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Cited by 508

The DOI matches its Crossref record; 465 of the 465 references it cites were found in a registry or an index.

Microbiome and Human Health: Current Understanding, Engineering, and Enabling Technologies

Open access
Aggarwal, Nikhil, Kitano, Shohei, Puah, Ginette Ru Ying, Kittelmann, Sandra, Hwang, In Young, Chang, Matthew Wook·2023·Chemical Reviews

Abstract

The human microbiome is composed of a collection of dynamic microbial communities that inhabit various anatomical locations in the body. Accordingly, the coevolution of the microbiome with the host has resulted in these communities playing a profound role in promoting human health. Consequently, perturbations in the human microbiome can cause or exacerbate several diseases. In this Review, we present our current understanding of the relationship between human health and disease development, focusing on the microbiomes found across the digestive, respiratory, urinary, and reproductive systems as well as the skin. We further discuss various strategies by which the composition and function of the human microbiome can be modulated to exert a therapeutic effect on the host. Finally, we examine technologies such as multiomics approaches and cellular reprogramming of microbes that can enable significant advancements in microbiome research and engineering.

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Crossref · 10.1021/acs.chemrev.2c00431

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Metadata

Authors
Aggarwal, N., Kitano, S., Puah, G. R. Y., Kittelmann, S., Hwang, I. Y., & Chang, M. W.
Venue
Chemical Reviews
Published
2022-11-01
Volume
123
Issue
1
Pages
31-72
ISSN
  • 0009-2665 (ISSN-L)
  • 1520-6890
OpenAlex
W4307847181
Cited by
508
References
465
FWCI
7.26
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Microbiome and Human Health: Current Understanding, Engineering, and Enabling Technologies. https://app.cochat.ai/papers/10.1021/acs.chemrev.2c00431
The paper
Aggarwal, N., Kitano, S., Puah, G. R. Y., Kittelmann, S., Hwang, I. Y., & Chang, M. W. (2023). Microbiome and Human Health: Current Understanding, Engineering, and Enabling Technologies. Chemical Reviews. https://doi.org/10.1021/acs.chemrev.2c00431

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.