The DOI matches its Crossref record; 71 of the 71 references it cites were found in a registry or an index.
Clinical and psychosocial outcomes of borderline personality disorder in childhood and adolescence: a systematic review
Abstract
BACKGROUND: While there is a growing body of research on borderline personality disorder (BPD) in children and adolescents, controversy remains regarding the validity and diagnosis of the disorder prior to adulthood. METHOD: MEDLINE, EMBASE, Psych INFO and PubMed databases were systematically searched for articles pertaining to the clinical and psychosocial outcomes (i.e. predictive validity) of BPD first diagnosed in childhood or adolescence (i.e. prior to 19 years of age). All primary empirical studies were included in the review. A narrative synthesis of the data was completed. RESULTS: A total of 8200 abstracts were screened. Out of 214 full-text articles, 18 satisfied the predetermined inclusion criteria. Quality assessment indicated that most studies had high risk of bias in at least one study domain. Consistent with the adult literature, the diagnostic stability of BPD prior to the age of 19 years was low to moderate, and mean-level and rank-order stability, moderate to high. Individuals with BPD symptoms in childhood or adolescence had significant social, educational, work and financial impairment in later life. CONCLUSIONS: Studies indicate that borderline pathology prior to the age of 19 years is predictive of long-term deficits in functioning, and that a considerable proportion of individuals continue to manifest borderline symptoms up to 20 years later. These findings provide some support for the clinical utility of the BPD phenotype in younger populations, and suggest that an early intervention approach may be warranted. Further prospective studies are needed to delineate risk (and protective) factors pertinent to the chronicity of BPD across the lifespan.
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“Research indicates that adolescents who receive timely and appropriate treatment for BPD exhibit better psychological functioning and reduced symptom severity over time (41–43).”
From Age-related differences in borderline personality disorder traits and childhood maltreatment: a cross-sectional study (2025) · cites this paper as [43]
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“As has been observed in the context of conduct disorder and subsequent ASPD, not all children demonstrating conduct problems will manifest ASPD in adulthood (Moffitt & Caspi, 2001).”
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Research works printed but not linked: 3
- 2013, Diagnostic and Statistical Manual of Mental Disorders
- 1980, Diagnostic and Statistical Manual of Mental Disorders
- 1992, The ICD-10 Classification of Mental and Behavioural Disorders: Clinical Description and Diagnostic Guidelines
Cited by
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Borderline personality disorder
Gunderson, J. G., Herpertz, S. C., Skodol, A. E., Torgersen, S. O., & Zanarini, M. C. (2018) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2018.29 · Cited by 511
Winsper, C., Bilgin, A., Thompson, A. D., Marwaha, S., Chanen, A. M., Singh, S. P., Wang, A., & Furtado, V. A. (2019) · The British Journal of Psychiatry · doi:10.1192/bjp.2019.166 · Cited by 406
Borderline personality disorder
Bohus, M., Stoffers‐Winterling, J., Sharp, C., Krause-Utz, A., Schmahl, C., & Lieb, K. (2021) · The Lancet · doi:10.1016/s0140-6736(21)00476-1 · Cited by 388
Eyden, J., Winsper, C., Dieter Wolke, C., Broome, M. R., & MacCallum, F. (2016) · Clinical Psychology Review · doi:10.1016/j.cpr.2016.04.002 · Cited by 196
Winsper, C., Lereya, S. T., Marwaha, S., Thompson, A. D., Eyden, J., & Singh, S. P. (2015) · Clinical Psychology Review · doi:10.1016/j.cpr.2015.12.001 · Cited by 184
Metadata
- Authors
- Winsper, C., Marwaha, S., Lereya, S. T., Thompson, A., Eyden, J., & Singh, S. P.
- Affiliations
- University of Warwick (GB)
- Corresponding author
- Winsper, C.
- Venue
- Psychological Medicine
- Publisher
- Cambridge University Press (CUP)
- Published
- 2015-03-24
- Volume
- 45
- Issue
- 11
- Pages
- 2237-2251
- ISSN
- 0033-2917 (ISSN-L)
- 1469-8978
- OpenAlex
- W2120702185
- Cited by
- 102
- References
- 70
- Citations by year
- 2026: 7 · 2025: 8 · 2024: 9 · 2023: 11 · 2022: 13 · 2021: 12 · 2020: 11 · 2019: 12 · 2018: 6 · 2017: 6 · 2016: 5 · 2015: 2
- FWCI
- 0.91
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Psychological Medicine (publishedVersion)
- PubMed (publishedVersion)
- University of Birmingham Research Portal (University of Birmingham) (submittedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
- Social Sciences › Psychology › Clinical Psychology › Personality Traits and Psychology
- Social Sciences › Psychology › Clinical Psychology › Psychopathy, Forensic Psychiatry, Sexual Offending
- Keywords
- borderline personality disorder, diagnostic stability, predictive validity, long-term functioning, social dysfunction, early intervention
- MeSH terms
- Adolescent, Borderline Personality Disorder, Child, Female, Humans, Male, Diagnostic and Statistical Manual of Mental Disorders
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