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Cited by 421

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Gold Nanoparticle-Graphite-Like C3N4Nanosheet Nanohybrids Used for Electrochemiluminescent Immunosensor

Chen, Lichan, Zeng, Xiaoting, Si, Peng, Chen, Yingmei, Chi, Yuwu, Kim, Dong-Hwan, Chen, Guonan·2014·Analytical Chemistry

Abstract

Two-dimensional graphite-like carbon nitride nanosheets (g-C3N4 NSs) were hybridized with gold nanoparticles (Au NPs) to construct an electrochemiluminescence (ECL) immunosensor. The prepared Au NP-functionalized g-C3N4 NS nanohybrids (Au-g-C3N4 NHs) exhibit strong and stable cathodic ECL activity compared to g-C3N4 NSs due to the important roles of Au NPs in trapping and storing the electrons from the conduction band of g-C3N4 NSs, as well as preventing high energy electron-induced passivation of g-C3N4 NSs. On the basis of the improved ECL stability and ECL peak intensity of the Au-g-C3N4 NHs, a novel ECL immunosensor was developed to detect carcinoembryonic antigen (CEA) as a model target analyte. The ECL immunosensor has a sensitive response to CEA in a linear range of 0.02-80 ng mL(-1) with a detection limit of 6.8 pg mL(-1). Additionally, the proposed immunosensor shows high specificity, good reproducibility, and long-term stability.

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Crossref · 10.1021/ac403635f

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Metadata

Authors
Chen, L., Zeng, X., Si, P., Chen, Y., Chi, Y., Kim, D.-H., & Chen, G.
Venue
Analytical Chemistry
Published
2014-04-17
Volume
86
Issue
9
Pages
4188-4195
ISSN
  • 0003-2700 (ISSN-L)
  • 1520-6882
OpenAlex
W2329826869
Cited by
421
References
2
FWCI
15.82
Type
journal article
Language
en
Open access
closed

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