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Statistical Inference as Severe Testing: How to Get Beyond the Statistics Wars
Open accessAbstract
Mounting failures of replication in social and biological sciences give a new urgency to critically appraising proposed reforms. This book pulls back the cover on disagreements between experts charged with restoring integrity to science. It denies two pervasive views of the role of probability in inference: to assign degrees of belief, and to control error rates in a long run. If statistical consumers are unaware of assumptions behind rival evidence reforms, they can't scrutinize the consequences that affect them (in personalized medicine, psychology, etc.). The book sets sail with a simple tool: if little has been done to rule out flaws in inferring a claim, then it has not passed a severe test. Many methods advocated by data experts do not stand up to severe scrutiny and are in tension with successful strategies for blocking or accounting for cherry picking and selective reporting. Through a series of excursions and exhibits, the philosophy and history of inductive inference come alive. Philosophical tools are put to work to solve problems about science and pseudoscience, induction and falsification.
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1 retracted
Genomic signatures to guide the use of chemotherapeutics
Potti, A., Dressman, H. K., Bild, A., Riedel, R. F., Chan, G., Sayer, R. A., Cragun, J. M., Cottrill, H. M., Kelley, M. J., Petersen, R. P., et al. (2006) · Nature Medicine · doi:10.1038/nm1491 · Cited by 595
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Benjamini, Y., & Hochberg, Y. (1995) · Journal of the Royal Statistical Society Series B: Statistical Methodology · doi:10.1111/j.2517-6161.1995.tb02031.x · Cited by 109,482
Bootstrap methods: another look at the jackknife
Efron, B. (1979) · The Annals of Statistics · doi:10.1214/aos/1176344552 · Cited by 17,602
Why Most Published Research Findings Are False
Ioannidis, J. P. A. (2005) · PLoS Medicine · doi:10.1371/journal.pmed.0020124 · Cited by 10,505
Aad, G., Abajyan, T., Abbott, B., Abdallah, J., Khalek, S. A., Abdelalim, A. A., Abdinov, O., Aben, R. Z., Abi, B., Abolins, M., et al. (2012) · Physics Letters B · doi:10.1016/j.physletb.2012.08.020 · Cited by 10,498
Estimating the reproducibility of psychological science
Open Science Collaboration (2015) · Science · doi:10.1126/science.aac4716 · Cited by 8,515
Judgment under Uncertainty: Heuristics and Biases
(1982) · doi:10.1017/cbo9780511809477 · Cited by 8,240
The new frontier of genome engineering with CRISPR-Cas9
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The ASA Statement on p -Values: Context, Process, and Purpose
Wasserstein, R. L., & Lazar, N. A. (2016) · The American Statistician · doi:10.1080/00031305.2016.1154108 · Cited by 6,306
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Self-citation
Metadata
- Authors
- Mayo, D. G.
- Affiliations
- Virginia Tech (US)
- Corresponding author
- Mayo, Deborah G.
- ORCID
- Mayo, Deborah G.
- Venue
- Cambridge University Press eBooks
- Publisher
- Cambridge University Press
- Published
- 2018-09-14
- OpenAlex
- W3171064310
- Cited by
- 376
- References
- 325
- Citations by year
- 2026: 32 · 2025: 57 · 2024: 35 · 2023: 42 · 2022: 60 · 2021: 72 · 2020: 43 · 2019: 28 · 2018: 5
- FWCI
- 54.96
- Type
- book
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Cambridge University Press eBooks (publishedVersion)
- Topics
- Social Sciences › Arts and Humanities › History and Philosophy of Science › Philosophy of Biology and Scientific Explanation
- Social Sciences › Arts and Humanities › History and Philosophy of Science › Logic and Philosophy of Science
- Social Sciences › Arts and Humanities › Philosophy › Literary, Cultural, Historical Analysis
- Keywords
- severe testing, statistical inference, replication crisis, degrees of belief, cherry-picking, selective reporting, inductive reasoning, falsification, pseudoscience, science reform
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