The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Structural features of cytochrome oxidase
Abstract
This article tries to be a compact summary of some recent research on cytochrome c oxidase (EC 1.9.3.1), an important enzyme in membrane bioenergetics. Cytochrome oxidase is the terminal catalyst of the mitochondrial respiratory chain. It uses the electrons flowing through the chain to reduce oxygen molecules to water. Four electrons and four protons are consumed in the reduction of O 2 to two molecules of water (Fig. 1). Cytochrome oxidase contains four redoxactive metal centres. Two of these are copper atoms, two haem A groups. These four centres are employed in the dioxygen-binding site and in the electron-transferring pathways from cytochrome c. The enzyme is also called cytochrome aa3, because the protein-bound haems are functionally and spectroscopically different.
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Citations
Cites
The relation between the divergence of sequence and structure in proteins.
Chothia, C., & Lesk, A. M. (1986) · The EMBO Journal · doi:10.1002/j.1460-2075.1986.tb04288.x · Cited by 2,458
Anderson, S., de Bruijn, M. H. L., Coulson, A. R., Eperon, I. C., Sanger, F., & Young, I. G. (1982) · Journal of Molecular Biology · doi:10.1016/0022-2836(82)90137-1 · Cited by 1,472
Cited by
Oxidative Phosphorylation at the fin de siècle
Saraste, M. (1999) · Science · doi:10.1126/science.283.5407.1488 · Cited by 1,313
Self-citationBerks, B. C., Ferguson, S. J., Moir, J. W. B., & Richardson, D. J. (1995) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/0005-2728(95)00092-5 · Cited by 596
Cytochrome c oxidase deficiency
Shoubridge, E. A. (2001) · American Journal of Medical Genetics · doi:10.1002/ajmg.1378 · Cited by 323
Fearnley, I. M., & Walker, J. E. (1992) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/0005-2728(92)90001-i · Cited by 311
Mitochondrial copper metabolism and delivery to cytochrome c oxidase
Horn, D., & Barrientos, A. (2008) · IUBMB Life · doi:10.1002/iub.50 · Cited by 283
Metadata
- Authors
- Saraste, M.
- Venue
- Quarterly Reviews of Biophysics
- Publisher
- Cambridge University Press (CUP)
- Published
- 1990-11
- Volume
- 23
- Issue
- 4
- Pages
- 331-366
- ISSN
- 0033-5835 (ISSN-L)
- 1469-8994
- OpenAlex
- W2147148910
- Cited by
- 402
- References
- 2
- FWCI
- 2.51
- Type
- journal article
- Language
- en
- Open access
- closed
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- Saraste, M. (1990). Structural features of cytochrome oxidase. Quarterly Reviews of Biophysics. https://doi.org/10.1017/s0033583500005588
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
