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Cited by 210

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Chip-Based Scanometric Detection of Mercuric Ion Using DNA-Functionalized Gold Nanoparticles

Lee, Jae-Seung, Mirkin, Chad A.·2008·Analytical Chemistry

Abstract

We have developed a chip-based scanometric method for the detection of mercuric ion (Hg (2+)). This method takes advantage of the cooperative binding and catalytic properties of DNA-functionalized gold nanoparticles and the selective binding of a thymine-thymine mismatch for Hg (2+). The limit of detection of this assay in buffer and environmentally relevant samples (lake water) is 10 nM (2 ppb) Hg (2+), which is the U.S. Environmental Protection Agency (EPA) limit of [Hg (2+)] for drinkable water and 1 order of magnitude lower than previous colorimetric assays. This assay is capable of discriminating Hg (2+) from 15 other environmentally relevant metal ions. The method is attractive for potential point-of-use applications due to its high throughput, convenient readout, and portability.

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Metadata

Authors
Lee, J.-S., & Mirkin, C. A.
Venue
Analytical Chemistry
Published
2008-07-30
Volume
80
Issue
17
Pages
6805-6808
ISSN
  • 0003-2700 (ISSN-L)
  • 1520-6882
OpenAlex
W2033043994
Cited by
210
References
1
FWCI
9.06
Type
journal article
Language
en
Open access
closed

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