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Cited by 188

The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.

Developmental programming of cardiovascular disease by prenatal hypoxia

Open access
Giussani, D. A., Davidge, S. T.·2013·Journal of Developmental Origins of Health and Disease

Abstract

It is now recognized that the quality of the fetal environment during early development is important in programming cardiovascular health and disease in later life. Fetal hypoxia is one of the most common consequences of complicated pregnancies worldwide. However, in contrast to the extensive research effort on pregnancy affected by maternal nutrition or maternal stress, the contribution of pregnancy affected by fetal chronic hypoxia to developmental programming is only recently becoming delineated and established. This review discusses the increasing body of evidence supporting the programming of cardiac susceptibility to ischaemia and reperfusion (I/R) injury, of endothelial dysfunction in peripheral resistance circulations, and of indices of the metabolic syndrome in adult offspring of hypoxic pregnancy. An additional focus of the review is the identification of plausible mechanisms and the implementation of maternal and early life interventions to protect against adverse programming.

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Metadata

Authors
Giussani, D. A., & Davidge, S. T.
Venue
Journal of Developmental Origins of Health and Disease
Published
2013-04-18
Volume
4
Issue
5
Pages
328-337
ISSN
  • 2040-1744 (ISSN-L)
  • 2040-1752
OpenAlex
W2130981336
Cited by
188
References
10
FWCI
12.02
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Developmental programming of cardiovascular disease by prenatal hypoxia. https://app.cochat.ai/papers/10.1017/s204017441300010x
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Giussani, D. A., & Davidge, S. T. (2013). Developmental programming of cardiovascular disease by prenatal hypoxia. Journal of Developmental Origins of Health and Disease. https://doi.org/10.1017/s204017441300010x

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.