Diagnosis of congenital heart disease in an era of universal prenatal ultrasound screening in southwest Ohio
Abstract
OBJECTIVES: Diagnostic ultrasound is widespread in obstetric practice, yet many babies with major congenital heart disease remain undiagnosed. Factors affecting prenatal diagnosis of major congenital heart disease are not well understood. This study aims to document prenatal detection rates for major congenital heart disease in the Greater Cincinnati area, and identify factors associated with lack of prenatal diagnosis. METHODS: All living infants diagnosed with major congenital heart disease by 4 months of age at our centre were prospectively identified. Prenatal care data were obtained by parent interview. Neonatal records were reviewed for postnatal data. Obstetricians were contacted for diagnostic ultrasound data. RESULTS: A total of 100 infants met the inclusion criteria. In all, 95 infants were analysed, of whom 94 were offered diagnostic ultrasound. In all, 41 had a prenatal diagnosis of major congenital heart disease. The rate of prenatal detection varied by cardiac lesion, with aortic arch abnormalities, semilunar valve abnormalities, and venous anomalies going undetected in this sample. Among subjects without prenatal detection, the highest proportion consisted of those having Level 1 diagnostic ultrasound only (66%). Prenatal detection was not significantly influenced by maternal race, education level, income, or insurance type. CONCLUSIONS: Despite nearly universal diagnostic ultrasound, detection rates of major congenital heart disease remain low in southwest Ohio. An educational outreach programme including outflow tract sweeps for community-level obstetrical personnel may improve detection rates.
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It is not always possible to detect CHDs manually through ultrasound.
“Through US, CHDs can be detected manually. However, it is not always possible to detect CHDs in this way [7,8].”
From Deep Learning for Improving the Effectiveness of Routine Prenatal Screening for Major Congenital Heart Diseases (2022) · cites this paper as [7]
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Self-citation
- Authors
- Sekar, P., Heydarian, H. C., Cnota, J. F., Hornberger, L. K., & Michelfelder, E. C.
- Affiliations
- Cincinnati Children's Hospital Medical Center (US)
- University of Alberta (CA)
- Corresponding author
- Sekar, Priya
- Venue
- Cardiology in the Young
- Publisher
- Cambridge University Press (CUP)
- Published
- 2013-10-10
- Volume
- 25
- Issue
- 1
- Pages
- 35-41
- ISSN
- 1047-9511 (ISSN-L)
- 1467-1107
- OpenAlex
- W2058259755
- Cited by
- 23
- References
- 36
- Citations by year
- 2026: 1 · 2024: 2 · 2023: 1 · 2022: 3 · 2021: 4 · 2020: 2 · 2019: 2 · 2018: 4 · 2017: 2 · 2015: 2
- FWCI
- 0.49
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Cardiology in the Young (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Congenital Heart Disease Studies
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Prenatal Screening and Diagnostics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Congenital heart defects research
- Keywords
- congenital heart disease, prenatal diagnosis, prenatal ultrasound screening, ultrasonography, missed diagnosis, venous anomalies, obstetric training
- MeSH terms
- Female, Heart Defects, Congenital, Humans, Ohio, Pregnancy, Prenatal Care, Prenatal Diagnosis, Retrospective Studies, Risk Factors, Ultrasonography, Prenatal
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