The DOI matches its Crossref record; 44 of the 44 references it cites were found in a registry or an index.
Two-Dimensional Ultrathin MXene Ceramic Nanosheets for Photothermal Conversion
Abstract
Ceramic biomaterials have been investigated for several decades, but their potential biomedical applications in cancer therapy have been paid much less attentions, mainly due to their lack of related material functionality for combating the cancer. In this work, we report, for the first time, that MAX ceramic biomaterials exhibit the unique functionality for the photothermal ablation of cancer upon being exfoliated into ultrathin nanosheets within atomic thickness (MXene). As a paradigm, biocompatible Ti 3 C 2 nanosheets (MXenes) were successfully synthesized based on a two-step exfoliation strategy of MAX phase Ti 3 AlC 2 by the combined HF etching and TPAOH intercalation. Especially, the high photothermal-conversion efficiency and in vitro / in vivo photothermal ablation of tumor of Ti 3 C 2 nanosheets (MXenes) were revealed and demonstrated, not only in the intravenous administration of soybean phospholipid modified Ti 3 C 2 nanosheets but also in the localized intratumoral implantation of a phase-changeable PLGA/Ti 3 C 2 organic–inorganic hybrid. This work promises the great potential of Ti 3 C 2 nanosheets (MXenes) as a novel ceramic photothermal agent used for cancer therapy and may arouse much interest in exploring MXene-based ceramic biomaterials to benefit the biomedical applications.
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Cites
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Two‐Dimensional Nanocrystals Produced by Exfoliation of Ti3AlC2
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Self-citationTwo-Dimensional Transition Metal Carbides
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Cation Intercalation and High Volumetric Capacitance of Two-Dimensional Titanium Carbide
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Flexible and conductive MXene films and nanocomposites with high capacitance
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Cited by
2D/2D Heterojunction of Ultrathin MXene/Bi2WO6 Nanosheets for Improved Photocatalytic CO2 Reduction
Cao, S., Shen, B., Tong, T., Fu, J., & Yu, J. (2018) · Advanced Functional Materials · doi:10.1002/adfm.201800136 · Cited by 1,543
Fluorine‐Free Synthesis of High‐Purity Ti3C2Tx (T=OH, O) via Alkali Treatment
Li, T., Yao, L., Liu, Q., Gu, J., Luo, R., Li, J., Yan, X., Wang, W., Liu, P., Chen, B., et al. (2018) · Angewandte Chemie International Edition · doi:10.1002/anie.201800887 · Cited by 1,457
Recent advance in MXenes: A promising 2D material for catalysis, sensor and chemical adsorption
Zhu, J., Ha, E., Zhao, G., Zhou, Y., Huang, D., Yue, G., Hu, L., Sun, N., Wang, Y., Lee, L. Y. S., et al. (2017) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2017.09.012 · Cited by 659
Xiu, L., Wang, Z., Yu, M., Wu, X., & Qiu, J. (2018) · ACS Nano · doi:10.1021/acsnano.8b02849 · Cited by 588
Selective Etching of Silicon from Ti3SiC2 (MAX) To Obtain 2D Titanium Carbide (MXene)
Alhabeb, M., Maleski, K., Mathis, T. S., Sarycheva, A., Hatter, C. B., Uzun, S., Levitt, A., & Gogotsi, Y. (2018) · Angewandte Chemie International Edition · doi:10.1002/anie.201802232 · Cited by 452
Metadata
- Authors
- Lin, H., Wang, X., Yu, L., Chen, Y., & Shi, J.
- Venue
- Nano Letters
- Publisher
- American Chemical Society (ACS)
- Published
- 2016-12-30
- Volume
- 17
- Issue
- 1
- Pages
- 384-391
- ISSN
- 1530-6984 (ISSN-L)
- 1530-6992
- OpenAlex
- W2563556731
- Cited by
- 1,314
- References
- 44
- FWCI
- 34.65
- Type
- journal article
- Language
- en
- Open access
- closed
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