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Cited by 218

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Aluminum Nanocrystals: A Sustainable Substrate for Quantitative SERS-Based DNA Detection

Tian, Shu, Neumann, Oara, McClain, Michael J., Yang, Xiao, Zhou, Linan, Zhang, Chao, Nordlander, Peter, Halas, Naomi J.·2017·Nano Letters

Abstract

Since its discovery in the 1970s, surface-enhanced Raman scattering (SERS) has been primarily associated with substrates composed of nanostructured noble metals. Here we investigate chemically synthesized nanocrystal aggregates of aluminum, an inexpensive, highly abundant, and sustainable metal, as SERS substrates. Al nanocrystal aggregates are capable of substantial near-infrared SERS enhancements, similar to Au nanoparticles. The intrinsic nanoscale surface oxide of Al nanocrystals supports molecule-substrate interactions that differ dramatically from noble metal substrates. The preferential affinity of the single-stranded DNA (ssDNA) phosphate backbone for the Al oxide surface preserves both the spectral features and nucleic acid cross sections relative to conventional Raman spectroscopy, enabling quantitative ssDNA detection and analysis.

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Metadata

Authors
Tian, S., Neumann, O., McClain, M. J., Yang, X., Zhou, L., Zhang, C., Nordlander, P., & Halas, N. J.
Venue
Nano Letters
Published
2017-07-06
Volume
17
Issue
8
Pages
5071-5077
ISSN
  • 1530-6984 (ISSN-L)
  • 1530-6992
OpenAlex
W2731853619
Cited by
218
References
2
FWCI
9.55
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Aluminum Nanocrystals: A Sustainable Substrate for Quantitative SERS-Based DNA Detection. https://app.cochat.ai/papers/10.1021/acs.nanolett.7b02338
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Tian, S., Neumann, O., McClain, M. J., Yang, X., Zhou, L., Zhang, C., Nordlander, P., & Halas, N. J. (2017). Aluminum Nanocrystals: A Sustainable Substrate for Quantitative SERS-Based DNA Detection. Nano Letters. https://doi.org/10.1021/acs.nanolett.7b02338

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