The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Cholesterol Sulfate Imaging in Human Prostate Cancer Tissue by Desorption Electrospray Ionization Mass Spectrometry
Open accessAbstract
Development of methods for rapid distinction between cancerous and non-neoplastic tissues is an important goal in disease diagnosis. To this end, desorption electrospray ionization mass spectrometry (DESI-MS) imaging was applied to analyze the lipid profiles of thin tissue sections of 68 samples of human prostate cancer and normal tissue. The disease state of the tissue sections was determined by independent histopathological examination. Cholesterol sulfate was identified as a differentiating compound, found almost exclusively in cancerous tissues including tissue containing precancerous lesions. The presence of cholesterol sulfate in prostate tissues might serve as a tool for prostate cancer diagnosis although confirmation through larger and more diverse cohorts and correlations with clinical outcome data is needed.
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Cites
Testosterone and Dihydrotestosterone Tissue Levels in Recurrent Prostate Cancer
Titus, M. A., Schell, M. J., Lih, F. B., Tomer, K. B., & Mohler, J. L. (2005) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-05-0525 · Cited by 488
Cited by
Lipids and cancer: Emerging roles in pathogenesis, diagnosis and therapeutic intervention
Butler, L. M., Perone, Y., Dehairs, J., Lupien, L. E., de Laat, V., Talebi, A., Loda, M., Kinlaw, W. B., & Swinnen, J. V. (2020) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2020.07.013 · Cited by 589
Ambient Sampling/Ionization Mass Spectrometry: Applications and Current Trends
Harris, G. A., Galhena, A. S., & Fernández, F. M. (2011) · Analytical Chemistry · doi:10.1021/ac200918u · Cited by 527
Mass spectrometry imaging under ambient conditions
Wu, C., Dill, A. L., Eberlin, L. S., Cooks, R. G., & Ifa, D. R. (2013) · Mass Spectrometry Reviews · doi:10.1002/mas.21360 · Cited by 488
Self-citationAmbient mass spectrometry: bringing MS into the “real world”
Alberici, R. M., Simas, R. C., Sanvido, G. B., Romão, W., Lalli, P. M., Benassi, M., Cunha, I. B. S., & Eberlin, M. N. (2010) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-010-3808-3 · Cited by 340
Overview of Mass Spectrometry-Based Metabolomics: Opportunities and Challenges
Gowda, G. A. N., & Djukovic, D. (2014) · Methods in Molecular Biology · doi:10.1007/978-1-4939-1258-2_1 · Cited by 334
Metadata
- Authors
- Eberlin, L. S., Dill, A. L., Costa, A. B., Ifa, D. R., Cheng, L., Masterson, T., Koch, M., Ratliff, T. L., & Cooks, R. G.
- Venue
- Analytical Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2010-04-07
- Volume
- 82
- Issue
- 9
- Pages
- 3430-3434
- ISSN
- 0003-2700 (ISSN-L)
- 1520-6882
- OpenAlex
- W2066377726
- Cited by
- 192
- References
- 1
- FWCI
- 7.88
- Type
- journal article
- Language
- en
- Open access
- green
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- Eberlin, L. S., Dill, A. L., Costa, A. B., Ifa, D. R., Cheng, L., Masterson, T., Koch, M., Ratliff, T. L., & Cooks, R. G. (2010). Cholesterol Sulfate Imaging in Human Prostate Cancer Tissue by Desorption Electrospray Ionization Mass Spectrometry. Analytical Chemistry. https://doi.org/10.1021/ac9029482
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