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Cited by 43Antifungal resistance and susceptibilityCentral Venous Catheters and HemodialysisInfective Endocarditis Diagnosis and Management

Candidal Suppurative Peripheral Thrombophlebitis Recognition, Prevention, and Management

Walsh, Thomas J., Bustamente, Carlos I., Vlahov, David, Standiford, Harold C.·1986·Infection Control
DOI 10.1017/s0195941700063736
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Abstract

Candida species are seldom considered as a cause of suppurative peripheral thrombophlebitis. During a 15-month period in a 291-bed acute-care hospital, candidal suppurative peripheral thrombophlebitis developed in seven patients. All patients had fever, a tender palpable cord, and Candida species isolated from resected veins and/or pus expressed at the catheter entrance site. Four patients had candidemia. None were neutropenic or recipients of corticosteroids. All had concomitant or preceding bacterial infections, and had received a median of 5 antibiotics (range 3 to 9) for at least 2 weeks. Five of seven had documented preceding candidal colonization associated with broad spectrum antibiotic therapy. Catheter sites had not been routinely rotated and local catheter site care was deficient. Risk factors of antibiotics and duration of hospitalization were fewer in patients with bacterial suppurative thrombophlebitis. Combined segmental venous resection and intravenous amphotericin B appears to be the most rational therapy for this nosocomial fungal infection.

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Crossref · 10.1017/s0195941700063736

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  • Suppurative peripheral thrombophlebitis responds to surgical resection of the infected vein and antifungal therapy with amphotericin B or fluconazole.

    “Suppurative peripheral thrombophlebitis responds to surgical resection of the infected vein and antifungal therapy with amphotericin B or fluconazole [223].”

    From Guidelines for Treatment of Candidiasis (2004) · cites this paper as [223]

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Authors
Walsh, T. J., Bustamente, C. I., Vlahov, D., & Standiford, H. C.
Affiliations
University of Maryland, Baltimore (US)
Corresponding author
Standiford, Harold C.
ORCID
Venue
Infection Control
Publisher
Cambridge University Press (CUP)
Published
1986-01
Volume
7
Issue
1
Pages
16-22
ISSN
  • 0195-9417 (ISSN-L)
  • 2327-9451
DOI
10.1017/s0195941700063736
OpenAlex
W2282744910
Cited by
43
References
26
Citations by year
2015: 1 · 2012: 1
FWCI
2.60
Type
journal article
Language
en
Open access
closed
Licence
www.cambridge.org/core/terms (unspecified, 10593 d)
Locations
  • Infection Control (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
  • Health Sciences › Health Professions › Emergency Medical Services › Central Venous Catheters and Hemodialysis
  • Health Sciences › Medicine › Epidemiology › Infective Endocarditis Diagnosis and Management
Keywords
Candida species, catheter-related infection, nosocomial fungal infections, candidemia, amphotericin B, risk factors, nosocomial infections
MeSH terms
Aged, Amphotericin B, Candidiasis, Catheterization, Humans, Male, Middle Aged, Suppuration, Thrombophlebitis

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