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Nanoengineered Colloidal Inks for 3D Bioprinting
Open accessAbstract
Nanoengineered hydrogels offer the potential to design shear-thinning bioinks for three-dimensional (3D) bioprinting. Here, we have synthesized colloidal bioinks composed of disk-shaped two-dimensional (2D) nanosilicates (Laponite) and poly(ethylene glycol) (PEG). The addition of Laponite reinforces the PEG network and increases viscosity, storage modulus, and network stability. PEG-Laponite hydrogels display shear-thinning and self-recovery characteristics due to rapid internal phase rearrangement. As a result, a range of complex patterns can be printed using PEG-Laponite bioinks. The 3D bioprinted structure has similar mechanical properties compared to the as-casted structure. In addition, encapsulated cells within the PEG-Laponite bioink show high viability after bioprinting. Overall, this study introduces a new class of PEG-Laponite colloidal inks for bioprinting and cell delivery.
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Cited by
Printability and shape fidelity of bioinks in 3D bioprinting
Schwab, A., Levato, R., D’Este, M., Piluso, S., Eglin, D., & Malda, J. (2020) · Chemical Reviews · doi:10.1021/acs.chemrev.0c00084 · Cited by 1,359
Self-Healing Injectable Hydrogels for Tissue Regeneration
Bertsch, P., Diba, M., Mooney, D. J., & Leeuwenburgh, S. C. G. (2023) · Chemical Reviews · doi:10.1021/acs.chemrev.2c00179 · Cited by 892
Hydrogel Bioink Reinforcement for Additive Manufacturing: A Focused Review of Emerging Strategies
Chimene, D., Kaunas, R., & Gaharwar, A. K. (2020) · Advanced Materials · doi:10.1002/adma.201902026 · Cited by 600
Self-citationShear-Thinning and Thermo-Reversible Nanoengineered Inks for 3D Bioprinting
Wilson, S. A., Cross, L. M., Peak, C. W., & Gaharwar, A. K. (2017) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.7b13602 · Cited by 369
Self-citationNadernezhad, A., Caliskan, O. S., Topuz, F., Afghah, F., Erman, B., & Koc, B. (2019) · ACS Applied Bio Materials · doi:10.1021/acsabm.8b00665 · Cited by 91
Metadata
- Authors
- Peak, C. W., Stein, J., Gold, K. A., & Gaharwar, A. K.
- Venue
- Langmuir
- Publisher
- American Chemical Society (ACS)
- Published
- 2017-10-25
- Volume
- 34
- Issue
- 3
- Pages
- 917-925
- ISSN
- 0743-7463 (ISSN-L)
- 1520-5827
- OpenAlex
- W2762925038
- Cited by
- 178
- References
- 0
- FWCI
- 6.63
- Type
- journal article
- Language
- en
- Open access
- green
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- Peak, C. W., Stein, J., Gold, K. A., & Gaharwar, A. K. (2018). Nanoengineered Colloidal Inks for 3D Bioprinting. Langmuir. https://doi.org/10.1021/acs.langmuir.7b02540
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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