The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
The Nottingham Study of Neurotic Disorder: predictors of 12-year outcome of dysthymic, panic and generalized anxiety disorder
Abstract
Background. Controlled prospective studies of the simultaneous long-term outcome of several mental disorders are rare. This study sought to determine if there were important differences between the outcome of anxiety and depressive disorders after 12 years and to examine their main predictors. Method. A cohort of 210 people seen in general practice psychiatric clinics with a DSM-III diagnosis of generalized anxiety disorder (71), panic disorder (74), or dysthymic disorder (65), including combined anxiety-depressive disorder (cothymia) (67) was followed up after 12 years. Interview assessments of symptoms, social functioning and outcome were made, the latter using a new scale, the Neurotic Disorder Outcome Scale. Seventeen baseline predictors were also examined. Results. Data were obtained from 201 (96%) patients, 17 of whom had died. Only 73 (36%) had no DSM diagnosis at the time of follow-up. Using univariate and stepwise multiple linear regression those with cothymia, personality disorder, recurrent episodes and greater baseline self-rated anxiety and depression ratings had a worse outcome than others; initial diagnosis did not contribute significantly to outcome and instability of diagnosis over time was much more common than consistency. Conclusion. Only two out of five people with the common neurotic disorders have a good outcome despite alleged advances in treatment. Those with greater mood symptoms and pre-morbid personality disorder have the least favourable outcome. It is suggested that greater attention be paid to the concurrent treatment of personality disorder and environmental factors rather than symptoms as these may be the real cause of apparent treatment resistance.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“These findings are in accordance with other naturalistic long-term follow-up investigations showing high rates of persistent illness and recurrences in dysthymia and panic disorder with agoraphobia [2,3,8].”
From Helpful and hindering factors for remission in dysthymia and panic disorder at 9-year follow-up: A mixed methods study (2008) · cites this paper as [2]
Citations
Cites
The publisher hasn’t deposited this paper’s reference list.
Cited by
Sorted by citations
Items 101–119 of 119
Gale, C. K. (2007) · Evidence-Based Mental Health · doi:10.1136/ebmh.10.2.45 · Cited by 2
Vélez, D. M. A., Gómez, Y., Castro, C. U., et al. (2021) · Revista de Psicología Universidad de Antioquia · doi:10.17533/udea.rp.v12n2a03 · Cited by 2
Psychology University Students’ Mental Health Status during COVID-19 Pandemic in Karachi, Pakistan
Noorullah, A., Mansoor, M., & Zahid, A. (2023) · Open Journal of Psychiatry · doi:10.4236/ojpsych.2023.132006 · Cited by 2
Trivedi, J. K., & Kar, S. K. (2011) · Neuropsychiatry · doi:10.2217/npy.11.23 · Cited by 1
A register-based study of long-term healthcare use before and after psychotherapy
Fenger, M., Mortensen, E. L., Poulsen, S., & Lau, M. E. (2013) · Nordic Journal of Psychiatry · doi:10.3109/08039488.2013.855255 · Cited by 1
Katzman, M. A., Bleau, P., Blier, P., Chokka, P. R., Kjernisted, K. D., & Ameringen, M. V. (2021) · doi:10.32920/14638581.v1 · Cited by 1
Personality in Bulimia Nervosa and Binge Eating Disorder
Rowe, S. L. (2011) · Otago University Research Archive (University of Otago) · Cited by 1
Recovery from dysthymia and panic disorder : Options and obstacles
Svanborg, C. (2008) · Figshare
Are general practitioners unable to diagnose depression? – Author's reply
Tyrer, P. J. (2009) · The Lancet · doi:10.1016/s0140-6736(09)62055-9
Self-citationWspółwystępowanie zaburzeń osobowości i ich wpływ na obraz kliniczny zaburzenia napadowego lęku
Orłowska-Pawliszyn, A., & Landowski, J. (2008) · Cited by 1
Limites de l’approche sémiologique dans le diagnostic des troubles de l’adaptation
Tyrer, P. (2018) · Elsevier eBooks · doi:10.1016/b978-2-294-75659-7.00002-5
Self-citationKapfhammer, H. (2008) · Springer eBooks · doi:10.1007/978-3-540-33129-2_58
Kapfhammer, H. (2011) · Springer eBooks · doi:10.1007/978-3-642-03637-8_57
Pomerantz, D. H., & Naaraayan, A. (2018) · Springer eBooks · doi:10.1007/978-3-319-68379-9_33
Pomerantz, D. H., & Naaraayan, A. (2022) · Springer eBooks · doi:10.1007/978-3-031-15353-2_34
Toledo-Chávarri, A., Ramos‐García, V., Torres‐Castaño, A., Trujillo-Martín, M. M., Peñate Castro, W., Del Cura-Castro, I., Serrano‐Aguilar, P., & Perestelo-Pérez, L. (2020) · Figshare · doi:10.6084/m9.figshare.13269899
Theology and Human Flourishing
(2012) · Emerald Group Publishing Limited eBooks · doi:10.1108/978-1-61735-806-720251006
Understanding Human Flourishing
(2012) · Emerald Group Publishing Limited eBooks · doi:10.1108/978-1-61735-806-720251002
Angst- oder furchtbezogene Störungen
Domschke, K., & Zwanzger, P. (2026) · Springer Reference Medizin · doi:10.1007/978-3-642-45028-0_69-2
Metadata
- Authors
- TYRER, P., SEIVEWRIGHT, H., & JOHNSON, T.
- Affiliations
- MRC Biostatistics Unit (GB)
- Venue
- Psychological Medicine
- Publisher
- Cambridge University Press (CUP)
- Published
- 2004-11
- Volume
- 34
- Issue
- 8
- Pages
- 1385-1394
- ISSN
- 0033-2917 (ISSN-L)
- 1469-8978
- OpenAlex
- W2167393079
- Cited by
- 119
- References
- 0
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 1 · 2023: 3 · 2022: 4 · 2021: 7 · 2020: 4 · 2019: 4 · 2018: 4 · 2017: 7 · 2016: 9 · 2015: 7 · 2014: 5 · 2013: 9 · 2012: 3
- FWCI
- 9.45
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Psychological Medicine (publishedVersion)
- PubMed (publishedVersion)
- Spiral (Imperial College London) (submittedVersion)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
- Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
- Keywords
- neurosis, long-term outcomes, dysthymia, panic disorder, generalized anxiety disorder, personality disorders, prognostic factors, treatment resistance, social functioning
- MeSH terms
- Adult, Female, Follow-Up Studies, Humans, Male, Middle Aged, Prognosis, Recurrence, Cohort Studies, Panic Disorder, Treatment Outcome, Dysthymic Disorder
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
