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Transition from squeezing to dripping in a microfluidic T-shaped junction
Open accessAbstract
We describe the results of a numerical investigation of the dynamics of breakup of streams of immiscible fluids in the confined geometry of a microfluidic T-junction. We identify three distinct regimes of formation of droplets: squeezing, dripping and jetting, providing a unifying picture of emulsification processes typical for microfluidic systems. The squeezing mechanism of breakup is particular to microfluidic systems, since the physical confinement of the fluids has pronounced effects on the interfacial dynamics. In this regime, the breakup process is driven chiefly by the buildup of pressure upstream of an emerging droplet and both the dynamics of breakup and the scaling of the sizes of droplets are influenced only very weakly by the value of the capillary number. The dripping regime, while apparently homologous to the unbounded case, is also significantly influenced by the constrained geometry; these effects modify the scaling law for the size of the droplets derived from the balance of interfacial and viscous stresses. Finally, the jetting regime sets in only at very high flow rates, or with low interfacial tension, i.e. higher values of the capillary number, similar to the unbounded case.
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Citations
Cites
Millisecond Kinetics on a Microfluidic Chip Using Nanoliters of Reagents
Song, H., & Ismagilov, R. F. (2003) · Journal of the American Chemical Society · doi:10.1021/ja0354566 · Cited by 693
Cited by
Passive and active droplet generation with microfluidics: a review
Zhu, P., & Wang, L. (2017) · Lab on a Chip · doi:10.1039/c6lc01018k · Cited by 1,238
Seemann, R., Brinkmann, M., Pfohl, T., & Herminghaus, S. (2012) · Reports on Progress in Physics · doi:10.1088/0034-4885/75/1/016601 · Cited by 1,049
Multiphase flow microfluidics for the production of single or multiple emulsions for drug delivery
Zhao, C.-X. (2013) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2013.05.009 · Cited by 451
Dripping and jetting in microfluidic multiphase flows applied to particle and fibre synthesis
Nunes, J. K., Tsai, S. S. H., Wan, J., & Stone, H. A. (2013) · Journal of Physics D: Applied Physics · doi:10.1088/0022-3727/46/11/114002 · Cited by 406
Self-citationIndustrial lab-on-a-chip: Design, applications and scale-up for drug discovery and delivery
Vladisavljević, G. T., Khalid, N., Neves, M. A., Kuroiwa, T., Nakajima, M., Uemura, K., Ichikawa, S., & Kobayashi, I. (2013) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2013.07.017 · Cited by 313
Metadata
- Authors
- DE MENECH, M., GARSTECKI, P., JOUSSE, F., & STONE, H. A.
- Venue
- Journal of Fluid Mechanics
- Publisher
- Cambridge University Press (CUP)
- Published
- 2008-01-08
- Volume
- 595
- Pages
- 141-161
- ISSN
- 0022-1120 (ISSN-L)
- 1469-7645
- OpenAlex
- W2144111110
- Cited by
- 728
- References
- 1
- FWCI
- 20.89
- Type
- journal article
- Language
- en
- Open access
- green
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- DE MENECH, M., GARSTECKI, P., JOUSSE, F., & STONE, H. A. (2008). Transition from squeezing to dripping in a microfluidic T-shaped junction. Journal of Fluid Mechanics. https://doi.org/10.1017/s002211200700910x
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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