How Much Should We Trust Estimates from Multiplicative Interaction Models? Simple Tools to Improve Empirical Practice
Open accessAbstract
Multiplicative interaction models are widely used in social science to examine whether the relationship between an outcome and an independent variable changes with a moderating variable. Current empirical practice tends to overlook two important problems. First, these models assume a linear interaction effect that changes at a constant rate with the moderator. Second, estimates of the conditional effects of the independent variable can be misleading if there is a lack of common support of the moderator. Replicating 46 interaction effects from 22 recent publications in five top political science journals, we find that these core assumptions often fail in practice, suggesting that a large portion of findings across all political science subfields based on interaction models are fragile and model dependent. We propose a checklist of simple diagnostics to assess the validity of these assumptions and offer flexible estimation strategies that allow for nonlinear interaction effects and safeguard against excessive extrapolation. These statistical routines are available in both R and STATA .
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Cites
Estimating the reproducibility of psychological science
Open Science Collaboration (2015) · Science · doi:10.1126/science.aac4716 · Cited by 8,515 · see citing works
Understanding Interaction Models: Improving Empirical Analyses
Brambor, T., Clark, W. R., & Golder, M. (2006) · Political Analysis · doi:10.1093/pan/mpi014 · Cited by 6,223 · cited 13× · see citing works
“Second, we conducted additional searches to identify all studies published in the APSR and AJPS which included the terms “regression” and “interaction” published since Brambor, Clark, and Golder (2006), roughly 550 articles.”
InfluentialA Practitioner’s Guide to Cluster-Robust Inference
Colin Cameron, A., & Miller, D. L. (2015) · Journal of Human Resources · doi:10.3368/jhr.50.2.317 · Cited by 5,037 · see citing works
Identification, Inference and Sensitivity Analysis for Causal Mediation Effects
Imai, K., Keele, L., & Yamamoto, T. (2010) · Statistical Science · doi:10.1214/10-sts321 · Cited by 1,628 · see citing works
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Martin, E. A., Dainese, M., Clough, Y., Báldi, A., Bommarco, R., Gagic, V., Garratt, M. P. D., Holzschuh, A., Kleijn, D., Kovács‐Hostyánszki, A., et al. (2019) · Ecology Letters · doi:10.1111/ele.13265 · Cited by 648 · see citing works
Chains of Love? Global Production and the Firm‐Level Diffusion of Labor Standards
Malesky, E. J., & Mosley, L. (2018) · American Journal of Political Science · doi:10.1111/ajps.12370 · Cited by 107 · see citing works
The Inseparability of Race and Partisanship in the United States
Westwood, S. J., & Peterson, E. (2022) · Political Behavior · doi:10.1007/s11109-020-09648-9 · Cited by 108 · see citing works
Causal Panel Analysis under Parallel Trends: Lessons from a Large Reanalysis Study
CHIU, A., LAN, X., LIU, Z., & XU, Y. (2026) · American Political Science Review · doi:10.1017/s0003055425000243 · Cited by 48 · see citing works
Self-citationEnvironmental shocks and migration among a climate-vulnerable population in Bangladesh
Freihardt, J. (2025) · Population and Environment · doi:10.1007/s11111-025-00478-7 · Cited by 13 · see citing works
“Hence, I also analyze interactive models (Hainmueller et al., 2019).”
Shaping Police Officer Mindsets and Behaviors: Experimental Evidence of Procedural Justice Training
Canales, R., Santini, J. F., González Magaña, M., & Cherem, A. (2025) · Management Science · doi:10.1287/mnsc.2022.03243 · Cited by 9 · see citing works
- Authors
- Hainmueller, J., Mummolo, J., & Xu, Y.
- Affiliations
- Stanford University (US)
- Princeton University (US)
- University of California San Diego (US)
- Corresponding author
- Hainmueller, Jens
- Venue
- Political Analysis
- Publisher
- Cambridge University Press (CUP)
- Published
- 2018-12-18
- Volume
- 27
- Issue
- 2
- Pages
- 163-192
- ISSN
- 1047-1987 (ISSN-L)
- 1476-4989
- OpenAlex
- W3045058852
- Cited by
- 959
- References
- 4
- Citations by year
- 2026: 106 · 2025: 127 · 2024: 128 · 2023: 117 · 2022: 128 · 2021: 146 · 2020: 121 · 2019: 65 · 2018: 15 · 2017: 6
- FWCI
- 71.99
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Political Analysis (publishedVersion, cc-by-nc-sa)
- Funders
- University of Cambridge
- Topics
- Physical Sciences › Mathematics › Statistics and Probability › Advanced Causal Inference Techniques
- Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Spatial and Panel Data Analysis
- Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods and Bayesian Inference
- Keywords
- multiplicative interaction model, nonlinear interaction effects, moderating effect, conditional effects, common support, model dependence, replication
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