The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Multiplex Biosensor Using Gold Nanorods
Abstract
Gold nanorods (GNRs) with different aspect ratios were fabricated through seed-mediated growth and surface activation by alkanethiols for the attachment of antibodies to yield gold nanorod molecular probes (GNrMPs). Multiplex sensing was demonstrated by the distinct response of the plasmon spectra of the GNrMPs to binding events of three targets (goat anti-human IgG1 Fab, rabbit anti-mouse IgG1 Fab, rabbit anti-sheep IgG (H+L)). Plasmonic sensors are highly specific and sensitive and can be used to monitor refractive index changes caused by molecular interactions in their immediate vicinity with potential to achieve single-particle biosensing. This technique can play a key role in developing novel optical biosensors for both in vivo and in vitro detection and single-receptor kinetics.
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Cites
Haes, A. J., & Van Duyne, R. P. (2002) · Journal of the American Chemical Society · doi:10.1021/ja020393x · Cited by 2,057
Cited by
Localized Surface Plasmon Resonance Sensors
Mayer, K. M., & Hafner, J. H. (2011) · Chemical Reviews · doi:10.1021/cr100313v · Cited by 4,350
Gold Nanorods: From Synthesis and Properties to Biological and Biomedical Applications
Huang, X., Neretina, S., & El‐Sayed, M. A. (2009) · Advanced Materials · doi:10.1002/adma.200802789 · Cited by 1,921
Localized surface plasmon resonance: Nanostructures, bioassays and biosensing—A review
Petryayeva, E., & Krull, U. J. (2011) · Analytica Chimica Acta · doi:10.1016/j.aca.2011.08.020 · Cited by 1,379
Plasmonic coupling in noble metal nanostructures
Jain, P. K., & El-Sayed, M. A. (2010) · Chemical Physics Letters · doi:10.1016/j.cplett.2010.01.062 · Cited by 963
Gold nanorod-based localized surface plasmon resonance biosensors: A review
Cao, J., Sun, T., & Grattan, K. T. V. (2014) · Sensors and Actuators B: Chemical · doi:10.1016/j.snb.2014.01.056 · Cited by 768
Metadata
- Authors
- Yu, C., & Irudayaraj, J.
- Venue
- Analytical Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2006-12-16
- Volume
- 79
- Issue
- 2
- Pages
- 572-579
- ISSN
- 0003-2700 (ISSN-L)
- 1520-6882
- OpenAlex
- W1978369328
- Cited by
- 511
- References
- 1
- FWCI
- 16.50
- Type
- journal article
- Language
- en
- Open access
- closed
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