Cited by 389Bipolar Disorder and TreatmentPersonality Disorders and PsychopathologyMental Health Research Topics

The DOI matches its Crossref record; 29 of the 30 references it cites were found in a registry or an index.

Long-term symptomatic status of bipolar I vs. bipolar II disorders

Open access

Judd, Lewis L., Schettler, Pamela J., Akiskal, Hagop S., Maser, Jack, Coryell, William, Solomon, David, Endicott, Jean, Keller, Martin·2003·The International Journal of Neuropsychopharmacology

DOI 10.1017/s1461145703003341

Open this paper in CoChat — free account Open PDF

Abstract

Weekly affective symptom severity and polarity were compared in 135 bipolar I (BP I) and 71 bipolar II (BP II) patients during up to 20 yr of prospective symptomatic follow-up. The course of BP I and BP II was chronic; patients were symptomatic approximately half of all follow-up weeks (BP I 46.6% and BP II 55.8% of weeks). Most bipolar disorder research has concentrated on episodes of MDD and mania and yet minor and subsyndromal symptoms are three times more common during the long-term course. Weeks with depressive symptoms predominated over manichypomanic symptoms in both disorders (31) in BP I and BP II at 371 in a largely depressive course (depressive symptoms=59.1% of weeks vs. hypomanic=1.9% of weeks). BP I patients had more weeks of cyclingmixed polarity, hypomanic and subsyndromal hypomanic symptoms. Weekly symptom severity and polarity fluctuated frequently within the same bipolar patient, in which the longitudinal symptomatic expression of BP I and BP II is dimensional in nature involving all levels of affective symptom severity of mania and depression. Although BP I is more severe, BP II with its intensely chronic depressive features is not simply the lesser of the bipolar disorders; it is also a serious illness, more so than previously thought (for instance, as described in DSM-IV and ICP-10). It is likely that this conventional view is the reason why BP II patients were prescribed pharmacological treatments significantly less often when acutely symptomatic and during intervals between episodes. Taken together with previous research by us on the long-term structure of unipolar depression, we submit that the thrust of our work during the past decade supports classic notions of a broader affective disorder spectrum, bringing bipolarity and recurrent unipolarity closer together. However the genetic variation underlying such a putative spectrum remains to be clarified.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1017/s1461145703003341

Cites

29 of 29 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

MANIC DEPRESSIVE ILLNESS
Davenport, Y. B., Adland, M. L., Gold, P. W., & Goodwin, F. K. (1984) · The Lancet · doi:10.1016/s0140-6736(84)92810-1 · Cited by 2,925
The Long-term Natural History of the Weekly Symptomatic Status of Bipolar I Disorder
Judd, L. L., Akiskal, H. S., Schettler, P. J., Endicott, J., Maser, J., Solomon, D. A., Leon, A. C., Rice, J. A., & Keller, M. B. (2002) · Archives of General Psychiatry · doi:10.1001/archpsyc.59.6.530 · Cited by 2,106
Self-citation
The Longitudinal Interval Follow-up Evaluation: A Comprehensive Method for Assessing Outcome in Prospective Longitudinal Studies
Keller, M. B. (1987) · Archives of General Psychiatry · doi:10.1001/archpsyc.1987.01800180050009 · Cited by 1,643
Self-citation
Manic-depressive illness
Papageorgis, D. (1991) · Behaviour Research and Therapy · doi:10.1016/0005-7967(91)90087-j · Cited by 1,537
A Prospective Investigation of the Natural History of the Long-term Weekly Symptomatic Status of Bipolar II Disorder
Judd, L. L., Akiskal, H. S., Schettler, P. J., Coryell, W., Endicott, J., Maser, J. D., Solomon, D. A., Leon, A. C., & Keller, M. B. (2003) · Archives of General Psychiatry · doi:10.1001/archpsyc.60.3.261 · Cited by 1,243
Self-citation
A Family Study of Schizoaffective, Bipolar I, Bipolar II, Unipolar, and Normal Control Probands
Gershon, E. S. (1982) · Archives of General Psychiatry · doi:10.1001/archpsyc.1982.04290100031006 · Cited by 987
A prospective 12-year study of subsyndromal and syndromal depressive symptoms in unipolar major depressive disorders
Judd, L. L., Akiskal, H. S., Maser, J. D., Zeller, P. J., Endicott, J., Coryell, W., Paulus, M. P., Kunovac, J. L., Leon, A. C., Mueller, T. I., et al. (1998) · Archives of General Psychiatry · doi:10.1001/archpsyc.55.8.694 · Cited by 775
Self-citation
Manic depressive illness
Goodwin, F. K., & Jamison, K. R. (2007) · Cited by 534
Subaffective Disorders: Dysthymic, Cyclothymic and Bipolar II Disorders in the “;Borderline” Realm
Akiskal, H. S. (1981) · Psychiatric Clinics of North America · doi:10.1016/s0193-953x(18)30935-3 · Cited by 508
Self-citation
Course of the Manic-Depressive Cycle and Changes Caused by Treatments
Kukopulos, A., Reginaldi, D., Laddomada, P., Floris, G., Serra, G., & Tondo, L. (2008) · Pharmacopsychiatry · doi:10.1055/s-2007-1019628 · Cited by 436 · cited 1×
“Previous studies of bipolar disorders have focused almost exclusively on full syndromal episodes of major depression (MDE) and mania (e.g. Angst, 1986; Cassano et al., 1989; Coryell et al., 1984; Koukopoulos et al., 1980; Winokur et al., 1994).”
Background

Show all 30 references

Research works printed but not linked: 2

[2]2. Akiskal HS (1983). The bipolar spectrum: new concepts in classification and Diagnosis. In : Grinspoon L (Ed.), Psychiatry Update: The American Psychiatric Association Annual Review, vol. 2 (pp. 271-292). Washington, DC : American Psychiatric Press.
[9]9. Endicott J, Nee J, Andreasen N, Clayton P, Keller M, Coryell W (1985). Bipolar II. Combine or keep separate? Journal of Affective Disorders 8, 17-28.

Sorted by citations

Items 301–389 of 389

Personality Pathology Predicts Outcomes in a Treatment-Seeking Sample with Bipolar I Disorder
Wenze, S. J., Gaudiano, B. A., Weinstock, L. M., & Miller, I. W. (2014) · Depression Research and Treatment · doi:10.1155/2014/816524 · Cited by 2
Bipolar Spectrum Disorder: Origins and State of the Art
Tamayo, J. M., Cossio, C., Florez, M. C., Tamayo-Calle, J., Marulanda, D., Mejia, C., Gómez, N. P., Gomez, A., Duque-Ochoa, S., Alvarez-Arboleda, L. M., et al. (2013) · Current Psychiatry Reviews · doi:10.2174/157340013805289653 · Cited by 2
Bipolarité : de la maladie maniaco-dépressive au trouble bipolaire
Allilaire, J. (2004) · Bulletin de l Académie Nationale de Médecine · doi:10.1016/s0001-4079(19)33803-8 · Cited by 2
Quality of life in caregivers of patients with bipolar mood disorder with current manic episode and its correlation with severity of illness
Panigrahi, S., Acharya, R. K., Patel, M. K. P. M. K., & Chandrani, K. V. (2014) · IOSR Journal of Dental and Medical Sciences · doi:10.9790/0853-13824851 · Cited by 2
Lower Switch Rate in Depressed Patients With Bipolar II Than Bipolar I Disorder Treated Adjunctively With Second-Generation Antidepressants
Altshuler, L. L., Suppes, T. M., Black, D. O., Nolen, W. A., Leverich, G. S., Keck, P. E., Frye, M. A., Kupka, R., McElroy, S. L., Grunze, H., et al. (2007) · FOCUS The Journal of Lifelong Learning in Psychiatry · doi:10.1176/foc.5.1.107 · Cited by 2
The Role of Antidepressants in Bipolar Disorder
Yerevanian, B. I. (2011) · Wiley eBooks · doi:10.1002/9780470975114.ch15 · Cited by 2
Gender and depressive symptoms in 711 patients with bipolar disorder evaluated prospectively in the Stanley Foundation Bipolar Treatment Network
Altshuler, L. L., Kupka, R., Hellemann, G., Frye, M. A., Grunze, H., Keck, P. E., Leverich, G. S., McElroy, S. L., Nolen, W. A., Sugar, C. A., et al. (n.d.) · University of Groningen research database (University of Groningen / Centre for Information Technology) · Cited by 2
Diagnostic Identity and the Legitimisation of Mental Health Problems: An Ethnographic Study with a focus on Bipolar Disorder
Lane, R. (2019) · ORCA Online Research @Cardiff (Cardiff University) · doi:10.13140/rg.2.2.27055.59049 · Cited by 2
Course of illness and the development of vascular disease in individuals with bipolar disorder
Fiedorowicz, J. G. (2011) · doi:10.17077/etd.iu2e0wkq · Cited by 2
Health states for schizophrenia and bipolar disorder within the Global Burden of Disease 2010 Study
Ferrari, A. J., Saha, S., McGrath, J. J., Norman, R., Baxter, A. J., Vos, T., & Whiteford, H. A. (2012) · Population Health Metrics · doi:10.1186/1478-7954-10-16 · Cited by 1
Bipolar Disorders in Chinese Culture: From a Perspective of Harmony
Shen, C., Jia, Y., & Wang, W. (2019) · Springer eBooks · doi:10.1007/978-981-13-3537-2_9 · Cited by 1
Knowledge, attitudes, and willingness of bipolar disorder patients toward electroconvulsive therapy: a cross-sectional study
Zhou, L., Qi, X., Xu, L., Duanmu, X., Wang, K., Liu, K., & Zhang, Y. (2025) · Frontiers in Public Health · doi:10.3389/fpubh.2025.1572046 · Cited by 1
Clinical Phenomenology of Bipolar Disorder With Substance Use Disorders: A Systematic Review
Garvie, S., Sorkhou, M., & George, T. P. (2026) · Bipolar Disorders · doi:10.1111/bdi.70132 · Cited by 1
Prevalence and outcomes of real-world bipolar depression patients underrepresented in guideline RCTs
Fornaro, M., Lorenzo, C. D., Sarto, V., Zeoli, E. L., Pascucci, E., Ferraioli, G., Passeretti, A., Pariano, R., Iasevoli, F., & de Bartolomeis, A. (2026) · Journal of Affective Disorders · doi:10.1016/j.jad.2026.122363 · Cited by 1
Patients with bipolar disorder in a bipolar clinic setting: practical steps
Young, A. H., & Hale, A. S. (2013) · Acta Psychiatrica Scandinavica · doi:10.1111/acps.12120 · Cited by 1
A Procedure to Graph the Quality of Psychosocial Functioning Affected by Symptom Severity
McCullough, J. P., Clark, S. W., Klein, D. N., & First, M. B. (2016) · American Journal of Psychotherapy · doi:10.1176/appi.psychotherapy.2016.70.2.222 · Cited by 1
Actualización en el uso y el manejo del litio en neuropsiquiatría
Corrales, A., Cetkovich, M., Abadi, A. F., Camino, S., Bonetto, G. G., Mato, A. M. L., Marengo, E., Abraham, E., Maresca, T., Bagnati, P. R. A. D. N., et al. (2024) · Vertex Revista Argentina de Psiquiatría · doi:10.53680/vertex.v34i162.504 · Cited by 2
Treatment of Refractory Bipolar Depression With Stereotactic Radiosurgery Targeting the Subgenual Cingulate Cortex
Solvason, H. B., Marianayagam, N. J., Soltys, S. G., Schatzberg, A. F., DeBattista, C., Ketter, T. A., Wang, P. W., Chang, S. D., Spiegel, D., & Adler, J. R. (2024) · Cureus · doi:10.7759/cureus.57904 · Cited by 1
Pharmacological treatment of acute bipolar depression
Sachs, G. S., Sylvia, L. G., & Lund, H. G. (2009) · Birkhäuser Basel eBooks · doi:10.1007/978-3-7643-8567-5_9 · Cited by 1
Bipolar Illness
Coryell, W. H., & Clayton, P. J. (2016) · Springer eBooks · doi:10.1007/978-1-4939-2528-5_4 · Cited by 1
Self-citation
Perspectives on the Measurement of Outcome
Strober, M., & Lock, J. (2015) · doi:10.1002/9781118574089.ch64 · Cited by 2
Electroconvulsive therapy for bipolar disorder depression. Effects on depressive symptoms and cognitive function
Keßler, U. (2014) · NORA - Norwegian Open Research Archives · Cited by 1
Ensaio clínico randomizado, duplo-cego, controlado com placebo, de monoidrato de creatina como terapia adjuvante na depressão bipolar
Toniolo, R. A. (2016) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.5.2016.tde-07122016-150647 · Cited by 1
Mood Stabilisers, but for Lithium, are not stabilizing Moods! Bipolar Disorders: Clinical conundrums 2
Reddy, M. S. S., Mythri, S. V., & Reddy, S. (2017) · Indian Journal of Psychological Medicine · doi:10.4103/ijpsym.ijpsym_427_17 · Cited by 1
Mood Disorders
Hammen, C. L., & Keenan‐Miller, D. (2012) · Wiley eBooks · doi:10.1002/9781118133880.hop208005 · Cited by 1
"Twenty wasted years” Exploring the experience of misdiagnosis within Bipolar Type Two disorder"
Smith, N. (2018) · e-space (Manchester Metropolitan University) · Cited by 1
Recognition, comorbidity, and outcome of DSM-IV bipolar I and II disorders in psychiatric care
Mantere, O. (2007) · Työväentutkimus Vuosikirja · Cited by 1
Los límites de los trastornos del espectro depresivo.
Guimón, J. (2005) · Avances en Salud Mental Relacional
Funcionament psicosocial en el trastom bipolar: Factors implicats i seguiment als 4 anys
Roig, B., & del Mar, C. (2011) · Dipòsit Digital de la Universitat de Barcelona (Universitat de Barcelona)
Bipolar Disorder in the Family: Impact on Functioning and Adjustment to College
Crandall, E. K. (2011) · doi:10.12794/metadc84195
Practical Pharmacological Maintenance Treatment of Bipolar Disorder
Swann, A. C. (2010) · Wiley eBooks · doi:10.1002/9780470661277.ch24
双極性障害の早期診断と治療(シンポジウム:うつ病の診断・治療上の問題点とコツ,2008年,第49回日本心身医学会総会(札幌))
輝明, 田., & 司, 小. (2009) · 心身医学 · doi:10.15064/jjpm.49.9_979
Bipolar disorder: Strategies for the lifelong illness
Swann, A. C. (2006) · Current Psychosis & Therapeutics Reports · doi:10.1007/bf02629388
New developments in the bipolar spectrum conceptualization
Lieberman, D. Z., & Goodwin, F. K. (2003) · Current Psychosis & Therapeutics Reports · doi:10.1007/bf02629384
Long-Term Health Outcome of Adolescent Mood Disorders : Focus on Bipolar Disorder
Päären, A. (2015) · KTH Publication Database DiVA (KTH Royal Institute of Technology)
P01-49 - The Study Protocol of the Norwegian Randomized Controlled Trial of Electroconvulsive Therapy in Treatment Resistant Depression in Bipolar Disorder
Keßler, U., Schoeyen, H. K., Vaaler, A., Ødegaard, K. J., Bergsholm, P., Andreassen, O. A., Malt, U. F., & Morken, G. (2010) · European Psychiatry · doi:10.1016/s0924-9338(10)70268-6
Considering long-term outcome and tolerability in the treatment of bipolar disorder
Adson, D. E. (2004) · Current Psychosis & Therapeutics Reports · doi:10.1007/bf02629432
Introduction to the Special Section New advances in the understanding and treatment of bipolar disorder
Souery, D., & Mendlewicz, J. (2003) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145703003444
Subsyndromal Depressive Symptoms in Bipolar II Disorder: a Community Mental Health Services Cohort Study (SIN-DEPRES)
de Arce, R., Jiménez‐Arriero, M. Á., Rodríguez-Calvin, J. L., Ruiz-Aguado, J. M., Domingo, S. Z., Cobaleda, S., & Vieta, E. (2011) · Revista Colombiana de Psiquiatría · doi:10.1016/s0034-7450(14)60192-x
Clear indications of emotion depend on vivid stimuli
Zihl, J. (2004) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.2004.048009
Clinical Perspectives: Mindfulness-Based Cognitive Therapy and Mood Disorders
Willett, B. R., & Lau, M. A. (2015) · Springer eBooks · doi:10.1007/978-1-4939-2263-5_13
Epidemiological Assessment of Bipolar Disorder in Canada
McDonald, K. C. (2015) · Libraries and Cultural Resources (University of Calgary) · doi:10.11575/prism/25924
UNIVERSIDADE DO EXTREMO SUL CATARINENSE - UNESC UNIDADE ACADÊMICA DE CIÊNCIAS DA SAÚDE PROGRAMA DE PÓS-GRADUAÇÃO EM CIÊNCIAS DA SAÚDE DOUTORADO EM CIÊNCIAS DA SAÚDE
Valvassori, S. D. S. (2013)
Lower Switch Rate in Depressed Patients With Bipolar II Than Bipolar I Disorder Treated Adjunctively With Second-Generation
Altshuler, L. L., Suppes, T. M., Nolen, W. A., Leverich, G. S., Frye, M. A., Kupka, R., McElroy, S. L., & Grunze, H. (2007)
The dilemma in the concept and the management of bipolar disorder
Okasha, A. (2011) · Middle East Current Psychiatry · doi:10.1097/01.xme.0000405314.98496.3f
Psychopharmacology of mood disorders
Coryell, W. H., & Geddes, J. R. (2008) · Cambridge University Press eBooks · doi:10.1017/cbo9780511544392.029
Self-citation
Risk factors that influence suicidal behavior in affective disorders
Stanojević, A., Nenadović, M., Milosevic, D., & Popovic, I. (2016) · Praxis medica · doi:10.5937/pramed1601023s
The Longitudinal Course of Adolescent Bipolar Disorder as Revealed Through Weekly Self-Report, Using Internet and Text-Messaging-Based Mood Monitoring
Bopp, J. M. (2014) · CU Scholar (University of Colorado Boulder)
MoodSwings: an online self-guided intervention for bipolar disorder
Lauder, S. D. (2016) · Minerva Access (University of Melbourne)
Association between a Genetic Variant of CACNA1C and the Risk of Schizophrenia and Bipolar I Disorder Across Diagnostic Boundaries
Lee, B., Baek, J. H., Cho, E. Y., Yang, S.-Y., Choi, Y. J., Lee, Y. S., Ha, K., & Hong, K. S. (2018) · Korean Journal of Schizophrenia Research · doi:10.16946/kjsr.2018.21.2.43
Tratamento da depressão bipolar com estimulação transcraniana por corrente contínua: ensaio clínico aleatorizado, duplo-cego, placebo-controlado
Júnior, B. D. S. P. (2018) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.5.2018.tde-02082018-102334
Brain Structure and Function in Emotion Processing, Emotion Regulation, and Reward Processing Neural Circuitries in Offspring at Risk for Bipolar Disorder
Acuff, H. E. (2018) · D-Scholarship@Pitt (University of Pittsburgh)
Purulent Appendicular Peritonitis in Pregnancy: Management and Pregnancy Outcome
Juan, P. (2019) · Archives in Biomedical Engineering & Biotechnology · doi:10.33552/abeb.2018.01.000507
Estudo da Inflamação no Transtorno Afetivo Bipolar:
dos Santos, M. G., Faria, M. B. G., Borges, K. D. S., Júnior, A. L. T., & Sousa, L. P. (2014) · Revista Neurociências · doi:10.4181/rnc.2014.22.898.10p
The Diagnosis of Adult ADHD Toward a Precision Psychiatry Approach
Pallanti, S., & Salerno, L. (2020) · Springer eBooks · doi:10.1007/978-3-030-39051-8_5
L'effet du trouble bipolaire I et du trouble dépressif majeur sur le fonctionnement de la main-d'oeuvre
McIntyre, R. S., Wilkins, K., Gilmour, H., Soczynska, J. K., Konarksi, J. Z., Miranda, A., Woldeyohannes, H. O., Vagic, D., Alsuwaiden, M., & Kennedy, S. H. (2008) · Maladies chroniques au Canada · doi:10.24095/hpcdp.28.3.01f
Ways of coping and problem solving in individuals with bipolar affective disorder: A gender comparison
Singh, M., Singh, U. P., & Kiran, M. (2020) · International Journal of Psychiatry Research · doi:10.33545/26648962.2020.v2.i2a.26
Bipolar disorder and cardiovascular dysfunction: Mechanisms and implications
Mio, M., & Goldstein, B. I. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-819182-8.00019-3
The biological basis of predominant polarity
Pacchiarotti, I., Anmella, G., & Vieta, E. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-819182-8.00008-9
Independence of Mania and Depression across 4 Years in Bipolar Disorder
Bennett, C. B. (2019) · University of North Texas Digital Library (University of North Texas) · doi:10.12794/metadc1505184
Electroconvulsive therapy for preventing relapse and recurrence in bipolar disorder
Munkholm, K., Jørgensen, K. J., & Paludan‐Müller, A. S. (2021) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd015172
Electroconvulsive therapy for acute affective episodes in people with bipolar disorder
Munkholm, K., Jørgensen, K. J., & Paludan‐Müller, A. S. (2021) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd014996
References
Lam, D. H., Jones, S. H., & Hayward, P. (2010) · Wiley eBooks · doi:10.1002/9780470970256.refs
The heterogeneous early illness courses of Korean patients with bipolar disorders – replication of the stage modelPreprint
Lee, Y., Lee, D., Jung, H., Cho, Y., Baek, J. H., & Hong, K. S. (2022) · Research Square · doi:10.21203/rs.3.rs-1403711/v1
Childhood Trauma and Sleep-related Daytime Dysfunction in Patients with Bipolar II Disorder
Lu, T., Hsieh, Y., Lin, S., Yang, Y. K., & Chen, P. S. (2022) · Taiwanese Journal of Psychiatry · doi:10.4103/tpsy.tpsy_4_22
Functional brain imaging in bipolar disorder
Kirsch, D. E., Tretyak, V., Strakowski, S. M., & Lippard, E. (2022) · Oxford University Press eBooks · doi:10.1093/med/9780197574522.003.0003
Pharmacological Treatment of Acute Bipolar Depression
Sachs, G. S. (2016) · Milestones in drug therapy · doi:10.1007/978-3-319-31689-5_9
Bipolar Disorder
Reiser, R. (2015) · Wiley eBooks · doi:10.1002/9781118521373.wbeaa136
Mood Stabilizers
(2019) · American Psychiatric Association Publishing eBooks · doi:10.1176/appi.books.9781615372997.as05
Mood Stabilizers
(2019) · American Psychiatric Association Publishing eBooks · doi:10.1176/appi.books.9781615372300.as05
Tercer Consenso Argentino sobre el manejo de los Trastornos Bipolares. Segunda Parte A: Tratamiento integral de los trastornos bipolares en el adulto
Cetkovich, M., Abadi, A. F., Camino, S., Bonetto, G. G., Herbst, L., Marengo, E., Torrente, F. M., Maresca, T., Bustin, J., Morra, C. A., et al. (2023) · Vertex Revista Argentina de Psiquiatría · doi:10.53680/vertex.v34i159.363
Economic Evaluation of Mental Health Interventions
Jin, H., Jalali, A., Wijnen, B. F. M., & Bao, Y. (2023) · Frontiers research topics · doi:10.3389/978-2-8325-3692-6
References
(2016) · Wiley eBooks · doi:10.1002/9781394259472.refs
Chapter 5. Mood Stabilizers
(2024) · American Psychiatric Association Publishing eBooks · doi:10.1176/appi.books.9798894551289.cd05
Transtorno bipolar: uma doença heterogênea que requer uma perspectiva mais ampla de abordagem
Moreno, R. A., Campos, R. N., & Moreno, D. H. (2012) · Debates em Psiquiatria · doi:10.25118/2763-9037.2012.v2.899
Strategies for managing and addressing challenges in individuals with bipolar affective disorder: A comparison between genders
Dahal, T., & Abraham, J. (2024) · IP Indian Journal of Neurosciences · doi:10.18231/j.ijn.2024.030
La période de rémission chez les patients bipolaires
Duranté, E. K., & Henry, C. (2023) · Elsevier eBooks · doi:10.1016/b978-2-294-77180-4.00010-x
Lithium versus cariprazine in the acute phase treatment for depressive episodes in patients with bipolar disorder: a protocol for a pragmatic open, randomised multicentre study – the 9th trial of the Danish University Antidepressant Group, DUAG-9
Hovgesen, S. V., Licht, R. W., Straszek, S. P. V., Christensen, A.-E., Vinberg, M., Videbech, P., Miskowiak, K. W., Johnsen, S., Munk, M. M., Linnart, M., et al. (2025) · BMJ Open · doi:10.1136/bmjopen-2025-102406
Validity of the bipolar spectrum in depression
MacIntyre, D. J. (2013) · ERA
Additional file 1 of Clinical characteristic of prodromal symptoms between bipolar I and II disorder among Chinese patients: a retrospective study
Zhao, Q., Guo, T., Li, Y., Zhang, L., Lyu, N., Wilson, A. D., Zhu, X., & Li, X. (2021) · Figshare · doi:10.6084/m9.figshare.14707987
Additional file 1 of Decreased dynamic variability of the cerebellum in the euthymic patients with bipolar disorder
Chen, Z., Zhang, Z., Li, F., Zhao, L., 薄奇静, Zhou, Y., & Wang, C. (2024) · Figshare · doi:10.6084/m9.figshare.26682757
Patient‐Reported Outcomes From a Randomized Controlled Trial Comparing Right Unilateral Electroconvulsive Therapy With Algorithm‐Based Pharmacological Treatment in Bipolar Depression, With Long‐Term Follow‐Up on Pharmacological Treatment
Bjørke, J., Schøyen, H., Vaaler, A., Auestad, B., Malt, U., Morken, G., Oedegaard, K., Andreassen, O. A., Bergsholm, P., & Kessler, U. (2026) · Bipolar Disorders · doi:10.1111/bdi.70105
Multi-nuclear RMN in Spectroscopy and Imagery at very high magnetic fields
Stout, J. A. (2019) · theses.fr (ABES) · doi:10.70675/e54ad71az8f87z4c42z9f45z1ddc59f3aac1
Animal models that mirror bipolar disorder’s pathophysiologic complexities: focused review of common models
Yassa, R., Ibrahim, M., & El‐Mallakh, R. S. (2026) · Expert Opinion on Drug Discovery · doi:10.1080/17460441.2026.2671292
Thyroid hormone augmentation for bipolar disorder: a neurobiological and clinical narrative review
Ibrahim, M., Bhutto, U. F., Yassa, R., & El‐Mallakh, R. S. (2026) · International Journal of Bipolar Disorders · doi:10.1186/s40345-026-00429-7
Working memory network dysfunction in bipolar I vs. bipolar II disorder: a systematic review of task-fMRI evidence
Yu, H., Wang, T., Wang, Y., Liang, J., Zou, Q., Xiang, J., Lu, Y., & Liu, K. (2026) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2026.1800042
Efficacy, acceptability, and related outcomes of pharmacological interventions for acute bipolar depression: A systematic review and dose-related network meta-analysis across different age groups
Fornaro, M., Lorenzo, C. D., Oliva, V., Prisco, M. D., & Vieta, E. (2026) · Journal of Affective Disorders · doi:10.1016/j.jad.2026.122160
Remote monitoring of patient status in bipolar disorder: scientific and practical rationale for launching an electronic system; a validation clinical study protocol
Kostyukova, E. G., Pervaya, D. V., & Mosolov, S. N. (2026) · Neurology Bulletin · doi:10.17816/nb702649 · Cited by 1
Context-dependent facial-expression patterns during affective film viewing in patients with bipolar depressionPreprint
Lee, E., Sim, S. H., Park, C., Kim, H., Ahn, W., & Park, C. H. K. (2026) · medRxiv · doi:10.64898/2026.07.19.26358451

Authors: Judd, L. L., Schettler, P. J., Akiskal, H. S., Maser, J., Coryell, W., Solomon, D., Endicott, J., & Keller, M.
Affiliations: University of California San Diego (US)
National Institute of Mental Health (US)
Corresponding author: Judd, Lewis L.
ORCID: Schettler, Pamela J.
Coryell, William
Keller, Martin
Venue: The International Journal of Neuropsychopharmacology
Publisher: Oxford University Press (OUP)
Published: 2003-06
Volume: 6
Issue: 2
Pages: 127-137
ISSN: 1461-1457 (ISSN-L)
1469-5111
DOI: 10.1017/s1461145703003341
OpenAlex: W2119349901
Cited by: 389
References: 30
Citations by year: 2026: 9 · 2025: 7 · 2024: 17 · 2023: 10 · 2022: 14 · 2021: 11 · 2020: 15 · 2019: 27 · 2018: 18 · 2017: 15 · 2016: 22 · 2015: 21 · 2014: 23 · 2013: 22 · 2012: 24
FWCI: 8.57
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: The International Journal of Neuropsychopharmacology (publishedVersion)
PubMed (publishedVersion)
Funders: University of California, San Diego
National Institute of Mental Health (R01MH025478)
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
Social Sciences › Psychology › Experimental and Cognitive Psychology › Mental Health Research Topics
Keywords: bipolar I disorder, bipolar II disorder, depressive symptoms, hypomanic symptoms, subsyndromal symptoms, chronic depression, major depressive disorder
MeSH terms: Adolescent, Adult, Aged, Bipolar Disorder, Female, Follow-Up Studies, Humans, Long-Term Care, Male, Middle Aged, Psychiatric Status Rating Scales

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Long-term symptomatic status of bipolar I vs. bipolar II disorders

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks