“Lumping” and “splitting” medically unexplained symptoms: is there a role for a transdiagnostic approach?
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Medically unexplained syndromes (MUS) are defined as persistent bodily symptoms with functional disability but no explanatory pathology. They are highly prevalent in both primary and secondary care...
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At least some of the risk factors and mechanisms leading to the transition from short-term to persistent physical symptoms are common to a variety of conditions, albeit to varying degrees.
“Evidence suggests that at least some of the risk factors and mechanisms leading to the transition from short-term to persistent physical symptoms are common to a variety of conditions, 8,55,63 albeit to varying degrees.”
From Persistent physical symptoms: definition, genesis, and management (2024) · cites this paper as [55]
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- Authors
- Chalder, T., & Willis, C.
- Affiliations
- King's College London (GB)
- Chronic Fatigue Research and Treatment Unit, London, UK
- Corresponding author
- Chalder, Trudie
- ORCID
- Chalder, Trudie
- Venue
- Journal of Mental Health
- Publisher
- Informa UK Limited
- Published
- 2017-05-04
- Volume
- 26
- Issue
- 3
- Pages
- 187-191
- ISSN
- 0963-8237 (ISSN-L)
- 1360-0567
- OpenAlex
- W2604496176
- Semantic Scholar
- 7d62d525208d900297077401e2bcbbbd4efa67a0
- Cited by
- 59
- References
- 30
- Citations by year
- 2026: 6 · 2025: 9 · 2024: 9 · 2023: 5 · 2022: 7 · 2021: 12 · 2020: 3 · 2019: 5 · 2018: 3
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Mental Health (publishedVersion)
- PubMed (publishedVersion)
- Research Portal (King's College London) (submittedVersion, other-oa)
- Funders
- South London and Maudsley NHS Foundation Trust
- National Institute for Health and Care Research
- King's College London
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Health Sciences › Medicine › Psychiatry and Mental health › Fibromyalgia and Chronic Fatigue Syndrome Research
- Health Sciences › Medicine › Psychiatry and Mental health › Medicine, History, and Philosophy
- Keywords
- medically unexplained symptoms, transdiagnostic approach, lumping and splitting, functional disability, somatic symptoms, primary care, secondary care
- MeSH terms
- Medically Unexplained Symptoms, Mental Disorders, Humans, Fatigue Syndrome, Chronic
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