Micro Total Bioassay System for Ingested Substances: Assessment of Intestinal Absorption, Hepatic Metabolism, and Bioactivity

Imura, Yuki, Sato, Kiichi, Yoshimura, Etsuro·2010·Analytical Chemistry
DOI 10.1021/ac100806x

Cited by (173)

Items 101–173 of 173

  1. Biology coming full circle: Joining the whole and the parts
    John P. Wikswo, Andrew P Porter · 2015 · Experimental Biology and Medicine
  2. Emerging Three-Dimensional Hepatic Models in Relation to Traditional Two-Dimensional In Vitro Assays for Evaluating Drug Metabolism and Hepatoxicity
    Erin Milner, Michael Ainsworth, Matthew McDonough, Benjamin D. Stevens, Johannah Buehrer, Richard Delzell, Cameron Wilson, Jason C. Barnhill · 2020 · Medicine in Drug Discovery
  3. High-Throughput Incubation and Quantification of Agglutination Assays in a Microfluidic System
    David Castro, David Conchouso, Rimantas Kodzius, Arpys Arevalo, Ian G. Foulds · 2018 · Genes
  4. PDMS microstencil plate-supported fabrication of ultra-thin, condensed ECM membranes for separated cell coculture on both surfaces
    Hideki Iwadate, Masumi Yamada, Naoki Kimura, Rina Hashimoto, Yuya Yajima, Rie Utoh, Minoru Seki · 2019 · Sensors and Actuators B Chemical
  5. Materials and Microenvironments for Engineering the Intestinal Epithelium
    Jessica R. Snyder, Chia-Ming Wang, An Qi Zhang, Yuan Li, Joshua Luchan, Sanjin Hosic, Ryan A. Koppes, Rebecca Lyn Carrier, Abigail N. Koppes · 2020 · Annals of Biomedical Engineering
  6. Bioreactors in tissue engineering: mimicking the microenvironment
    Ece Bayır, Mert Şahinler, M. Mert Celtikoglu, Aylin Şendemir · 2020 · Elsevier eBooks
  7. Application of chemical reaction engineering principles to “body‐on‐a‐chip” systems
    Jong Hwan Sung, Ying I. Wang, Jung Hun Kim, Jong Min Lee, Michael Louis Shuler · 2018 · AIChE Journal
  8. Passive-Flow-Based MPS: Emerging Physiological Flow-Mimetic Platforms for Studying Effects of Flow on Single Tissues and Inter-tissue Interactions
    Geonho Jin, Dohyung Kim, Seonghun Mun, Seokyoung Bang · 2024 · BioChip Journal
  9. Improving Risk Assessment
    Donna M. Dambach, Hirdesh Uppal · 2012 · Science Translational Medicine
  10. Cell-patterned glass spray for direct drug assay using mass spectrometry
    Jing Wu, Shiqi Wang, Qiushui Chen, Hao Jiang, Shuping Liang, Jin‐Ming Lin · 2015 · Analytica Chimica Acta
  11. Organomimetic microsystems technologies
    Jiheum Park, Kwang Bok Kim, Jungchul Lee, Hee Chan Kim, Dongeun Huh · 2012 · Biomedical Engineering Letters
  12. Cells and Organs on Chip—A Revolutionary Platform for Biomedicine
    Preeti Nigam Joshi · 2016 · InTech eBooks
  13. Bioengineered human gut-on-a-chip for advancing non-clinical pharmaco-toxicology
    Yong Cheol Shin, Nam Than, Soo Jin Park, Hyun Jung Kim · 2024 · Expert Opinion on Drug Metabolism & Toxicology
  14. Microfluidic Reconstitution of Tumor Microenvironment for Nanomedical Applications
    Hyun Jeong Oh, Jaehoon Kim, Hyunho Kim, Nakwon Choi, Seok Hwan Chung · 2021 · Advanced Healthcare Materials
  15. A Review of the Application of Body-on-a-Chip for Drug Test and Its Latest Trend of Incorporating Barrier Tissue
    Haoyi Jin, Yanqiu Yu · 2015 · SLAS TECHNOLOGY
  16. Fabrication of Hollow Structures in Photodegradable Hydrogels Using a Multi-Photon Excitation Process for Blood Vessel Tissue Engineering
    Uran Watanabe, Shinji Sugiura, Masayuki Kakehata, Fumiki Yanagawa, Toshiyuki Takagi, Kimio Sumaru, Taku Satoh, Masato Tamura, Yoichiroh Hosokawa, Kenji Torizuka et al. · 2020 · Micromachines
  17. The promise of organotypic hepatic and gastrointestinal models
    Lucas T. Vu, Rebekah R. Less, Padmavathy Rajagopalan · 2014 · Trends in biotechnology
  18. Integrative microphysiological tissue systems of cancer metastasis to the liver
    Amanda M. Clark, Nancy L. Allbritton, Alan H. Wells · 2020 · Seminars in Cancer Biology
  19. Validation of Bioreactor and Human-on-a-Chip Devices for Chemical Safety Assessment
    Sofia P. Rebelo, Eva‐Maria Dehne, Catarina Brito, Reyk Horland, Paula M. Alves, Uwe Marx · 2016 · Advances in experimental medicine and biology
  20. Development of a Perfusing Small Intestine–Liver Microphysiological System Device
    Yoko Sakai, Masanari Matsumura, Hideki Yamada, Atsushi Doi, Isao Saito, Takahiro Iwao, Tamihide Matsunaga · 2023 · Applied Sciences
  21. Development of a Multichannel Dialysis Microchip for Bioassay of Drug Efficacy and Retention
    Yu Sakuta, Kin‐ichi Tsunoda, Kiichi Sato · 2017 · Analytical Sciences
  22. Unlocking the future: converging multi-organ-on-a-chip on the current biomedical sciences
    Sayan Basak · 2020 · Emergent Materials
  23. Cell Culture on Low-Fluorescence and High-Resolution Photoresist
    Hidetaka Ueno, Katsuya Maruo, Masatoshi Inoue, Hidetoshi Kotera, Takaaki Suzuki · 2020 · Micromachines
  24. Bio–Microfabrication of 2D and 3D Biomimetic Gut-on-a-Chip
    Yeongseok Jang, Jinmu Jung, Jonghyun Oh · 2023 · Micromachines
  25. Versatile membrane-based microfluidic platform for in vitro drug diffusion testing mimicking in vivo environments
    Oihane Mitxelena‐Iribarren, Claudia Olaizola‐Rodrigo, Sergio Arana, Maite Mujika · 2021 · Nanomedicine Nanotechnology Biology and Medicine
  26. The Application of New Approach Methodologies in Respiratory Disease Research: Their Role in Improving Translational Medicine from Bench to Bedside
    Artur Christian Garcia da Silva, Marize Campos Valadares · 2023 · Alternatives to Laboratory Animals
  27. Design and engineering of multiorgan systems
    Kasper Renggli, Olivier Frey · 2019 · Elsevier eBooks
  28. Three‐dimensional in vitro cell culture devices using patient‐derived cells for high‐throughput screening of drug combinations
    Seok‐Joon Kwon, Dongwoo Lee, Sneha Gopal, Ashlyn Ku, Hosang Moon, Jonathan S. Dordick · 2020 · Medical Devices & Sensors
  29. Tumor Models and Cancer Systems Biology for the Investigation of Anticancer Drugs and Resistance Development
    Erica Aparecida de Oliveira, Colin R. Goding, Silvya Stuchi Maria–Engler · 2020 · Handbook of experimental pharmacology
  30. Gut-on-a-chip microphysiological systems for the recapitulation of the gut microenvironment
    Seung Hwan Lee, Jong Hwan Sung · 2019 · Elsevier eBooks
  31. Lab-on-a-chip techniques for high-throughput proteomics and drug discovery
    Nauman Khalid, Sania Arif, Isao Kobayashi, Mitsutoshi Nakajima · 2018 · Elsevier eBooks
  32. Progress in ‘body-on-a-chip’ research
    Jens M. Kelm, Rosemarie Marchan · 2014 · Archives of Toxicology
  33. Exploring microfluidics-based organoid interactions through analysis of albumin secretion
    Yang Yang, Yueyang Qu, Jing Wang, Yuxiu Wang, Jiamin Zhao, Miaomiao Wang, Wanqing Hu, Jiaqi Zhao, Bingcheng Lin, Xiuli Zhang et al. · 2025 · Lab on a Chip
  34. Microfluidics – Organ-on-chip
    Iulia Ioana Lungu, Alexandru Mihai Grumezescu · 2019 · Biomedical Engineering International
  35. Three Dimensional In Vitro Tumor Platforms for Cancer Discovery
    Manasa Gadde, Dan Marrinan, Rhys James Michna, Marissa Nichole Rylander · 2017 · Cancer drug discovery and develogment/Cancer drug discovery and development
  36. On-Chip modeling of drug-gut interactions in Oral drug delivery
    Sorosh Abdollahi, Fereshteh Vajhadin, Atefeh Rafiei, Sara Hassanpour Tamrin, Shine David Daniel, Mohammad Mehdi Banoei, Bahareh Zarin, Arindom Sen, Keekyoung Kim, Amir Sanati‐Nezhad · 2026 · Advanced Drug Delivery Reviews
  37. Multiorgan-on-a-chip: Design and Applications
    Hiba Khan, Sara Akhtar Khan, Suhel Parvez · 2024 · Elsevier eBooks
  38. Microfluidic devices and their applicability to cell studies
    Ana Carolina Fernandes, Daria Semenova, Inês P.R. Grundtvig · 2023 · Elsevier eBooks
  39. Designer substrates and devices for mechanobiology study
    Wang Xi, Delphine Delacour, Benoît Ladoux · 2020 · Journal of Semiconductors
  40. Microphysiological systems for modeling gut-organ interaction
    Jong Hwan Sung · 2024 · Biocell
  41. Microfluidic Cell Culture Techniques
    Yun Xiao, Boyang Zhang, Anne Hsieh, Nimalan Thavandiran, Cristina Martin, Milica Radisic · 2012 · Elsevier eBooks
  42. Intelligent Biomaterials and Microfluidic Technology
    Cherie S. Tan, Mingxuan He, Yongde Guo, Jingyu Fu · 2025 · Springer eBooks
  43. Navigating Drug Dynamics: Unleashing On-Chip Pharmacokinetics and Pharmacodynamics
    Anish Kumar Das, Rakesh Mutukuri, Neelanjan Chowdhury, David Paul, Satheesh Kumar Nanjappan · 2025 · Drug Metabolism and Bioanalysis Letters
  44. In Vitro Tissue Construction for Organ-on-a-Chip Applications
    Yuya Morimoto, Nobuhito Mori, Shoji Takeuchi · 2019 · Bioanalysis
  45. Fabrication of cell culture microdevices for tissue engineering applications
    Joseph D. Cuiffi · 2012 · Elsevier eBooks
  46. Microfluidics for nanopharmaceutical and medical applications
    Friederike Adams, Christoph M. Zimmermann, Paola Luciani, Olivia M. Merkel · 2023 · Elsevier eBooks
  47. Microfluidic Cell Culture Systems for Drug Research
    Mingsha Jie, Jin‐Ming Lin · 2017 · Integrated analytical systems
  48. Generation of a multi-organ-chip-based liver equivalent for toxicity testing
    Eva-Maria Materne · 2014
  49. Development of thermoplastic elastomer microfluidic systems for bio-applications
    Emma Thomée · 2021
  50. What Is the Definitive Role of DMPK Research for Successful Drug Discovery and Development? Until Now and in the Future
    Hideki Hirabayashi · 2014 · Drug Metabolism and Pharmacokinetics
  51. Microfluidic in vitro model to study cell mechanisms and drug efficacy
    Venugopal Menon Nishanth · 2015
  52. An Investigation Into the Bioactive Components of Euphorbia hirta and Pandanus tectorius
    Ashley Blair Lipscomb · 2014
  53. Emerging Concepts and Techniques
    Joseph M. Steffen, Marlene C. Steffen · 2010 · Elsevier eBooks
  54. Organ-on-a-chip Systems
    Aleksandra Szuplewska, M. Chudy, Zbigniew Brzózka · 2017 · Springer eBooks
  55. Anti-Proliferative Effects of Garcinia Fruits in Breast Cancer Cells
    Harini Anandhi Senthilkumar · 2018
  56. Microfluidic Platforms for Biofabrication and 3D Tissue Modeling
    Minghao Nie, Shoji Takeuchi · 2019 · Royal Society of Chemistry eBooks
  57. 3D Modeling of Hepatic Tissue
    Mary C. Regier, Kelly R. Stevens · 2019 · Royal Society of Chemistry eBooks
  58. Emerging Concepts and Techniques
    Adrian Nañez, Helen J. McBride, T. Long, Joseph M. Steffen, Marlene C. Steffen · 2017 · Elsevier eBooks
  59. Microfluidic Organs-on-Chips to Reconstitute Cellular Microenvironments
    Yu‐suke Torisawa · 2019 · Bioanalysis
  60. Crypts-on-a-Chip: Developing an ex vivo Model of the Intestinal Crypts
    Brent J. Puthoff · 2019 · Carolina Digital Repository (University of North Carolina at Chapel Hill)
  61. 96-Well Format-Based Microfluidic Paltform for an in-Vitro Multiple Micro-Organ Network
    Chaewon Jin, Jinyoung Kim, Hongsoo Choi · 2020 · IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
  62. Human gut-on-chip as an intestinal model to predict compound absorption and toxicity
    Kornphimol Kulthong · 2020
  63. The artificial gut : integrating in vitro models of the human digestive tract with mass spectrometry
    Milou J.C. Santbergen · 2020
  64. Organ Chips in Safety Pharmacology
    Mihaela C. Stefan, Pooneh Soltantabar, Huifang Wang, Abhi Bhadran, Himanshu Polara, Tejas V. Shah · 2023 · Springer eBooks
  65. Bioengineering the intestinal niche on a chip: investigating signal transmission between the epithelium and enteric neurons
    Jessica R. Snyder · 2023
  66. Microfluidic Organs-on-Chips to Reconstitute Cellular Microenvironments
    Yu‐suke Torisawa · 2024 · Bioanalysis
  67. Organ Chips in Safety Pharmacology
    Mihaela C. Stefan, Pooneh Soltantabar, Huifang Wang, Abhi Bhadran, Himanshu Polara, Tejas V. Shah · 2024 · Springer eBooks
  68. Organ-on-a-chip in the diagnosis and treatment of chronic respiratory disorders and its application to advanced drug delivery systems
    Nitin Verma, Neha Kanojia, Komal Thapa, Prarit Chandel, Kamal Dua · 2024 · Elsevier eBooks
  69. Tumor-on-a-Chip: From Biomimetic Tumor-Immune Microenvironments to Therapeutic Insights
    Yüksel Çetin · 2025 · Biochemistry
  70. Liver-on-Chip: An Analysis of Liver Cell Types, Seeding Parameters, and Liver Function Assays
    Tenzin Choden Gyeltshen, Dimple Sajin, Hang Thu Ta · 2026 · Micromachines
  71. From dietary exposure to systemic toxicity: organ-on-chip and multi-organ microphysiological systems for green food toxicology
    Wenhan Liu, Yi Lu, Na Xu · 2026 · Frontiers in Nutrition
  72. Organ-on-a-chip: a microfluidic system of next frontier in medicine
    Lakshmi Prasanthi Nori, S Bhanumounika, Sarvan Manikiran Seethamraju · 2026 · SA pharmaceutical journal.
  73. Development and validation of an in vitro model to explore mechanisms of skeletal muscle toxicity
    William Dott · 2014 · Leicester Research Archive (University of Leicester)