The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Nanoholes As Nanochannels: Flow-through Plasmonic Sensing
Abstract
We combine nanofluidics and nanoplasmonics for surface-plasmon resonance (SPR) sensing using flow-through nanohole arrays. The role of surface plasmons on resonant transmission motivates the application of nanohole arrays as surface-based biosensors. Research to date, however, has focused on dead-ended holes, and therefore failed to harness the benefits of nanoconfined transport combined with SPR sensing. The flow-through format enables rapid transport of reactants to the active surface inside the nanoholes, with potential for significantly improved time of analysis and biomarker yield through nanohole sieving. We apply the flow-through method to monitor the formation of a monolayer and the immobilization of an ovarian cancer biomarker specific antibody on the sensing surface in real-time. The flow-through method resulted in a 6-fold improvement in response time as compared to the established flow-over method.
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Citations
Cites
The origins and the future of microfluidics
Whitesides, G. M. (2006) · Nature · doi:10.1038/nature05058 · Cited by 9,687
Cited by
SPR Biosensors: Historical Perspectives and Current Challenges
Singh, P. (2016) · Sensors and Actuators B: Chemical · doi:10.1016/j.snb.2016.01.118 · Cited by 608
LSPR Chip for Parallel, Rapid, and Sensitive Detection of Cancer Markers in Serum
Aćimović, S. S., Ortega, M. A., Sanz, V., Berthelot, J., Garcia-Cordero, J. L., Renger, J., Maerkl, S. J., Kreuzer, M. P., & Quidant, R. (2014) · Nano Letters · doi:10.1021/nl500574n · Cited by 310
Nanoplasmonic sensors for biointerfacial science
Jackman, J. A., Rahim Ferhan, A., & Cho, N.-J. (2017) · Chemical Society Reviews · doi:10.1039/c6cs00494f · Cited by 258
High-sensitivity nanophotonic sensors with passive trapping of analyte molecules in hot spots
Miao, X., Yan, L., Wu, Y., & Liu, P. Q. (2021) · Light: Science & Applications · doi:10.1038/s41377-020-00449-7 · Cited by 71
Metadata
- Authors
- Eftekhari, F., Escobedo, C., Ferreira, J., Duan, X., Girotto, E. M., Brolo, A. G., Gordon, R., & Sinton, D.
- Venue
- Analytical Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2009-05-01
- Volume
- 81
- Issue
- 11
- Pages
- 4308-4311
- ISSN
- 0003-2700 (ISSN-L)
- 1520-6882
- OpenAlex
- W2064765974
- Cited by
- 290
- References
- 1
- FWCI
- 14.36
- Type
- journal article
- Language
- en
- Open access
- closed
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