Practical guide for prescribing MAOIs: debunking myths and removing barriers
Abstract
Despite the fact that monoamine oxidase inhibitors (MAOIs) can be highly effective therapeutic agents for depression and some anxiety disorders, they tend to be underutilized in clinical practice. This is due at least in part to the fact that there is a great deal of misinformation and mythology about their dietary and drug interactions. This article is intended to serve as a guide for clinicians who are not particularly familiar with MAO inhibitors; its aim is to help these clinicians competently integrate these agents into clinical practice when appropriate.
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Safety was a big concern with MAOIs because fatal hypertensive crises could occur if large amounts of tyramine was obtained from food.
“Safety was a big concern with MAOIs because fatal hypertensive crises could occur if large amounts of tyramine was obtained from food.”
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- Authors
- Grady, M. M., & Stahl, S. M.
- Affiliations
- Neuroscience Education Institute (US)
- University of Cambridge (GB)
- Corresponding author
- Grady, Meghan M.
- ORCID
- Stahl, Stephen M.
- Venue
- CNS Spectrums
- Publisher
- Cambridge University Press (CUP)
- Published
- 2012-04-26
- Volume
- 17
- Issue
- 1
- Pages
- 2-10
- ISSN
- 1092-8529 (ISSN-L)
- 2165-6509
- OpenAlex
- W2074703267
- Cited by
- 51
- References
- 46
- Citations by year
- 2025: 1 · 2023: 2 · 2022: 6 · 2021: 8 · 2019: 3 · 2018: 3 · 2017: 7 · 2016: 6 · 2015: 5 · 2014: 3 · 2013: 5 · 2012: 1
- FWCI
- 3.29
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- CNS Spectrums (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Health Sciences › Medicine › Psychiatry and Mental health › Electroconvulsive Therapy Studies
- Keywords
- monoamine oxidase inhibitors, depression, anxiety disorders, dietary restriction, drug interactions
- MeSH terms
- Anxiety Disorders, Depression, Drug Interactions, Humans, Monoamine Oxidase Inhibitors, Guidelines as Topic
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