New Electrophiles and Strategies for Mechanism-Based and Targeted Covalent Inhibitor Design
Cited by (109)
Items 101–109 of 109
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- Lysine-targeted covalent inhibitors: mechanistic advances, pharmacological perspectives and translational challengesMingjin Luo, Luyu Ma, Guoshun Luo, Hua Xiang · 2026 · Biochemical Pharmacology
- BindingDB Entry 50021193: Emerging and Re-emerging Warheads for Targeted Covalent Inhibitors: An Update.BindingDB · 2025 · UC San Diego
- BindingDB Entry 50023340: Size-Dependent Target Engagement of Covalent Probes.BindingDB · 2026 · UC San Diego
- BindingDB Entry 50021521: Pitfalls and Considerations in Determining the Potency and Mutant Selectivity of Covalent Epidermal Growth Factor Receptor Inhibitors.BindingDB · 2025 · UC San Diego
- BindingDB Entry 50019889: Discovery of Novel Potent Covalent Glutathione Peroxidase 4 Inhibitors as Highly Selective Ferroptosis Inducers for the Treatment of Triple-Negative Breast Cancer.BindingDB · 2024 · UC San Diego
- BindingDB Entry 50013640: Novel irreversible covalent BTK inhibitors discovered using DNA-encoded chemistry.BindingDB · 2022 · UC San Diego
- BindingDB Entry 50015450: Novel Electrophilic Warhead Targeting a Triple-Negative Breast Cancer Driver in Live Cells Revealed by "Inverse Drug Discovery".BindingDB · 2023 · UC San Diego