PRINCE Secondary: transdiagnostic cognitive behaviour therapy for persistent physical symptoms
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Trials of CBT for persistent physical symptoms, delivered face-to-face or via the internet with therapist support, have taken a transdiagnostic approach, with small-to-moderate positive effects on somatic symptom severity.
“Trials of CBT for persistent physical symptoms, delivered face-to-face or via the internet with therapist support, have taken a transdiagnostic approach, with small-to-moderate positive effects on somatic symptom severity. 90,91”
From Persistent physical symptoms: definition, genesis, and management (2024) · cites this paper as [90]
In “Dear Professor Kendler and Professor Murray” (page unavailable), the authors describe a therapist-delivered transdiagnostic CBT trial and report a small treatment effect in favour of CBT on symptom severity at 12 months. The copy does not describe an internet-delivered trial or establish moderate effects; it also reports no difference on the primary outcome at 52 weeks. (LLM, conf=0.87)
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Cites
Chalder, T., & Willis, C. (2017) · Journal of Mental Health · doi:10.1080/09638237.2017.1322187 · Cited by 59 · see citing works
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Research works printed but not linked: 5
- Bermingham, S. L., Cohen, A., Hague, J., & Parsonage, M. (2010). The cost of somatisation among the working-age population in England for the year 2008-2009. Mental Health in Family Medicine, 7(2), 71-84, Availabe at: http://www.ncbi.nlm.nih.gov/pubmed/22477925. https://doi.org/10.1017/S0033291721003615 Published online by Cambridge University Press
- Chalder, T., Patel, M., Hotopf, M., Moss-Morris, R., Ashworth, M., Watts, K., … Landau, S. (2021). Efficacy of therapist-delivered transdiagnostic CBT for patients with persistent physical symptoms in secondary care: A randomised controlled trial. Psychological Medicine, 1-11. doi: 10.1017/S0033291721001793 · DOI
- Chalder, T., Patel, M., James, K., Hotopf, M., Frank, P., Watts, K., … Landau, S. (2019). Persistent physical symptoms reduction intervention: A system change and evaluation in secondary care (PRINCE secondary) -a CBT-based transdiagnostic approach: Study protocol for a randomised con- trolled trial. BMC Psychiatry, 19(1), 307. doi: 10.1186/s12888-019-2297-y · DOI
- Li, G., Taljaard, M., Van den Heuvel, E. R., Levine, M. A., Cook, D. J., Wells, G. A., … Thabane, L. (2017). An introduction to multiplicity issues in clinical trials: The what, why, when and how. International Journal of Epidemiology, 46(2), 746-755. doi: 10.1093/ije/dyw320 · DOI · Paper page
- Tack, M., & Tuller, D. (2021). PRINCE Secondary: transdiagnostic CBT is not effective for persistent physical symptoms. doi: 10.31219/osf.io/86bkz · DOI
- Authors
- Chalder, T., Patel, M., James, K., Hotopf, M., Moss-Morris, R., Ashworth, M., Watts, K., David, A. S., & Husain, M.
- Affiliations
- King's College London (GB)
- University College London (GB)
- South London and Maudsley NHS Foundation Trust (GB)
- Corresponding author
- Chalder, Trudie
- ORCID
- Venue
- Psychological Medicine
- Publisher
- Cambridge University Press (CUP)
- Published
- 2021-09-07
- Volume
- 53
- Issue
- 7
- Pages
- 3232-3233
- ISSN
- 0033-2917 (ISSN-L)
- 1469-8978
- OpenAlex
- W3197122809
- Cited by
- 1
- References
- 1
- Citations by year
- 2026: 1
- FWCI
- 0.00
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Psychological Medicine (publishedVersion)
- PubMed (publishedVersion)
- Research Portal (King's College London) (submittedVersion, other-oa)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Health Sciences › Medicine › Pharmacology › Musculoskeletal pain and rehabilitation
- Keywords
- persistent physical symptoms, chronic pain, somatic symptoms, princes, secondary prevention
- MeSH terms
- Anxiety Disorders, Depressive Disorder, Humans, Cognitive Behavioral Therapy, Treatment Outcome
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