Microfluidic Mixing: A General Method for Encapsulating Macromolecules in Lipid Nanoparticle Systems
Leung, Alex K. K., Tam, Yuen Yi C., Chen, Sam, Hafez, Ismail M., Cullis, Pieter R.·2015·The Journal of Physical Chemistry B
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- Time evolution of PEG-shedding and serum protein coronation determines the cell uptake kinetics and delivery of lipid nanoparticle formulated mRNAAudrey Gallud, M. J. Munson, Kai Liu, Alexander Idström, Hanna M. G. Barriga, Seyed R. Tabaei, Nima Aliakbarinodehi, Miina Ojansivu, Quentin Lubart, James Doutch et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- mRNA Synthesis and Encapsulation in Ionizable Lipid NanoparticlesRebecca E. McKenzie, Jordan James Minnell, Mitch Ganley, Gavin F. Painter, Sarah L. Draper · 2023 · Current Protocols
- Understanding the Manufacturing Process of Lipid Nanoparticles for mRNA Delivery Using Machine LearningShinya Sato, Syusuke Sano, Hiroki Muto, Kenji Kubara, Keita Kondo, Takayuki Miyazaki, Yuta Suzuki, Yoshifumi Uemoto, Koji Ukai · 2024 · Chemical and Pharmaceutical Bulletin
- Advances in RNAi therapeutic delivery to leukocytes using lipid nanoparticlesSrinivas Ramishetti, Dalit Landesman‐Milo, Dan Peer · 2016 · Journal of drug targeting
- Shaping the future from the small scale: dry powder inhalation of CRISPR-Cas9 lipid nanoparticles for the treatment of lung diseasesSimone Pinto Carneiro, Antonietta Greco, Enrica Chiesa, Ida Genta, Olivia M. Merkel · 2023 · Expert Opinion on Drug Delivery
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- Microfluidic technologies for enhancing the potency, predictability and affordability of adoptive cell therapiesZongjie Wang, Shana O. Kelley · 2025 · Nature Biomedical Engineering
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