The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.
The use of Arginine Vasopressin in neonates following the Norwood procedure
Abstract
Background Following the Norwood palliation, neonates may require an escalation of inotropic and vasoactive support. Arginine Vasopressin may be uniquely useful in supporting this population. Materials and methods A retrospective evaluation of neonates at this institution between November, 2007 and October, 2010 who received Arginine Vasopressin following the Norwood procedure. Data were recorded from the patient records at one hour prior to, and then 1, 2, 3, 4, 6, and 24 hours following Arginine Vasopressin initiation. Results We included 28 neonates. The mean dose of Arginine Vasopressin was 0.0005 plus or minus 0.0003 units per kilogram per minute. There was an early response (less than 6 hours) characterised by an 8% increase in systolic blood pressure (p = 0.0004), a 100% increase in urine output (p = 0.02), and a 29% decrease in total fluid administration (p = 0.04). The late response (at 24 hours) revealed further increases in systolic blood pressure and urine output as well as a 53% decrease in serum lactate (p = 0.007) and increase in arterial pH from 7.36 to 7.45 (p less than 0.0001). These changes were not accompanied by increases in heart rate or inotrope score. Conclusions The initiation of Arginine Vasopressin in post-operative Norwood patients was temporally associated with an improvement in markers of perfusion including systolic blood pressure, urine output, lactate, and pH. Further studies are required to ascertain the efficacy of Arginine Vasopressin in th…
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“Vasopressin, an endogenous hormone produced in the hypothalamus, has recently been applied to children with refractory hypotension due to vasoplegia after cardiac surgery [13-15].”
From Management of the Low Cardiac Output Syndrome Following Surgery for Congenital Heart Disease (2016) · cites this paper as [14]
In the citing paper
“Other studies have also demonstrated a decrease need for fluid and catecholamine requirements and improved blood pressure after complex heart surgery in neonates with the use of vasopressin [14, 15].”
From Management of the Low Cardiac Output Syndrome Following Surgery for Congenital Heart Disease (2016) · cites this paper as [14]
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Intravenous Arginine-Vasopressin in Children With Vasodilatory Shock After Cardiac Surgery
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Vasopressin in Pediatric Vasodilatory Shock: A Multicenter Randomized Controlled Trial
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Regulation of Na+ channels in the cortical collecting duct by AVP and mineralocorticoids
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Signal transduction of V1-vascular vasopressin receptors
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Prevention of Early Sudden Circulatory Collapse After the Norwood Operation
Oliveira, N. C. D., Ashburn, D. A., Khalid, F., Burkhart, H. M., Adatia, I., Holtby, H. M., Williams, W. G., & Arsdell, G. S. V. (2004) · Circulation · doi:10.1161/01.cir.0000138399.30587.8e · Cited by 100
Physiology of the vasopressin receptors
Maybauer, M. O., Maybauer, D. M., Enkhbaatar, P., & Traber, D. L. (2008) · Best practice & research. Clinical anaesthesiology · doi:10.1016/j.bpa.2008.03.003 · Cited by 91
Arginine-vasopressin in neonates with vasodilatory shock after cardiopulmonary bypass
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P2 purinergic receptor activation enhances cardiac contractility in isolated rat and mouse hearts
Mei, Q., & Liang, B. T. (2001) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.2001.281.1.h334 · Cited by 52
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Relative deficiency of arginine vasopressin in children after cardiopulmonary bypass*
Mastropietro, C. W., Rossi, N. F., Clark, J. A., Chen, H., Walters, H., Delius, R., Lieh-Lai, M., & Sarnaik, A. P. (2010) · Critical Care Medicine · doi:10.1097/ccm.0b013e3181eed91d · Cited by 34
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Terlipressin for Children with Extremely Low Cardiac Output After Open Heart Surgery
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Cited by
Management of the Low Cardiac Output Syndrome Following Surgery for Congenital Heart Disease
K. Chandler, H., & Kirsch, R. (2016) · Current Cardiology Reviews · doi:10.2174/1573403x12666151119164647 · Cited by 74
“Vasopressin, an endogenous hormone produced in the hypothalamus, has recently been applied to children with refractory hypotension due to vasoplegia after cardiac surgery [13-15].”
BackgroundCumulative Corticosteroid Exposure and Infection Risk After Complex Pediatric Cardiac Surgery
Mastropietro, C. W., Barrett, R., Davalos, M. C., Zidan, M., Valentine, K. M., Delius, R. E., & Walters, H. L. (2013) · The Annals of Thoracic Surgery · doi:10.1016/j.athoracsur.2013.02.026 · Cited by 42
Metadata
- Authors
- Burton, G. L., Kaufman, J., Goot, B. H., & da Cruz, E. M.
- Affiliations
- Children's Hospital Colorado (US)
- Corresponding author
- da Cruz, Eduardo M.
- Venue
- Cardiology in the Young
- Publisher
- Cambridge University Press (CUP)
- Published
- 2011-04-19
- Volume
- 21
- Issue
- 5
- Pages
- 536-544
- ISSN
- 1047-9511 (ISSN-L)
- 1467-1107
- OpenAlex
- W2130570922
- Cited by
- 35
- References
- 18
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 3 · 2023: 4 · 2022: 4 · 2021: 3 · 2020: 3 · 2019: 1 · 2018: 1 · 2017: 3 · 2016: 2 · 2014: 3 · 2013: 3 · 2012: 2
- FWCI
- 1.92
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Cardiology in the Young (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Congenital Heart Disease Studies
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Cardiovascular Conditions and Treatments
- Health Sciences › Medicine › Surgery › Hemodynamic Monitoring and Therapy
- Keywords
- vasopressin, Norwood procedure, neonates, hypoplastic left heart syndrome, vasoactive support, inotropic support, hemodynamic response, urine output, serum lactate, arterial pH, systolic blood pressure, postoperative care
- MeSH terms
- Arginine Vasopressin, Female, Humans, Infant, Newborn, Male, Postoperative Care, Retrospective Studies, Vasoconstrictor Agents, Norwood Procedures
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