The DOI matches its Crossref record; 259 of the 259 references it cites were found in a registry or an index.
Industrial lab-on-a-chip: Design, applications and scale-up for drug discovery and delivery
Open accessAbstract
Microfluidics is an emerging and promising interdisciplinary technology which offers powerful platforms for precise production of novel functional materials (e.g., emulsion droplets, microcapsules, and nanoparticles as drug delivery vehicles- and drug molecules) as well as high-throughput analyses (e.g., bioassays, detection, and diagnostics). In particular, multiphase microfluidics is a rapidly growing technology and has beneficial applications in various fields including biomedicals, chemicals, and foods. In this review, we first describe the fundamentals and latest developments in multiphase microfluidics for producing biocompatible materials that are precisely controlled in size, shape, internal morphology and composition. We next describe some microfluidic applications that synthesize drug molecules, handle biological substances and biological units, and imitate biological organs. We also highlight and discuss design, applications and scale up of droplet- and flow-based microfluidic devices used for drug discovery and delivery.
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Cites
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Cited by
Nanomedicine scale-up technologies: feasibilities and challenges
Paliwal, R., Babu, R. J., & Palakurthi, S. (2014) · AAPS PharmSciTech · doi:10.1208/s12249-014-0177-9 · Cited by 466
Organ-on-a-chip platforms: a convergence of advanced materials, cells, and microscale technologies
Ahadian, S., Civitarese, R., Bannerman, D., Mohammadi, M. H., Lu, R., Wang, E., Davenport‐Huyer, L., Lai, B., Zhang, B., Zhao, Y., et al. (2018) · Advanced Healthcare Materials · doi:10.1002/adhm.201700506 · Cited by 315
Application of flash nanoprecipitation to fabricate poorly water-soluble drug nanoparticles
Tao, J., Chow, S. F., & Zheng, Y. (2019) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2018.11.001 · Cited by 232
Cardiovascular organ-on-a-chip platforms for drug discovery and development
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A review of microfluidic approaches for investigating cancer extravasation during metastasis
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Metadata
- Authors
- Vladisavljević, G. T., Khalid, N., Neves, M. A., Kuroiwa, T., Nakajima, M., Uemura, K., Ichikawa, S., & Kobayashi, I.
- Venue
- Advanced Drug Delivery Reviews
- Publisher
- Elsevier BV
- Published
- 2013-11
- Volume
- 65
- Issue
- 11-12
- Pages
- 1626-1663
- ISSN
- 0169-409X (ISSN-L)
- OpenAlex
- W2071680657
- Cited by
- 313
- References
- 259
- FWCI
- 2.37
- Type
- journal article
- Language
- en
- Open access
- green
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- Vladisavljević, G. T., Khalid, N., Neves, M. A., Kuroiwa, T., Nakajima, M., Uemura, K., Ichikawa, S., & Kobayashi, I. (2013). Industrial lab-on-a-chip: Design, applications and scale-up for drug discovery and delivery. Advanced Drug Delivery Reviews. https://doi.org/10.1016/j.addr.2013.07.017
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
