The DOI matches its Crossref record.
Multicolor Gold–Silver Nano-Mushrooms as Ready-to-Use SERS Probes for Ultrasensitive and Multiplex DNA/miRNA Detection
Abstract
Uniform silver-containing metal nanostructures with strong and stable surface-enhanced Raman scattering (SERS) signals hold great promise for developing ultrasensitive probes for biodetection. Nevertheless, the direct synthesis of such ready-to-use nanoprobes remains extremely challenging. Herein we report a DNA-mediated gold-silver nanomushroom with interior nanogaps directly synthesized and used for multiplex and simultaneous SERS detection of various DNA and RNA targets. The DNA involved in the nanostructures can act as not only gap DNA (mediated DNA) but also probe DNA (hybridized DNA), and DNA's involvement enables the nanostructures to have the inherent ability to recognize DNA and RNA targets. Importantly, we were the first to establish a new method for the generation of multicolor SERS probes using two different strategies. First Raman-labeled alkanethiol probe DNA was assembled on gold nanoparticles, and second, thiol-containing Raman reporters were coassembled with the probe DNA. The ready-to-use probes also give great potential to develop ultrasensitive detection methods for various biological molecules.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Ha, M., Kim, J.-H., You, M., Li, Q., Fan, C., & Nam, J.-M. (2019) · Chemical Reviews · doi:10.1021/acs.chemrev.9b00234 · Cited by 466
Self-citationMetasurface Micro/Nano-Optical Sensors: Principles and Applications
Qin, J., Jiang, S., Wang, Z., Cheng, X., Li, B., Shi, Y., Tsai, D. P., Liu, A. Q., Huang, W., & Zhu, W. (2022) · ACS Nano · doi:10.1021/acsnano.2c03310 · Cited by 359
Ngo, H. T., Freedman, E., Odion, R. A., Strobbia, P., De Silva Indrasekara, A. S., Vohra, P., Taylor, S. M., & Vo-Dinh, T. (2018) · Scientific Reports · doi:10.1038/s41598-018-21615-3 · Cited by 66
Nishitsuji, R., Kawasaki, D., Nakashima, T., Sueyoshi, K., Hisamoto, H., & Endo, T. (2026) · Soft Computing · doi:10.1007/s00500-026-11387-8
Metadata
- Authors
- Su, J., Wang, D., Nörbel, L., Shen, J., Zhao, Z., Dou, Y., Peng, T., Shi, J., Mathur, S., Fan, C., & Song, S.
- Venue
- Analytical Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2017-02-09
- Volume
- 89
- Issue
- 4
- Pages
- 2531-2538
- ISSN
- 0003-2700 (ISSN-L)
- 1520-6882
- OpenAlex
- W2580018860
- Cited by
- 222
- References
- 0
- FWCI
- 11.01
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Multicolor Gold–Silver Nano-Mushrooms as Ready-to-Use SERS Probes for Ultrasensitive and Multiplex DNA/miRNA Detection. https://app.cochat.ai/papers/10.1021/acs.analchem.6b04729
- The paper
- Su, J., Wang, D., Nörbel, L., Shen, J., Zhao, Z., Dou, Y., Peng, T., Shi, J., Mathur, S., Fan, C., & Song, S. (2017). Multicolor Gold–Silver Nano-Mushrooms as Ready-to-Use SERS Probes for Ultrasensitive and Multiplex DNA/miRNA Detection. Analytical Chemistry. https://doi.org/10.1021/acs.analchem.6b04729
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
