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Cited by 33Skin and Cellular Biology ResearchRetinal Development and DisordersConnexins and lens biology

Foveolar Müller Cells of the Pied Flycatcher: Morphology and Distribution of Intermediate Filaments Regarding Cell Transparency

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Zueva, Lidia, Golubeva, Tatiana, Korneeva, Elena, Makarov, Vladimir, Khmelinskii, Igor, Inyushin, Mikhail·2016·Microscopy and Microanalysis
DOI 10.1017/s1431927616000507PMC PMC4940978
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Abstract

Specialized intermediate filaments (IFs) have critical importance for the clearness and uncommon transparency of vertebrate lens fiber cells, although the physical mechanisms involved are poorly understood. Recently, an unusual low-scattering light transport was also described in retinal Müller cells. Exploring the function of IFs in Müller cells, we have studied the morphology and distribution pattern of IFs and other cytoskeletal filaments inside the Müller cell main processes in the foveolar part of the avian (pied flycatcher) retina. We found that some IFs surrounded by globular nanoparticles (that we suggest are crystallines) are present in almost every part of the Müller cells that span the retina, including the microvilli. Unlike IFs implicated in the mechanical architecture of the cell, these IFs are not connected to any specific cellular membranes. Instead, they are organized into bundles, passing inside the cell from the endfeet to the photoreceptor, following the geometry of the processes, and repeatedly circumventing numerous obstacles. We believe that the presently reported data effectively confirm that the model of nanooptical channels built of the IFs may provide a viable explanation of Müller cell transparency.

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  • Transparency in animals is a complex form of camouflage involving mechanisms that reduce light scattering and absorption throughout the organism.

    “Transparency in animals is a complex form of camouflage involving mechanisms that reduce light scattering and absorption throughout the organism.”

    From Glassfrogs conceal blood in their liver to maintain transparency (2022) · cites this paper as [3]

    The Introduction (page unavailable) says tissue is transparent when it neither absorbs nor scatters light and discusses how cellular structures affect scattering. But the paper concerns transparent eye cells, not transparency as camouflage or mechanisms operating throughout an animal’s body. (LLM, conf=0.85)

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Research works printed but not linked: 38

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Authors
Zueva, L., Golubeva, T., Korneeva, E., Makarov, V., Khmelinskii, I., & Inyushin, M.
Affiliations
  • Russian Academy of Sciences (RU)
  • University of Puerto Rico System (PR)
  • University of Algarve (PT)
  • Central University of the Caribbean (PR)
Corresponding author
Inyushin, Mikhail
ORCID
Venue
Microscopy and Microanalysis
Publisher
Oxford University Press (OUP)
Published
2016-03-01
Volume
22
Issue
2
Pages
379-386
ISSN
  • 1431-9276 (ISSN-L)
  • 1435-8115
DOI
10.1017/s1431927616000507
PMC
PMC4940978
OpenAlex
W2289054036
Cited by
33
References
0
Citations by year
2025: 1 · 2024: 1 · 2023: 2 · 2022: 5 · 2021: 4 · 2020: 4 · 2019: 9 · 2018: 4 · 2017: 2 · 2016: 1
FWCI
3.05
Type
journal article
Language
en
Open access
Licence
www.cambridge.org/core/terms (unspecified)
Locations
  • Microscopy and Microanalysis (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
  • Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT) (submittedVersion, other-oa)
Funders
  • National Center for Research Resources (G12RR003035)
  • National Institute on Minority Health and Health Disparities (G12MD007583)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Skin and Cellular Biology Research
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Retinal Development and Disorders
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Connexins and lens biology
Keywords
Müller cells, intermediate filaments, fovea, Ficedula hypoleuca, avian retina, cytoskeleton, light scattering, microvilli, crystalline nanoparticles, retinal pigment epithelium
MeSH terms
Animals, Intermediate Filaments, Retina, Songbirds, Biophysical Phenomena, Ependymoglial Cells

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