Supramolecular Helical Systems: Helical Assemblies of Small Molecules, Foldamers, and Polymers with Chiral Amplification and Their Functions
Open accessAbstract
In this review, we describe the recent advances in supramolecular helical assemblies formed from chiral and achiral small molecules, oligomers (foldamers), and helical and nonhelical polymers from the viewpoints of their formations with unique chiral phenomena, such as amplification of chirality during the dynamic helically assembled processes, properties, and specific functionalities, some of which have not been observed in or achieved by biological systems. In addition, a brief historical overview of the helical assemblies of small molecules and remarkable progress in the synthesis of single-stranded and multistranded helical foldamers and polymers, their properties, structures, and functions, mainly since 2009, will also be described.
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The helical conformation adopted by the main chain of certain types of polymers can be 'amplified', i.e. single handed fragments may form even if composed of non-enantiopure building blocks.
“the helical conformation adopted by the main chain of certain types of polymers can be ''amplified'', i.e. that single handed fragments may form even if composed of non-enantiopure building blocks.”
From Possible chemical and physical scenarios towards biological homochirality (2022) · cites this paper as [563]
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Possible chemical and physical scenarios towards biological homochirality
Sallembien, Q., Bouteiller, L., Crassous, J., & Raynal, M. (2022) · Chemical Society Reviews · doi:10.1039/d1cs01179k · Cited by 186 · see citing works
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- Authors
- Yashima, E., Ousaka, N., Taura, D., Shimomura, K., Ikai, T., & Maeda, K.
- Affiliations
- Nagoya University (JP)
- Kanazawa University (JP)
- Venue
- Chemical Reviews
- Publisher
- American Chemical Society (ACS)
- Published
- 2016-10-18
- Volume
- 116
- Issue
- 22
- Pages
- 13752-13990
- ISSN
- 0009-2665 (ISSN-L)
- 1520-6890
- OpenAlex
- W2534278659
- Cited by
- 2,004
- References
- 5
- Citations by year
- 2026: 160 · 2025: 192 · 2024: 231 · 2023: 226 · 2022: 222 · 2021: 228 · 2020: 220 · 2019: 197 · 2018: 189 · 2017: 134 · 2016: 5
- FWCI
- 8.35
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Chemical Reviews (publishedVersion, other-oa)
- PubMed (publishedVersion)
- Funders
- Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research (S), no. 25220804)
- Topics
- Physical Sciences › Chemistry › Organic Chemistry › Supramolecular Chemistry and Complexes
- Physical Sciences › Materials Science › Biomaterials › Supramolecular Self-Assembly in Materials
- Physical Sciences › Chemistry › Organic Chemistry › Synthesis and Properties of Aromatic Compounds
- Keywords
- chiral amplification, foldamers, helical polymers, oligomers, helical assembly, chirality
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