10.1016/s2468-1253(20)30078-9

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6 of 6 references verified0 citation errors · 0 not checkable

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  • Liquid or homogenized foods are better tolerated than solids.

    “Liquid or homogenized foods, which are better tolerated than solids [105, 108, 115, 116];”

    From Diabetic gastroparesis: pathophysiology and impact on insulin timing choices (2026) · cites this paper as [105]

  • Small, frequent meals (4-6 per day) reduce gastric distension and symptom burden.

    “Small, frequent meals (4–6 per day) to reduce gastric distension and symptom burden [105, 115–117];”

    From Diabetic gastroparesis: pathophysiology and impact on insulin timing choices (2026) · cites this paper as [105]

  • Nutritional morbidities are common in DGP: nausea, vomiting, early satiety, and postprandial fullness limit food intake and often lead to involuntary weight loss, micronutrient deficiencies (particularly iron, vitamin B12, vitamin D, and fat-soluble vitamins), reduced protein intake, sarcopenia, increased risk of dehydration and hospitalization.

    “Nutritional morbidities are also common: nausea, vomiting, early satiety, and postprandial fullness limit food intake and often lead to involuntary weight loss, micronutrient deficiencies (particularly iron, vitamin B12, vitamin D, and fat-soluble vitamins), reduced protein intake, sarcopenia, increased risk of dehydration and hospitalization [105–108].”

    From Diabetic gastroparesis: pathophysiology and impact on insulin timing choices (2026) · cites this paper as [105]

  • Dietary fat and insoluble fiber delay gastric emptying and exacerbate symptoms.

    “Low‑fat and low‑fiber diets, as dietary fat and insoluble fiber delay gastric emptying and exacerbate symptoms [105, 108, 115, 116];”

    From Diabetic gastroparesis: pathophysiology and impact on insulin timing choices (2026) · cites this paper as [105]

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Authors
Limketkai, B. N., LeBrett, W., Lin, L., & Shah, N. D.
Affiliations
  • University of California, Los Angeles (US)
  • University of California, San Francisco (US)
Corresponding author
Limketkai, Berkeley N
ORCID
Venue
The Lancet Gastroenterology & Hepatology
Publisher
Elsevier BV
Published
2020-11
Volume
5
Issue
11
Pages
1017-1026
ISSN
  • 2468-1156 (ISSN-L)
  • 2468-1253
DOI
10.1016/s2468-1253(20)30078-9
OpenAlex
W3092845186
Cited by
55
References
6
Citations by year
2026: 10 · 2025: 17 · 2024: 8 · 2023: 9 · 2022: 7 · 2021: 4
FWCI
0.87
Type
journal article
Language
en
Open access
closed
Licence
Locations
  • The Lancet. Gastroenterology & hepatology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
  • Health Sciences › Nursing › Nutrition and Dietetics › Clinical Nutrition and Gastroenterology
  • Health Sciences › Medicine › Surgery › Enhanced Recovery After Surgery
Keywords
gastroparesis, dietary management, delayed gastric emptying, malnutrition, food modification, food consistency, liquid meal, oral nutritional supplements, enteral nutrition, parenteral nutrition, nausea and vomiting, early satiety
MeSH terms
Diet Therapy, Humans, Nutritional Support, Gastroparesis, Malnutrition

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