The DOI matches its Crossref record; 76 of the 76 references it cites were found in a registry or an index.
Recent Advances in the Enantioselective Synthesis of Chiral Amines via Transition Metal-Catalyzed Asymmetric Hydrogenation
Open accessAbstract
Chiral amines are key structural motifs present in a wide variety of natural products, drugs, and other biologically active compounds. During the past decade, significant advances have been made with respect to the enantioselective synthesis of chiral amines, many of them based on catalytic asymmetric hydrogenation (AH). The present review covers the use of AH in the synthesis of chiral amines bearing a stereogenic center either in the α, β, or γ position with respect to the nitrogen atom, reported from 2010 to 2020. Therefore, we provide an overview of the recent advances in the AH of imines, enamides, enamines, allyl amines, and N-heteroaromatic compounds.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Fluorine in medicinal chemistry
Purser, S., Moore, P. R., Swallow, S., & Gouverneur, V. (2008) · Chem. Soc. Rev. · doi:10.1039/b610213c · Cited by 7,570
Fluorine in Pharmaceuticals: Looking Beyond Intuition
Müller, K., Faeh, C., & Diederich, F. (2007) · Science · doi:10.1126/science.1131943 · Cited by 6,596
The Medicinal Chemist’s Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates
Roughley, S. D., & Jordan, A. M. (2011) · Journal of Medicinal Chemistry · doi:10.1021/jm200187y · Cited by 2,725
New Chiral Phosphorus Ligands for Enantioselective Hydrogenation
Tang, W., & Zhang, X. (2003) · Chemical Reviews · doi:10.1021/cr020049i · Cited by 2,570
Fluorine in Medicinal Chemistry and Chemical Biology
(2009) · Wiley eBooks · doi:10.1002/9781444312096 · Cited by 1,731
Organic synthesis provides opportunities to transform drug discovery
Blakemore, D. C., Castro, L., Churcher, I., Rees, D. C., Thomas, A. W., Wilson, D. M., & Wood, A. (2018) · Nature Chemistry · doi:10.1038/s41557-018-0021-z · Cited by 1,485
Asymmetric Hydrogenation of Heteroarenes and Arenes
Wang, D.-S., Chen, Q.-A., Lu, S.-M., & Zhou, Y.-G. (2012) · Chemical Reviews · doi:10.1021/cr200328h · Cited by 1,170
Chemistry and Biology of the Tetrahydroisoquinoline Antitumor Antibiotics
Scott, J. D., & Williams, R. M. (2002) · Chemical Reviews · doi:10.1021/cr010212u · Cited by 1,149
Advances in the Chemistry of Tetrahydroquinolines
Sridharan, V., Suryavanshi, P. A., & Menéndez, J. C. (2011) · Chemical Reviews · doi:10.1021/cr100307m · Cited by 1,089
Kobayashi, S., Mori, Y., Fossey, J. S., & Salter, M. M. (2011) · Chemical Reviews · doi:10.1021/cr100204f · Cited by 988
Metadata
- Authors
- Cabré, A., Verdaguer, X., & Riera, A.
- Venue
- Chemical Reviews
- Publisher
- American Chemical Society (ACS)
- Published
- 2021-10-22
- Volume
- 122
- Issue
- 1
- Pages
- 269-339
- ISSN
- 0009-2665 (ISSN-L)
- 1520-6890
- OpenAlex
- W3206637869
- Cited by
- 477
- References
- 76
- FWCI
- 2.38
- Type
- journal article
- Language
- en
- Open access
- hybrid
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Recent Advances in the Enantioselective Synthesis of Chiral Amines via Transition Metal-Catalyzed Asymmetric Hydrogenation. https://app.cochat.ai/papers/10.1021/acs.chemrev.1c00496
- The paper
- Cabré, A., Verdaguer, X., & Riera, A. (2022). Recent Advances in the Enantioselective Synthesis of Chiral Amines via Transition Metal-Catalyzed Asymmetric Hydrogenation. Chemical Reviews. https://doi.org/10.1021/acs.chemrev.1c00496
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
